Patents Assigned to The University of South Carolina
  • Patent number: 12288320
    Abstract: Described herein are systems and methods for imaging the top surface of a fuel pellet to observe the formation of radial cracks employing resistive heating to volumetrically heat the fuel pellet, but instead of passing the current axially through the pellet, electrodes were placed on the sides of a single pellet to pass the current transversely across the pellet allowing for an unobstructed view of the top surface of the pellet.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: April 29, 2025
    Assignee: University of South Carolina
    Inventors: Travis Knight, Sobhan Patnaik, Theodore Besmann, Elwyn Roberts
  • Patent number: 12284514
    Abstract: Described herein are methods, techniques and systems for a user to conduct authentication via inertial measurement unit data collected by the user's smartphone and video data collected by a drone recording the user operations for mutual authentication, as well as to prevent attacks of the authentication data, wherein correlation can be easily extended to using other information, such as noises, illuminance, GPS, and how the phone flashlight flashes.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: April 22, 2025
    Assignee: University of South Carolina
    Inventors: Qiang Zeng, Lannan Luo
  • Patent number: 12281080
    Abstract: Disclosed herein are quinoline-based compounds and method for inhibiting CDK8 or CDK19 for the intervention in diseases, disorders, and conditions. The quinoline-based composition comprise substituents at quinoline ring positions 4 and 6, wherein the substituent at position 4 is selected from a substituted or unsubstituted arylalkylamine or a substituted or unsubstituted arylhetrocyclylamine. Pharmaceutical compositions comprising the substituted quinoline compositions, methods of inhibiting CDK8 or CDK19, and methods of treating CDK8/19-associated diseases, disorders, or conditions are also disclosed.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: April 22, 2025
    Assignees: University of South Carolina, Senex Biotechnology, Inc.
    Inventors: Igor Roninson, Campbell McInnes, Mengqian Chen, Li Zhang, Jing Li
  • Publication number: 20250116633
    Abstract: Employing methodologies and systems to detect damage initiation and growth inside a composite material (matrix cracking, delamination, fiber break, fiber pullout, etc.) wherein damage produces high-frequency acoustic emission (AE) waves that are transported to recording sensors along with relatively lower frequency waves representing the flexural deformation of the impacted composite structure.
    Type: Application
    Filed: May 13, 2024
    Publication date: April 10, 2025
    Applicant: University of South Carolina
    Inventors: Victor Giurgiutiu, Robin James, Roshan Joseph
  • Patent number: 12258586
    Abstract: Embodiments of the invention include systems and media for mammalian cell culture that enhance cell viability which enables biological assays and quantitative studies in tissues such as skin explants. Certain embodiments may be used in coordination with each other or may be practiced separately. An exemplary embodiment of the invention is a culture medium that includes Dulbecco's Modified Eagle's Medium, X-VIVO medium, and subcutaneous adipocyte medium. In one embodiment the culture medium includes approximately 30-60% Dulbecco's Modified Eagle's Medium by volume, approximately 30-60% X-VIVO medium by volume, and approximately 2.5-15% subcutaneous adipocyte medium by volume. Certain embodiments of the culture medium can also include recombinant human stem cell factor. Embodiments of the invention disclosed here are not limited to the brands described and encompass equivalents, as well as combinations, of the individual chemical components that make up the media described herein.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: March 25, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Carole A. Oskeritzian, Alena P. Chumanevich
  • Patent number: 12253521
    Abstract: Methods and systems for detection of precancerous colorectal cancerous lesions and early stage colorectal cancer are described. The methods and systems include examination of a rectal cell sample for the presence of mast cells in a field effect detection regime. The methods can incorporate swab-based cell collection, optionally storage and transportation of a cell sample, and/or computer-aided diagnosis.
    Type: Grant
    Filed: June 29, 2023
    Date of Patent: March 18, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Carole A. Oskeritzian, Franklin Berger, Alena P. Chumanevich, John W. Fuseler, Nabihah I. Kumte, Ahmed Aladhami
  • Patent number: 12244373
    Abstract: Described herein are systems, methods and devices for implementing a temperature-aware, multi-antenna scheduler that cools mmWave devices by preventing heat buildup via switching or distributing a data stream to other redundant antennas, allowing for dissipation of heat as well as providing reliable connectivity.
    Type: Grant
    Filed: February 9, 2023
    Date of Patent: March 4, 2025
    Assignee: University of South Carolina
    Inventors: Sanjib Sur, Moh. S. Saadat, Srihari Nelakuditi
  • Patent number: 12227212
    Abstract: Systems, methods and devices for a computer vision-based pixel-level rail components detection system using an improved one-stage instance segmentation model and prior knowledge, aiming to inspect railway components in a rapid, accurate, and convenient fashion.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: February 18, 2025
    Assignee: University of South Carolina
    Inventors: Yu Qian, Feng Guo
  • Patent number: 12231897
    Abstract: Internet of Things (IoT) devices lack conventional user interfaces, such as keyboards and displays, which make many traditional pairing approaches inapplicable. Proximity-based pairing approaches are very usable, but can be exploited by co-located malicious devices. A secure and usable pairing approach that can be applied to heterogeneous IoT devices still does not exist. The presently disclosed Universal Operation Sensing allows an IoT device to sense the user's physical operations on it without requiring inertial sensors. With this technique, a user holding a smartphone or wearing a wristband can finish pairing in seconds through some very simple operations, e.g., pressing a button or twisting a knob. A presently disclosed pairing protocol uses faithful fuzzy commitment, which is secure and usable.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: February 18, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventor: Qiang Zeng
  • Patent number: 12227627
    Abstract: Novel PBI films which may be used in electrochemical cells, such as redox flow batteries, are disclosed. Additionally, disclosed herein are membranes which comprise the novel PBI films which may be free from an organic solvent, and have a tensile strength at break of at least 25 MPa after drying.
