Abstract: Synthetically produced substantially pure biologically active compounds having the general formula ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.20 alkyl, alkenyl, aryl, aralkyl, cycloalkyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkenyl, alkylcycloalkenyl, or cycloalkenylalkyl;R.sub.2 is hydrogen, C.sub.1 -C.sub.10 alkyl or an amide-substituted alkyl having up to 10 carbon atoms;R.sub.3 is a cyclic, straight or branched chain hydrocarbon group having 2-12 carbon atoms, particularly --(CH.sub.2).sub.n --, wherein n is 2-12; orR.sub.2 and R.sub.3 are linked together to form an alkylene chain; andR.sub.4 is selected from ##STR2## (substituted or unsubstituted carbamimidoyl), ##STR3## (dimethylpyrimidyl), or ##STR4## (carbamyl) wherein each of R.sub.5, R.sub.6, and R.sub.7 is hydrogen or the same or different C.sub.1 -C.sub.8 alkyl group. The compounds are useful as bactericides for a wide variety of bacteria, including S.pyogenes, B.subtilis, K.pneumoniae, M.avium, B.fragilis, C.perfringens and C.albicans.

Abstract: Soluble antigen, specific for Babesia parasites, is isolated from growth media of Babesia-infected erythrocytes in cell culture and characterized, inter alia, by its ability to inhibit the capacity of specific Babesia serum antibodies to neutralize infectivity of Babesia merozoites in vitro. Antigen preparations provide immunologically active components useful for vaccination of animals against infection by Babesia parasites and may be employed in the preparation of diagnostic reagents.

Abstract: Hydrophilic biopolymeric copolyelectrolytes comprising (a) a water-soluble linear anionic protein polyelectrolyte component derived from keratin and (b) a water-soluble linear cationic biopolymer polyelectrolyte component derived from at least one biopolymer selected from the group consisting of collagen and a glucosaminoglycan. Hydrogel membranes formed from the copolyelectrolytes are useful as biodegradable dressings for denuded tissue wound sites.

Abstract: A hypnotic composition and method of inducing sleep in a mammal by administering to a mammal in a pharmaceutical carrier a hypnotically effective dose of a salt of 2-amino-3-(1-naphthyl) propanoic acid in the form of an injectable solution, capsule tablet or syrup.

Abstract: Plasmid-assisted molecular breeding procedures for generating pure and mixed cultures of microorganisms capable of dissimilating environmentally persistent chemical compounds. Continuously cultured growth of microorganisms is carried out in the presence of a source of DNA plasmids participative in dissimilation of compounds structurally analogous to the persistent compounds and under chemostatic conditions including gradually increasing concentrations of the persistent compound. Novel microorganism products of the procedures include a mixed Arthrobacter and Pseudomonas culture, A.T.C.C. 39028, capable of total degradation of mixed polychlorinated biphenyls (e.g., Arochlor 1221) and a pure culture of Pseudomonas cepacia, A.T.C.C. 39027, which can utilize 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) as its sole carbon source. Disclosed also are procedures for using pure and mixed cultures of the invention in degrading persistent compounds contaminating soil and aqueous environments.

Abstract: Interferon glycoprotein isolates of heterologous species origin are subjected to treatment in a digestive environment and non-species-specific biologically active fractions thereof are administered, preferably through digestive tract tissue, to the circulatory system of mammals, including humans, to secure antiviral, antiproliferative (e.g., antineoplastic) and immunomodulatory (e.g., immunopotentiating) effects ordinarily associated only with parenteral administration of homologous species interferon.

Abstract: A means and method for comparing an incoming sequential string of digitally encoded characters from a database stored in a conventional memory against a pattern with an arbitrary number of elements, comprising specified characters or character types (alphabetic, numeric, delimiter, etc.) or tokens to indicate the matching of a specified or arbitrary number of input characters, is disclosed. The system comprises a number of digital machines, sequenced by control words fetched from their memories. The control words may indicate the current input character or character type of interest for each machine, the address of the potential next control word of the machine, a flag indicating the successful completion of a match, and other control fields.

Abstract: A planar antenna is described which employs a pair of closely spaced parallel ground planes and a radiating element which is a composite aperture (hybrid slot) formed into the upper ground plane. One portion of the radiating element is a long narrow slot which may have the shape of a rectangle of high aspect ratio. The other portion is an annular slot which may be circular in shape. Electromagnetic energy is conveyed to and from the slots in the upper ground plane by means of a feed conductor parallel to and sandwiched between the two ground planes. The maximum of the resulting field pattern is in the plane of the antenna and the pattern may be either directional or omnidirectional in that plane. When used as a receiving antenna, this antenna responds to both the electric and magnetic fields.

Abstract: The present invention prepares protein hydrolyzates by reacting selected protein material with at least one proteolytic enzyme and recovering the low molecular weight protein material by ultrafiltration while recycling the high molecular weight material and proteolytic enzyme for further hydrolysis. A series of ultrafilters of varying permeability may also be used.

Abstract: The disclosure is directed to a semiconductor device comprising an active region between a pair of injecting/collecting layers, the active region comprising at least one layer of a first binary semiconductor material disposed between coupling barriers of a second different binary semiconductor material that is lattice matched to the first binary semiconductor material. In a preferred embodiment the active region comprises one or more layers of gallium arsenide separated by aluminum arsenide barrier layers.

