Patents Assigned to The University of Queensland
  • Patent number: 11204404
    Abstract: A pre-polarisation magnet arrangement for generating a pre-polarisation field for use in a low field magnetic resonance imaging process, the pre-polarisation magnet arrangement including a pre-polarisation field array including a plurality of permanent pre-polarisation magnets mounted in a support and provided in a circumferentially spaced arrangement surrounding a field of view, a number of the pre-polarisation magnets being movable between respective first and second positions, wherein in the first position the pre-polarisation magnets are configured as a cylindrical Halbach array to generate a pre-polarisation field in the field of view and in the second position the pre-polarisation magnets are configured to minimize the pre-polarisation field in the field of view.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: December 21, 2021
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Michael Werner Vogel, David Charles Reutens, Andrea Giorni, Ruben Pellicer-Guridi, Viktor Vegh
  • Patent number: 11198632
    Abstract: A method for treating a sludge derived from sewage or wastewater, the method comprising subjecting the sludge to a treatment step at a pH of 8.9 or greater and a free ammonia (FA) content of 100 mg NH3—N/L or greater. The treated sludge may be fed to a bioreactor to produce methane.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: December 14, 2021
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Qilin Wang, Zhiguo Yuan, Haoran Duan, Wei Wei
  • Publication number: 20210347869
    Abstract: The invention relates to tau, to antibodies and related fragments thereof for binding to tau, to production of said antibodies and fragments and to use of said antibodies and fragments for detection and therapy of various conditions, including tauopathies. The invention also relates to compositions comprising tau antibodies for binding to tau and their use in combination with acoustic energy.
    Type: Application
    Filed: October 17, 2018
    Publication date: November 11, 2021
    Applicant: THE UNIVERSITY OF QUEENSLAND
    Inventors: Juergen GOETZ, Rebecca NISBET, Phillip JANOWICZ, Gerhard LEINENGA
  • Patent number: 11136351
    Abstract: The invention relates to alpha conotoxin (?-conotoxin) peptides and methods for their preparation. Also described are pharmaceutical compositions comprising alpha conotoxin (?-conotoxin) peptides and their use in the treatment or prevention of indications 5 associated with nicotinic acetylcholine receptors and/or voltage gated calcium channels.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: October 5, 2021
    Assignee: The University of Queensland
    Inventors: Richard James Clark, James Travis Daniel
  • Patent number: 11130731
    Abstract: The present invention provides for certain sulfonyl ureas and related compounds which have advantageous properties and show useful activity in the inhibition of activation of the NLRP3 inflammasome. Such compounds are useful in the treatment of a wide range of disorders in which the inflammation process, or more specifically the NLRP3 inflammasome, have been implicated as being a key factor.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: September 28, 2021
    Assignees: The Provost, Fellows, Foundation Scholars, And The Other Members Of Board, Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin, The University Of Queensland
    Inventors: Luke O'Neill, Rebecca Coll, Matthew Cooper, Avril Robertson, Kate Schroder
  • Publication number: 20210292397
    Abstract: The present disclosure relates to compositions and methods for inhibiting bacterial aggregation, and in particular, to compositions and methods that inhibit autotransporter-mediated bacterial aggregation or attachment. Described herein are autotransporter binding molecules such as antibodies and antigen binding fragments thereof. The autotransporter binding molecules block self-association between autotransporters and autotransporter-mediated surface attachment.
