Patents Assigned to The University of Tasmania
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Patent number: 11590463Abstract: A liquid-liquid mixing device (10, 210) includes a barrel (20, 220) with a liquid port (23) at or adjacent one end. A plunger assembly (30) is reciprocably moveable along an axis in the barrel (20, 220) and includes a seal member (31, 231) and an agitator (50, 250). The seal member (31, 231) is in sealingly slidable engagement with the internal wall of the barrel (20, 220) to define a variable volume chamber (24, 224) therein in communication with the liquid port. The agitator (50, 250) is reciprocably moveable in the variable volume chamber (24, 224), which agitator (50, 250) includes one or more end to end passages (54) through which liquid in the chamber (24, 224) is forced as the agitator (250) reciprocates in the chamber (24, 224).Type: GrantFiled: June 28, 2018Date of Patent: February 28, 2023Assignee: University of TasmaniaInventors: Robert Shellie, Masoomeh Tehrani Rokh, Marcel Van Den Bronk
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Publication number: 20220160272Abstract: A pen format liquid collection device includes an elongate generally tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end, and at least one liquid take-up element (30, 130, 230, 330) mounted in the housing so as to be positioned or positionable to project at the opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed. At least one retention element (230a, 330a) is supported in the housing. The at least one liquid take-up element and the at least one retention element are arranged whereby they are relatively movable into contact, and the at least one retention element is adapted on contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing. The liquid take-up element is preferably a capillary.Type: ApplicationFiled: January 28, 2022Publication date: May 26, 2022Applicant: University of TasmaniaInventors: David Charles BAILEY, Andrew GOOLEY, Florian Germain LAPIERRE, David John MELVILLE, Rod Anthony WIEBENGA, Chau Hoang Thanh NGUYEN, Eugen MEYER
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Patent number: 11278225Abstract: A pen format liquid collection device includes an elongate generally tubular housing (12, 112, 212, 312) able to be held by hand and having an opening at one end, and at least one liquid take-up element (30, 130, 230, 330) mounted in the housing so as to be positioned or positionable to project at the opening, the at least one liquid take-up element then further postionable by hand manipulation of the housing to contact a volume of liquid to thereby take-up a sample of the liquid to be analysed. At least one retention element (230a, 330a) is supported in the housing. The at least one liquid take-up element and the at least one retention element are arranged whereby they are relatively movable into contact, and the at least one retention element is adapted on contact to in turn take-up the sample and retain the sample or a component thereof for in situ analysis or later recovery while protected within the housing. The liquid take-up element is preferably a capillary.Type: GrantFiled: August 12, 2016Date of Patent: March 22, 2022Assignee: University of TasmaniaInventors: David Charles Bailey, Andrew Gooley, Florian Germain Lapierre, David John Melville, Rod Anthony Wiebenga, Chau Hoang Thanh Nguyen, Eugen Meyer
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Patent number: 11135384Abstract: Provided herein is a method for automatically controlling inspired oxygen delivery, including: receiving signals representing a plurality of input oxygen saturation (SpO2) values for a patient; generating control values based on the input SpO2 values and a target SpO2 value; and generating output inspired oxygen concentration (FiO2) values based on the control values and reference inspired oxygen concentration (rFiO2) values; wherein the control values include: immediate control values, generated based on the input SpO2 values, the target SpO2 value, and an immediate gain coefficient; accumulation control values, generated based on the input SpO2 values, the target SpO2 value, and an accumulation gain coefficient; and predictive control values, generated based on the input SpO2 values, the target SpO2 value, and a predictive gain coefficient; wherein the immediate gain coefficient is determined based on the rFiO2 value; and wherein a non-linear compensation weighting is applied to the accumulation control valType: GrantFiled: November 10, 2016Date of Patent: October 5, 2021Assignee: University of TasmaniaInventors: Timothy John Gale, Peter Anderson Dargaville