Abstract: An ocular insert is disclosed that is attachable to the third eyelid of animals to provide controlled delivery of ophthalmic medication. The insert includes a disc impregnated with medication in controlled-release form and a biodegradable spear for attachment of the insert to the third eyelid. An insert effective for treatment of infectious bovine keratoconjunctivitis comprises a disc impregnated with chloramphenicol sodium monosuccinate and a spear of biodegradable polylactic acid which provides for retention of the insert in the eye, and consequent medication, for up to seven days.

Abstract: Contraceptive method comprises maintaining in the genital tract of a mammal an ester of 4-guanidinobenzoic acid and certain substituted phenols in a concentration effective to inhibit the fertilization of ova. In addition to effectively inhibiting the enzymes necessary for conception, the compounds used in the method of the invention are advantageous in possessing low toxicity. Further, the phenolic materials which may be liberated on hydrolysis of the 4-guanidinobenzoates in the genital tract of the animal are low in toxic, caustic or irritating properties, so that the contraceptive compositions are suitable for long-term use without adverse side-effects.

Abstract: Novel heterogeneous catalysts consist essentially of an anion exchange resin to which is bound ionically an anionic metal carbonyl species having the general formula M.sub.n (CO).sub.m (X).sub.p.sup.z- where M is a transition metal such as for example rhodium, cobalt, ruthenium, osmium, iridium, or iron; X is an anion, for example halide, hydride, or alkyl; n ranges from 1 to 12; m ranges from 1 to 34; p ranges from 0 to 2n+1; and z is an integer charge ranging from 1 to 5. The catalyst in which M is rhodium, m=2, p=2, n=1,and z=1 is highly effective for the carbonylation of alcohols to acids and esters. Many of these anionic species have utility in the hydroformylation of olefins.

Abstract: Contraceptive method comprises maintaining in the genital tract of a female mammal a pyrazolone derivative in a concentration effective to inhibit the fertilization of ova. In addition to effectively inhibiting the enzymes or other sperm components necessary for conception, the compounds used in the method of the invention are advantageous in having low toxic, caustic or irritating properties, so that the contraceptive compositions are suitable for long-term use without adverse side-effects.

Abstract: Apparatus for separating an undesired foreign fluid, such as water, from the working fluid, such as ammonia, in a low temperature difference power plant which includes an evaporator and a condensor. A flash separator unit vaporizes the working fluid and separates it from the undesired foreign fluid. The vaporized working fluid is condensed in the condensor. The undesired foreign fluid is accumulated in the evaporator from which it can then be removed. In an alternative embodiment, the separated foreign fluid and liquid ammonia collected in the flash separator unit are not returned to the evaporator, but instead, are coupled back into the flash separator where the separated foreign fluid accumulates so that at the end of the separation process, the undesired foreign fluid can be removed from the flash separator. An alternative embodiment enables the power generating system to continue in operation, although with a decreased capacity during the fluid separation process.

Abstract: Continuous process for converting coal to gaseous fuel with production of Portland cement as a by-product comprises the step of pelletizing a mixture of finely divided coal and limestone, heating (coking) the pellets in a reducing gas atmosphere to liberate volatile fuel products, and converting a substantial proportion of the residual carbon in the pellets to CO and hydrogen by the water-gas reaction, the inorganic constituents of the coal being simultaneously converted to Portland cement clinkers.

Abstract: A multilayer, III-V semiconductive structure can be disordered and shifted up in energy gap into a single crystalline form by a Zinc diffusion. More specifically, all or selected portions of a multilayer of either gallium arsenide/aluminum arsenide or gallium arsenide/aluminum gallium arsenide can be converted into single crystal aluminum gallium arsenide having a higher energy gap than that of the original structure by the process of a Zinc diffusion at low temperature. Other active devices can then be constructed in the higher energy gap material using established semiconductor processing steps.

Abstract: A textured soybean product is produced from full-fat soybean by hydrating whole soybean by treatment with a dilute alkaline solution; mixing the hydrated soybean with full-fat soy flour and equilibrating the moisture content thereof; and passing the mixture through an extrusion cooker. The textured product has excellent flavor, color, and appearance, and can be formulated into an all-vegetable ground meat analogue or it can be used as an extender in blends with ground meat.

Abstract: Advantageous operation can be achieved in a semiconductor heterostructure light emitting device by utilizing a single thin active layer which exhibits quantum size effects. It has been found that performance can be degraded by employing a single quantum layer that is thinner than a certain minimum thickness, this minimum thickness being about 100 Angstroms, (the approximate carrier scattering path length). In one form of the invention, there is provided a semiconductor heterostructure device which includes first and second relatively wide bandgap semiconductor regions of opposite conductivity types. A single quantum well active layer is disposed between the first and second regions. The active layer is formed of a relatively narrow bandgap semiconductor having a thickness which is in the range of about 100 to 400 Angstroms, and is preferably about 200 Angstroms.

Abstract: A semiconducting internal boundary layer ceramic composition having a fine grain structure suitable for use in thin-layer multilayer capacitors is made in one step by firing a mixture comprising a major amount of finely divided strontium titanate, a minor amount of a compound containing either strontium or titanium, or an element functionally equivalent thereto, a minor amount of a semiconductor forming ingredient (dopant), the identity of which depends on whether the mixture is rich in strontium or in titanium, and a minor amount of a counterdopant selected from cuprous oxide or silver oxide. When the mixture is rich in titanium, the chemical doping agent used to produce semiconductivity is an oxide of a trivalent metal selected from bismuth, boron, iron, antimony, lanthanum and the rare earth and transition metals. When the mixture is rich in strontium, the dopant is an oxide of a pentavalent or hexavalent metal selected from tungsten (+6), niobium (+5), tantalum (+5), and molybdenum (+6).