    Type: Grant
    Filed: December 11, 2023
    Date of Patent: February 18, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Laura A. Murdock, Lihui Wang, Fei Huang, Brian C. Benicewicz
  • Patent number: 12226754
    Abstract: Described herein is a general scalable synthesis method for a high density of single metal atoms in a supported catalyst, supported isolated atoms featuring unique reactivity and the support materials determine the stability, electronic properties, and local environment which can be adjusted for targeted heterogeneous catalysis applications.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: February 18, 2025
    Assignee: University of South Carolina
    Inventors: Abolfazl Shakouri, Horie Adabi Firouzjaie, John R. Regalbuto, Christopher T. Williams, William E Mustain
  • Patent number: 12208168
    Abstract: The present disclosure is directed to hybrid multifunctional macromers that can self-assemble to form nanoparticles for on-demand and targeted release of morphogens. Embodiments of the disclosure can include the hybrid multifunctional macromers and peptide sequences incorporated therein, self-assembled nanoparticles including the hybrid multifunctional macromers, methods for producing the hybrid multifunctional macromers and peptide sequences, and methods for treating a disease by the on-demand and targeted delivery of a compound using the hybrid multifunctional macromers.
    Type: Grant
    Filed: April 28, 2023
    Date of Patent: January 28, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventor: Esmaiel Jabbari
  • Patent number: 12196684
    Abstract: Medical swabs incorporating a pH indicator in an absorbent crosslinked hydrogel matrix. The medical swabs can provide for visual monitoring of biological pH. The medical swabs can be used to monitor wounds, such as chronic wounds, burn wounds, surgical wounds, etc., as well as other biological fluids. The swabs can be used for early detection of chronic wounds and/or early detection of bacterial infections.
    Type: Grant
    Filed: May 25, 2023
    Date of Patent: January 14, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Ehsan Jabbarzadeh, Sara Eslambolchimoghadam
  • Publication number: 20240424483
    Abstract: A catalyst support containing praseodymium oxide and dysprosium oxide, supported catalysts using the support, and methods of using the supported catalysts to catalyze the formation and degradation of ammonia.
    Type: Application
    Filed: June 4, 2024
    Publication date: December 26, 2024
    Applicant: University of South Carolina
    Inventors: Samuel Drummond, Jochen Lauterbach, Jennifer Naglic
  • Patent number: 12172025
    Abstract: A method of treating dysautonomia in a human via transcranial magnetic stimulation is provided. The method includes positioning an induction device in proximity to a head region adjacent a prefrontal cortical brain region of the human and delivering magnetic stimulation to the prefrontal cortical region of the human by applying current to the induction device at a frequency that promotes inhibition (e.g., a frequency of about 5 Hertz or less, or certain types of theta bursts). The transcranial magnetic stimulation can introduce variability and/or have a modulatory or a disinhibitory effect on an autonomic nervous system of the human. For instance, the transcranial magnetic stimulation can increase a level of heart rate variability in the human by having a positive modulatory effect on the autonomic nervous system in which autonomic balance is achieved or restored as a result of the stimulation.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: December 24, 2024
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Manuel Casanova, Emily Casanova, Estate Sokhadze
  • Publication number: 20240416323
    Abstract: A catalyst including ruthenium, a promoter metal, and a second metal, optionally disposed on a support, and methods of using the catalyst to catalyze the formation of ammonia.
    Type: Application
    Filed: June 4, 2024
    Publication date: December 19, 2024
    Applicant: University of South Carolina
    Inventors: Samuel Drummond, Jochen Lauterbach, Jennifer Naglic
  • Patent number: 12170031
    Abstract: A cannulation simulation device and methods for using the device are described. The device is designed to teach dialysis technicians/nurses or patients to cannulate arteriovenous (AV) fistulas for hemodialysis. The simulator includes one or more artificial fistulas. The simulator includes a pad of simulated flesh that can cover the artificial fistula(s). The pad can be reversed, rotated, and replaced with thicker or thinner pads. A personal simulation device for teaching self-cannulation can include a sleeve for a limb that can carry an artificial fistula. A clinical simulation device can include a plurality of artificial fistulas held in a support. Optionally, the artificial fistulas can vibrate to simulate an actual fistula.
    Type: Grant
    Filed: December 27, 2023
    Date of Patent: December 17, 2024
    Assignees: UNIVERSITY OF SOUTH CAROLINA, PRISMA HEALTH—UPSTATE
    Inventors: David L. Cull, Thomas B. O'Hanlan
  • Publication number: 20240414563
    Abstract: Described herein is an over-the-air computation (OAC) scheme for a federated k-means clustering algorithm to reduce the per-round communication latency when implemented over a wireless network. The OAC scheme relies on an encoder exploiting the representation of a number in a balanced number system and computes the sum of the updates for the federated k-means via signal superposition property of wireless multiple-access channels non-coherently to eliminate the need for precise phase and time synchronization.
    Type: Application
    Filed: May 21, 2024
    Publication date: December 12, 2024
    Applicant: University of South Carolina
    Inventor: Alphan Sahin
  • Patent number: D1066509
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: March 11, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Trenton Agrelius, Matthew Bruner
  • Patent number: D1066510
    Type: Grant
    Filed: August 17, 2022
    Date of Patent: March 11, 2025
    Assignee: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Trenton Agrelius, Matthew Bruner