Abstract: Describes are methods of contacting printing with a shape-memory stamp. For example, disclosed herein are methods of patterning thin films using shape memory contact printing.

Abstract: An apparatus measures the transverse profile of vectorial optical field beams, including both the phase and the polarization spatial profile. The apparatus contains a polarization separation module, a weak perturbation module, and a detection module. Characterizing the transverse profile of vector fields provides an optical metrology tool for both fundamental studies of vectorial optical fields and a wide spectrum of applications, including microscopy, surveillance, imaging, communication, material processing, and laser trapping.

Abstract: Described are shape-memory polymers that have a composite prepolymer crosslinked with a stoichiometric amount of a multifunctional crosslinker, the composite prepolymer having a branched or telechelic prepolymer having a low polydispersity reacted with a non-crystalline chain extender. Also described are methods of making shape-memory polymers by reacting a branched or telechelic prepolymer having a low polydispersity with a non-crystalline chain extender to form a composite prepolymer, and crosslinking a stoichiometric amount of a multifunctional crosslinker with the composite prepolymer, thereby forming the shape-memory polymer.

Abstract: An apparatus measures the transverse profile of vectorial optical field beams, including both the phase and the polarization spatial profile. The apparatus contains a polarization separation module, a weak perturbation module, and a detection module. Characterizing the transverse profile of vector fields provides an optical metrology tool for both fundamental studies of vectorial optical fields and a wide spectrum of applications, including microscopy, surveillance, imaging, communication, material processing, and laser trapping.

Abstract: Disclosed are methods for treating an individual infected with a retrovirus that comprise administering to the individual effective amounts of a mixed lineage kinase inhibitor and antiretroviral drug. In further aspects, disclosed are methods for treating an individual infected with a retrovirus that comprises administering an antiretroviral drug formulated into a crystalline nanoparticle comprising a surfactant, and a MLK inhibitor. Still further disclosed are methods for treating an individual infected with a retrovirus that comprises administering a composition comprising both an antiretroviral and MLK inhibitor formulated into a crystalline nanoparticle, which comprises a surfactant. Still further disclosed are compositions that comprise an antiretroviral drug, a MLK inhibitor, and a surfactant, wherein the composition is a crystalline nanoparticle. Compostions comprising MLK inhibitors with other drugs in nanoparticulate form, and methods of there use, are also disclosed.

Abstract: Described are shape-memory polymers that have a branched or telechelic prepolymer having a low polydispersity crosslinked with a stoichiometric amount of a multifunctional crosslinker. Also described are methods of making shape-memory polymers by crosslinking a stoichiometric amount of a multifunctional crosslinker with a branched or telechelic prepolymer having a low polydispersity. Methods of measuring the energy storage capacity of a shape-memory polymer are also disclosed.

Abstract: A loudspeaker system composed of a flexible panel with an affixed array of force actuators, a signal processing system, and interface electronic circuits is described. The system described is capable of creating a pattern of standing bending waves at any location on the panel and the instantaneous amplitude, velocity, or acceleration of the standing waves can be controlled by an audio signal to create localized acoustic sources at the selected locations in the plane of the panel.

Abstract: The invention provides novel pharmaceutical compositions and methods for treating newborns in need of enhanced cardiac function, in particular, newborns suffering from cardiomyopathy, or a related disease or condition.

Abstract: Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.

Abstract: Methods and compositions for producing 1-butanol are described herein. In some examples, the methods can comprise, contacting a reactant comprising ethanol with a catalyst system, thereby producing a product comprising 1-butanol. The catalyst system can comprise, for example, an iridium catalyst and a nickel, copper, and/or zinc catalyst. The nickel, copper, and zinc catalysts can comprise nickel, copper, and/or zinc and a sterically bulky ligand.

Abstract: Methods and compositions for depositing a monolayer onto a surface of a substrate are described. The method can include contacting the surface with a vapor phase comprising a carbene source, and reacting a carbene group from the carbene source with a functional group on the surface, to obtain a covalently bound monolayer on the surface of the substrate. The carbene source can be a diazirine compound. The functional group on the surface can be a C—H containing group, a Si—H containing group, among others, or combinations thereof. The method can further involve removing physisorbed molecules from the surface of the substrate.

Abstract: Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. The compounds include substituted pyrrolo[2,3-b]pyridines having Formula IX Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.

Abstract: Compositions and methods for separating double-stranded nucleic acids out of a mixture comprising single-stranded nucleic acids and/or dNTPs and/or enzymes. The method uses spatially inhomogeneously functionalized nanoporous materials. For example, the compositions and methods of the present invention can be used to purify DNA amplification reaction products.

Abstract: Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.

Abstract: Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.

Abstract: Disclosed herein are systems and methods for removing reverberation from signals. The systems and methods can be applicable to audio signals, for example, to voice, musical instrument sounds, and the like. Signals such as the vowel sounds in speech and the sustained portions of many musical instrument sounds can be composed of a fundamental frequency component and a series of harmonically related overtones. The systems and methods can exploit the intrinsically high degree of mutual correlation among the overtones. When such signals are passed through a reverberant channel, the degree of mutual correlation among the partials can be reduced. An inverse channel filter for the removal of reverberation can be found by employing an adaptive filter technique that maximizes the cross-correlation among signal overtones.

Abstract: Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.

Abstract: Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. The compounds include substituted pyrrolo [2,3b]pyridines having Formula IX Also provided are pharmaceutical compositions, methods of preparing the compounds, synthetic intermediates, and methods of using the compounds, independently or in combination with other therapeutic agents, for treating diseases and conditions which are affected by Mixed Lineage Kinase inhibition. Also provided are methods of treatment of neuropsychiatric disorders which comprise the inhibition of Mixed Lineage Kinases.

Abstract: There is provided an implantable pressure monitor having a fluid sack in contact with a body part of a patient where the fluid sack is retained to the body part by a pressure monitor housing that may have various attachment means. The fluid sack is filled with a liquid such as silicone oil. The pressure monitor housing has an opening that provides access to a fistula with a fluid valve that terminates through the fluid sack. A fiber optic pressure sensor is in contact with the liquid in the fluid sack by way of the fistula and fluid valve. In some embodiments of the present invention, an electronics module is incorporated with the implantable pressure monitor to provide telemetry, power, and the like.

Abstract: Compositions and methods for separating double-stranded nucleic acids out of a mixture comprising single-stranded nucleic acids and/or dNTPs and/or enzymes. The method uses spatially inhomogenously functionalized nanoporous materials. For example, the compositions and methods of the present invention can be used to purify DNA amplification reaction products.