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Publication number: 20210118525Abstract: The present disclosure relates to methods and systems for assessing the risk of glaucoma in a subject. In certain embodiments, the present disclosure provide a method of assessing the risk of primary open angle glaucoma in a subject, the method comprises determining a risk score for primary open angle glaucoma in the subject on the basis of the genetic content of the subject at a plurality of selected genetic loci or markers and thereby assessing the risk of primary open angle glaucoma in the subject, wherein the selected genetic loci or markers comprise (i) genetic loci or markers having an association with glaucoma, and/or (ii) genetic loci or markers having an association with increased intraocular pressure, and/or (iii) genetic loci or markers having an association with an increased vertical cup to disk ratio, and/or (iv) genetic loci or markers having an association with a multi-trait test of glaucoma, intraocular pressure and vertical cup to disc ratio. Other embodiments are described.Type: ApplicationFiled: June 20, 2019Publication date: April 22, 2021Applicants: The Flinders University of South Australia, The Council of the Queensland Institute of Medical Research, University of Tasmania, Southern Adelaide Local Health NetworkInventors: Jamie Evan Craig, Stuart MacGregor, Alex William Hewitt
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Patent number: 10934253Abstract: The invention relates to compounds of Formula (I) and methods for their preparation. Also described are pharmaceutical compositions comprising a compound of Formula (I) and their use in the treatment or prevention of conditions associated with mitochondrial dysfunction.Type: GrantFiled: April 20, 2018Date of Patent: March 2, 2021Assignee: University of TasmaniaInventors: Nuri Güven, Jason Smith, Krystel Lee Woolley, Monila Nadikudi
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Publication number: 20200131119Abstract: The invention relates to compounds of Formula (I) and methods for their preparation. Also described are pharmaceutical compositions comprising a compound of Formula (I) and their use in the treatment or prevention of conditions associated with mitochondrial dysfunction.Type: ApplicationFiled: April 20, 2018Publication date: April 30, 2020Applicant: UNIVERSITY OF TASMANIAInventors: Nuri GÜVEN, Jason SMITH, Krystel Lee WOOLLEY, Monila NADIKUDI
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Publication number: 20200122101Abstract: A liquid-liquid mixing device (10, 210) includes a barrel (20, 220) with a liquid port (23) at or adjacent one end. A plunger assembly (30) is reciprocably moveable along an axis in the barrel (20, 220) and includes a seal member (31, 231) and an agitator (50, 250). The seal member (31, 231) is in sealingly slidable engagement with the internal wall of the barrel (20, 220) to define a variable volume chamber (24, 224) therein in communication with the liquid port. The agitator (50, 250) is reciprocably moveable in the variable volume chamber (24, 224), which agitator (50, 250) includes one or more end to end passages (54) through which liquid in the chamber (24, 224) is forced as the agitator (250) reciprocates in the chamber (24, 224).Type: ApplicationFiled: June 28, 2018Publication date: April 23, 2020Applicant: University of TasmaniaInventors: Robert SHELLIE, Masoomeh TEHRANI ROKH, Marcel VAN DEN BRONK
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Patent number: 10306883Abstract: The present invention generally relates to the use of porous polymer materials as a medium for the storage of biological samples. The present invention also relates to a method of drying and storage of biological samples on the porous polymer materials. The biological samples include blood and blood plasma samples.Type: GrantFiled: January 9, 2014Date of Patent: June 4, 2019Assignee: University of TasmaniaInventors: Emily Frances Hilder, Wei Boon Hon
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Patent number: 10100100Abstract: The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (MT), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.Type: GrantFiled: December 13, 2016Date of Patent: October 16, 2018Assignee: University of TasmaniaInventors: Vladimir Berezin, Elisabeth Bock, Milena Penkowa
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Patent number: 9683961Abstract: Disclosed are methods and systems for the simultaneous separation and detection of analytes such as anions and cations in a sample using electrophoresis, the method comprising injecting the sample into an electrophoresis system comprising two separation channels through a single sample injection port which is in fluid communication with the two separation channels, separating analytes such as the cations in a first of the two separation channels and simultaneously separation analytes such as the anions in a second of the two separation channels, and detecting the analytes separated in each of the separation channels.Type: GrantFiled: August 13, 2013Date of Patent: June 20, 2017Assignee: University of TasmaniaInventors: Michael C. Breadmore, Adam J. Gaudry, Rosanne M. Guijt
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Patent number: 9518089Abstract: The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (MT), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.Type: GrantFiled: November 21, 2013Date of Patent: December 13, 2016Assignee: University of TasmaniaInventors: Vladimir Berezin, Elisabeth Bock, Milena Penkowa
