Patents Assigned to The University of South Carolina
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Patent number: 12288320Abstract: Described herein are systems and methods for imaging the top surface of a fuel pellet to observe the formation of radial cracks employing resistive heating to volumetrically heat the fuel pellet, but instead of passing the current axially through the pellet, electrodes were placed on the sides of a single pellet to pass the current transversely across the pellet allowing for an unobstructed view of the top surface of the pellet.Type: GrantFiled: October 21, 2021Date of Patent: April 29, 2025Assignee: University of South CarolinaInventors: Travis Knight, Sobhan Patnaik, Theodore Besmann, Elwyn Roberts
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Patent number: 12284514Abstract: Described herein are methods, techniques and systems for a user to conduct authentication via inertial measurement unit data collected by the user's smartphone and video data collected by a drone recording the user operations for mutual authentication, as well as to prevent attacks of the authentication data, wherein correlation can be easily extended to using other information, such as noises, illuminance, GPS, and how the phone flashlight flashes.Type: GrantFiled: June 30, 2022Date of Patent: April 22, 2025Assignee: University of South CarolinaInventors: Qiang Zeng, Lannan Luo
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Patent number: 12281080Abstract: Disclosed herein are quinoline-based compounds and method for inhibiting CDK8 or CDK19 for the intervention in diseases, disorders, and conditions. The quinoline-based composition comprise substituents at quinoline ring positions 4 and 6, wherein the substituent at position 4 is selected from a substituted or unsubstituted arylalkylamine or a substituted or unsubstituted arylhetrocyclylamine. Pharmaceutical compositions comprising the substituted quinoline compositions, methods of inhibiting CDK8 or CDK19, and methods of treating CDK8/19-associated diseases, disorders, or conditions are also disclosed.Type: GrantFiled: May 25, 2021Date of Patent: April 22, 2025Assignees: University of South Carolina, Senex Biotechnology, Inc.Inventors: Igor Roninson, Campbell McInnes, Mengqian Chen, Li Zhang, Jing Li
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Publication number: 20250116633Abstract: Employing methodologies and systems to detect damage initiation and growth inside a composite material (matrix cracking, delamination, fiber break, fiber pullout, etc.) wherein damage produces high-frequency acoustic emission (AE) waves that are transported to recording sensors along with relatively lower frequency waves representing the flexural deformation of the impacted composite structure.Type: ApplicationFiled: May 13, 2024Publication date: April 10, 2025Applicant: University of South CarolinaInventors: Victor Giurgiutiu, Robin James, Roshan Joseph
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Patent number: 12258586Abstract: Embodiments of the invention include systems and media for mammalian cell culture that enhance cell viability which enables biological assays and quantitative studies in tissues such as skin explants. Certain embodiments may be used in coordination with each other or may be practiced separately. An exemplary embodiment of the invention is a culture medium that includes Dulbecco's Modified Eagle's Medium, X-VIVO medium, and subcutaneous adipocyte medium. In one embodiment the culture medium includes approximately 30-60% Dulbecco's Modified Eagle's Medium by volume, approximately 30-60% X-VIVO medium by volume, and approximately 2.5-15% subcutaneous adipocyte medium by volume. Certain embodiments of the culture medium can also include recombinant human stem cell factor. Embodiments of the invention disclosed here are not limited to the brands described and encompass equivalents, as well as combinations, of the individual chemical components that make up the media described herein.Type: GrantFiled: October 21, 2019Date of Patent: March 25, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Carole A. Oskeritzian, Alena P. Chumanevich
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Patent number: 12253521Abstract: Methods and systems for detection of precancerous colorectal cancerous lesions and early stage colorectal cancer are described. The methods and systems include examination of a rectal cell sample for the presence of mast cells in a field effect detection regime. The methods can incorporate swab-based cell collection, optionally storage and transportation of a cell sample, and/or computer-aided diagnosis.Type: GrantFiled: June 29, 2023Date of Patent: March 18, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Carole A. Oskeritzian, Franklin Berger, Alena P. Chumanevich, John W. Fuseler, Nabihah I. Kumte, Ahmed Aladhami
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Patent number: 12244373Abstract: Described herein are systems, methods and devices for implementing a temperature-aware, multi-antenna scheduler that cools mmWave devices by preventing heat buildup via switching or distributing a data stream to other redundant antennas, allowing for dissipation of heat as well as providing reliable connectivity.Type: GrantFiled: February 9, 2023Date of Patent: March 4, 2025Assignee: University of South CarolinaInventors: Sanjib Sur, Moh. S. Saadat, Srihari Nelakuditi
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Patent number: 12227212Abstract: Systems, methods and devices for a computer vision-based pixel-level rail components detection system using an improved one-stage instance segmentation model and prior knowledge, aiming to inspect railway components in a rapid, accurate, and convenient fashion.Type: GrantFiled: May 26, 2021Date of Patent: February 18, 2025Assignee: University of South CarolinaInventors: Yu Qian, Feng Guo
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Patent number: 12231897Abstract: Internet of Things (IoT) devices lack conventional user interfaces, such as keyboards and displays, which make many traditional pairing approaches inapplicable. Proximity-based pairing approaches are very usable, but can be exploited by co-located malicious devices. A secure and usable pairing approach that can be applied to heterogeneous IoT devices still does not exist. The presently disclosed Universal Operation Sensing allows an IoT device to sense the user's physical operations on it without requiring inertial sensors. With this technique, a user holding a smartphone or wearing a wristband can finish pairing in seconds through some very simple operations, e.g., pressing a button or twisting a knob. A presently disclosed pairing protocol uses faithful fuzzy commitment, which is secure and usable.Type: GrantFiled: March 10, 2022Date of Patent: February 18, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventor: Qiang Zeng