    Type: Application
    Filed: February 22, 2021
    Publication date: September 23, 2021
    Applicants: La Trobe University, The University of Queensland
    Inventors: Begona Heras, Jason Paxman, Mark Schembri, Alvin Lo
  • Patent number: 11124550
    Abstract: This invention relates to peptides and their use for modulating sodium channels. More particularly, the present invention relates to peptides and their use in methods of enhancing Nav1.1 activity and for treating or preventing conditions associated with Nav1.1 activity.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: September 21, 2021
    Assignees: THE UNIVERSITY OF QUEENSLAND, THE JOHNS HOPKINS UNIVERSITY, THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Steven Petrou, Glenn King, Frank Bosmans, David Julius, Jeremiah Osteen, Chuchu Zhang
  • Patent number: 11105802
    Abstract: The present disclosure relates to biofragment compositions that comprise bioparticle fragments and at least one heterologous antigen-binding molecule. In some embodiments, the biofragment is typically derived from a larger, intact bioparticle that express the at least one heterologous antigen-binding molecule at the surface, and the biofragment has increased solubility to facilitate assays for antigen detection. The disclosure also relates the related methods of using and making the biofragment compositions, as well as systems and devices implementing the biofragment compositions. In some embodiments, the related methods, systems and devices do not require additional detection reagents, such as animal derived detection antibodies.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: August 31, 2021
    Assignees: SEATTLE CHILDREN'S HOSPITAL, The University of Queensland
    Inventors: Yadveer Grewal, Gerard A. Cangelosi, Muhammad J. A. Shiddiky, Matt Trau
  • Patent number: 11095490
    Abstract: A transmitter of a DFT-based communications system including an orthogonal precoder for transforming modulated data symbols using a unitary transform, wherein the data 5 symbols are mapped to subcarriers of the transmitter and the computational complexity of the transform is linear with respect to the number of the subcarriers.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: August 17, 2021
    Assignee: The University of Queensland
    Inventor: Ian Vaughan Lyndon Clarkson
  • Patent number: 11045502
    Abstract: Disclosed are methods for isolating endothelial progenitor cells (EPC). More particularly, the present invention discloses methods for isolating endothelial progenitor cells that exhibit self-renewal and differentiation capacity. The isolated cellular population of the present invention is useful in a wide range of clinical and research setting including inter alia, the in vitro or in vivo generation of endothelial cells and the therapeutic or prophylactic treatment of a range of conditions via the administration of these cells. Also facilitated is the isolation of endothelial progenitor cells for research purposes such as in vitro based screening systems for testing the therapeutic impact and/or toxicity of potential treatment or culture regimes to which these cells may be exposed to. The present invention also discloses methods for isolating mesenchymal stem cells, in particular mesenchymal stem cells of fetal and/or maternal origin.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: June 29, 2021
    Assignee: The University of Queensland
    Inventors: Jatin Patel, Paul Kiarash Khosrotehrani, Nicholas Maxwell Fisk
  • Patent number: 11033507
    Abstract: The invention relates, in part, to a method of producing silica vesicles including under controlled conditions to thereby heavily influence the morphology and characteristics of the vesicles. The vesicles are shown to be effective as delivery agents for chemical and biological agents. They are also shown to be useful in methods of treatment and as components of an immunogenic composition.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 15, 2021
    Assignee: The University of Queensland
    Inventors: Chengzhong Yu, Neena Mitter, Jun Zhang
  • Patent number: 11027831
    Abstract: A safety rotor system for an aircraft including a flight rotor that is rotationally driven by a drive, the system including: a safety rotor that is rotationally driven during rotation of the flight rotor, the safety rotor including one or more safety members traversing a path outward of the flight rotor so that an object approaching the flight rotor through the path contacts one of the safety members before contacting the flight rotor, wherein the safety rotor decelerates when one of the safety members contacts an object; a sensor for detecting rotation of the safety rotor; and a controller configured to: determine, using the sensor, a deceleration of the safety rotor corresponding to one of the safety members contacting an object; and cause the rotation of the flight rotor to cease in response to detecting the deceleration of the safety rotor.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: June 8, 2021
    Assignee: The University of Queensland
    Inventor: Pauline Edith Iyan Pounds
  • Patent number: 11021408