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Patent number: 9475914Abstract: The present invention generally relates to porous polymer monoliths. The present invention also relates to processes for the preparation of porous polymer monoliths, storage mediums formed from porous polymer monoliths and use thereof in the drying and storage of body fluids including blood and blood plasma samples.Type: GrantFiled: January 6, 2011Date of Patent: October 25, 2016Assignee: UNIVERSITY OF TASMANIAInventors: Paul Raymond Haddad, Emily Frances Hilder, Esme Candish, Mark A. J Bayliss
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Publication number: 20140290301Abstract: A personal cooling unit, comprising: an air inlet for receiving input air; at least one heat pump having a first surface and a second surface, and being configured to extract heat from the input air at the first surface to generate cooled output air and to transport heat to the second surface; a phase change material in thermal contact with the second surface of the heat pump; and means for conveying the cooled output air to the exterior of the unit;—wherein the phase change material undergoes a temperature-driven phase change from a first phase to a second phase, so that when at least a portion of the phase change material is in the first phase, the phase change material absorbs heat from the second surface until all of the phase change material has changed to the second phase; and wherein the phase change material has a phase transition temperature which is at least about 28° C.Type: ApplicationFiled: June 27, 2012Publication date: October 2, 2014Applicant: University of TasmaniaInventor: Teen Onn Law
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Publication number: 20140179614Abstract: The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (MT), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.Type: ApplicationFiled: November 21, 2013Publication date: June 26, 2014Applicant: University of TasmaniaInventors: Vladimir Berezin, Elisabeth Bock, Milena Penkowa
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Publication number: 20140127669Abstract: The present invention generally relates to the use of porous polymer materials as a medium for the storage of biological samples. The present invention also relates to a method of drying and storage of biological samples on the porous polymer materials. The biological samples include blood and blood plasma samples.Type: ApplicationFiled: January 9, 2014Publication date: May 8, 2014Applicant: UNIVERSITY OF TASMANIAInventors: Emily Frances HILDER, Wei Boon HON
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Patent number: 8691765Abstract: A method of stimulating neuronal growth or repair comprising exposing a target neuron or neuronal area to a solution of the metallothionein isoform MT-IIA.Type: GrantFiled: June 13, 2003Date of Patent: April 8, 2014Assignee: University of TasmaniaInventors: Adrian Keith West, Meng Inn Chuah, James Clement Vickers, Roger Steven Chung
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Patent number: 8618060Abstract: The present invention relates to neural cell survival, differentiation and proliferation promoting peptide fragments derived from metallothioneins (MT), pharmaceutical compositions comprising said peptide fragments and uses thereof for treatment of diseases and conditions where the effects of stimulating neural cell proliferation, differentiation and/or survival, and/or stimulating neural plasticity associated with learning and memory are beneficial for treatment.Type: GrantFiled: February 12, 2007Date of Patent: December 31, 2013Assignee: University of TasmaniaInventors: Vladimir Berezin, Elisabeth Bock, Milena Penkowa
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Publication number: 20080019916Abstract: A method of screening compounds for the ability to increase capillary blood flow, the method comprising: (a) taking a first measurement of capillary blood flow in a subject; (b) administering a compound to said subject; (c) taking a second measurement of capillary blood flow in said subject, and (d) comparing said first and second measurements, wherein a positive difference between said first and second measurements indicate the ability of said compound to increase capillary blood flow.Type: ApplicationFiled: July 6, 2007Publication date: January 24, 2008Applicant: University of TasmaniaInventors: Michael Clark, Stephen Rattigan
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Patent number: 7193417Abstract: Bi-planar coil assemblies are disclosed which have DSV's whose centers are offset by distances D from the origins of x,y,z-coordinate systems, where said origins of x,y,z-coordinate systems are coincident with the geometric centers of the coils. The distances D can be of the order of 10-20 centimeters or more. The bi-planar coil assemblies can be used in MRI applications to reduce the feeling of claustrophobia experienced by some subjects. The assemblies also can facilitate the imaging of various joints, including the wrist, elbow, ankle, or knee.Type: GrantFiled: November 15, 2004Date of Patent: March 20, 2007Assignees: The University of Queensland, The University of TasmaniaInventors: Lawrence Kennedy Forbes, Stuart Crozier