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Patent number: 12227627Abstract: Novel PBI films which may be used in electrochemical cells, such as redox flow batteries, are disclosed. Additionally, disclosed herein are membranes which comprise the novel PBI films which may be free from an organic solvent, and have a tensile strength at break of at least 25 MPa after drying.Type: GrantFiled: December 11, 2023Date of Patent: February 18, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Laura A. Murdock, Lihui Wang, Fei Huang, Brian C. Benicewicz
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Patent number: 12226754Abstract: Described herein is a general scalable synthesis method for a high density of single metal atoms in a supported catalyst, supported isolated atoms featuring unique reactivity and the support materials determine the stability, electronic properties, and local environment which can be adjusted for targeted heterogeneous catalysis applications.Type: GrantFiled: November 1, 2021Date of Patent: February 18, 2025Assignee: University of South CarolinaInventors: Abolfazl Shakouri, Horie Adabi Firouzjaie, John R. Regalbuto, Christopher T. Williams, William E Mustain
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Patent number: 12208168Abstract: The present disclosure is directed to hybrid multifunctional macromers that can self-assemble to form nanoparticles for on-demand and targeted release of morphogens. Embodiments of the disclosure can include the hybrid multifunctional macromers and peptide sequences incorporated therein, self-assembled nanoparticles including the hybrid multifunctional macromers, methods for producing the hybrid multifunctional macromers and peptide sequences, and methods for treating a disease by the on-demand and targeted delivery of a compound using the hybrid multifunctional macromers.Type: GrantFiled: April 28, 2023Date of Patent: January 28, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventor: Esmaiel Jabbari
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Patent number: 12196684Abstract: Medical swabs incorporating a pH indicator in an absorbent crosslinked hydrogel matrix. The medical swabs can provide for visual monitoring of biological pH. The medical swabs can be used to monitor wounds, such as chronic wounds, burn wounds, surgical wounds, etc., as well as other biological fluids. The swabs can be used for early detection of chronic wounds and/or early detection of bacterial infections.Type: GrantFiled: May 25, 2023Date of Patent: January 14, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Ehsan Jabbarzadeh, Sara Eslambolchimoghadam
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Publication number: 20240424483Abstract: A catalyst support containing praseodymium oxide and dysprosium oxide, supported catalysts using the support, and methods of using the supported catalysts to catalyze the formation and degradation of ammonia.Type: ApplicationFiled: June 4, 2024Publication date: December 26, 2024Applicant: University of South CarolinaInventors: Samuel Drummond, Jochen Lauterbach, Jennifer Naglic
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Patent number: 12172025Abstract: A method of treating dysautonomia in a human via transcranial magnetic stimulation is provided. The method includes positioning an induction device in proximity to a head region adjacent a prefrontal cortical brain region of the human and delivering magnetic stimulation to the prefrontal cortical region of the human by applying current to the induction device at a frequency that promotes inhibition (e.g., a frequency of about 5 Hertz or less, or certain types of theta bursts). The transcranial magnetic stimulation can introduce variability and/or have a modulatory or a disinhibitory effect on an autonomic nervous system of the human. For instance, the transcranial magnetic stimulation can increase a level of heart rate variability in the human by having a positive modulatory effect on the autonomic nervous system in which autonomic balance is achieved or restored as a result of the stimulation.Type: GrantFiled: April 24, 2020Date of Patent: December 24, 2024Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Manuel Casanova, Emily Casanova, Estate Sokhadze
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Publication number: 20240416323Abstract: A catalyst including ruthenium, a promoter metal, and a second metal, optionally disposed on a support, and methods of using the catalyst to catalyze the formation of ammonia.Type: ApplicationFiled: June 4, 2024Publication date: December 19, 2024Applicant: University of South CarolinaInventors: Samuel Drummond, Jochen Lauterbach, Jennifer Naglic
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Patent number: 12170031Abstract: A cannulation simulation device and methods for using the device are described. The device is designed to teach dialysis technicians/nurses or patients to cannulate arteriovenous (AV) fistulas for hemodialysis. The simulator includes one or more artificial fistulas. The simulator includes a pad of simulated flesh that can cover the artificial fistula(s). The pad can be reversed, rotated, and replaced with thicker or thinner pads. A personal simulation device for teaching self-cannulation can include a sleeve for a limb that can carry an artificial fistula. A clinical simulation device can include a plurality of artificial fistulas held in a support. Optionally, the artificial fistulas can vibrate to simulate an actual fistula.Type: GrantFiled: December 27, 2023Date of Patent: December 17, 2024Assignees: UNIVERSITY OF SOUTH CAROLINA, PRISMA HEALTH—UPSTATEInventors: David L. Cull, Thomas B. O'Hanlan
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Publication number: 20240414563Abstract: Described herein is an over-the-air computation (OAC) scheme for a federated k-means clustering algorithm to reduce the per-round communication latency when implemented over a wireless network. The OAC scheme relies on an encoder exploiting the representation of a number in a balanced number system and computes the sum of the updates for the federated k-means via signal superposition property of wireless multiple-access channels non-coherently to eliminate the need for precise phase and time synchronization.Type: ApplicationFiled: May 21, 2024Publication date: December 12, 2024Applicant: University of South CarolinaInventor: Alphan Sahin
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Patent number: D1066509Type: GrantFiled: August 17, 2022Date of Patent: March 11, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Trenton Agrelius, Matthew Bruner
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Patent number: D1066510Type: GrantFiled: August 17, 2022Date of Patent: March 11, 2025Assignee: UNIVERSITY OF SOUTH CAROLINAInventors: Trenton Agrelius, Matthew Bruner