    Abstract: A nanoparticulate fertilizer is provided. The fertilizer may comprise water soluble nanoparticles having a contact area to total surface area ratio greater than 1:4. The nanoparticles may have an overall positive surface charge in water. The fertilizer may be suitable for application as a seed coat. Also provided is a method of applying a seed coat, and a method of fertilizing a plant.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: June 1, 2021
    Assignee: The University of Queensland
    Inventors: Longbin Huang, Anh Van Nguyen, Victor Rudolph, Gordon Xu
  • Patent number: 10947271
    Abstract: The invention concerns agents with antibacterial activity, their production and use in the treatment of bacterial infections in animals, including man. The agents are derivatives of vancomycin-type antibiotics, of structure X—W-L-V, wherein X is hydrogen, acetyl or a lipophilic membrane-insertive element, W is a basic peptide or basic amino acid; L is a linking group and V is a glycopeptide moiety which inhibits peptidoglycan biosynthesis in bacteria.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: March 16, 2021
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Matthew Cooper, Mark Blaskovich
  • Patent number: 10933049
    Abstract: The present invention discloses the use of a complement 3a receptor (C3aR) antagonist and a mobilizer of hematopoietic stem cells and/or progenitor cells in methods and compositions for stimulating or enhancing the development, mobilization, proliferation and/or differentiation of a neutrophil-containing leukocyte population that inhibits growth and/or spread of a tumor and for treating or preventing a hyperproliferative cell disorder.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: March 2, 2021
    Assignee: The University of Queensland
    Inventors: Trent Woodruff, Barbara Rolfe
  • Patent number: 10900022
    Abstract: A method is provided for simultaneously producing both nephron progenitor cells and ureteric epithelial progenitor cells including the step of contacting intermediate mesoderm cells with: fibroblast growth factor (9) and/or fibroblast growth factor (20) and optionally, one or more selected from the group consisting of. bone morphogenic protein 7; heparin: a Wnt agonist; retinoic acid; and an RA antagonist. The concentrations of Writ agonist, retinoic acid and/or RA antagonist may be manipulated to favour the relative production of nephron progenitor cells and ureteric epithelial progenitor cells. The intermediate mesoderm cells are ultimately derived from human pluripotent stem cells via a posterior primitive streak stage. The nephron progenitor cells and ureteric epithelial progenitor cells may have end uses such as for kidney repair and regeneration, bioprinting of kidneys and screening compounds for nephrotoxicity.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: January 26, 2021
    Assignee: The University of Queensland
    Inventors: Melissa Little, Minoru Takasato
  • Patent number: 10881712
    Abstract: The invention relates to disulfide-rich peptides derived from spider venom and their use, particularly as neuroprotective agents. The invention also relates to nucleic acid molecules encoding the peptides as well as constructs and host cells comprising those nucleic acid molecules.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: January 5, 2021
    Assignees: The University of Queensland, Monash University
    Inventors: Glenn Frederick King, Lachlan Douglas Rash, Irene Chassagnon, Sandy Steffany Pineda Gonzalez, Robert Edward Widdop, Claudia Ann Ireland
  • Publication number: 20200339684
    Abstract: The present disclosure relates to proteins that bind to CD83 and uses thereof, for example, in therapy, prophylaxis, diagnosis, or prognosis.
    Type: Application
    Filed: July 9, 2020
    Publication date: October 29, 2020
    Applicants: DENDROCYTE BIOTECH PTY LTD, THE UNIVERSITY OF QUEENSLAND, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Therese Ann Seldon, David John Munster, Derek Nigel John Hart, Martina Louise Jones, Trent Phillip Munro, Stephen Michael Mahler, Yu Zhou, James D. Marks
  • Patent number: 10781255
    Abstract: The present disclosure relates to proteins that bind to CD83 and uses thereof, for example, in therapy, prophylaxis, diagnosis or prognosis.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: September 22, 2020
    Assignees: DENDROCYTE BIOTECH PTY LTD, THE UNIVERSITY OF QUEENSLAND, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Therese Ann Seldon, David John Munster, Derek Nigel John Hart, Martina Louise Jones, Trent Phillip Munro, Stephen Michael Mahler, Yu Zhou, James D. Marks
  • Patent number: 10738586
    Abstract: A method for removing water from a coal seam gas well or shale gas well, the coal seam gas well or shale gas well including an outer casing into which coal seam gas and water flow near the lower region of the coal seam gas well, the method includes delivering pressurized methane into a lower region of the gas well, the pressurized methane acting to lift water from the lower region of the gas well, and cause it to flow upwards towards the surface. A system is also provided for removing water from a coal seam gas well or shale gas well. The method may be retro-fitted to existing CSG wells or shale gas wells.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: August 11, 2020
    Assignee: The University of Queensland
    Inventors: Victor Rudolph, Mahshid Firouzi, Brent Greenway