Patents Assigned to The University of Tennessee Research Foundation
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Publication number: 20250145470Abstract: This application relates to the development and use of lignin-based carbon materials which can be used for energy storage and environmental applications. Included are methods of preparing microporous activated carbon having a controlled, often high surface area and a controlled often high mesopore ratio, and a method of preparing carbon dots, for example carbon quantum dots.Type: ApplicationFiled: November 14, 2024Publication date: May 8, 2025Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Lu YU, David Paul Harper, David Keffer
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Patent number: 12294294Abstract: A power conversion system including a triple active bridge (TAB) is provided. The system includes a power factor correction (PFC) module and a three port converter (TPC) module, with no post-regulation or additional stages required. The TPC module includes an OBC full-bridge and an APM full-bridge, each being inductively coupled to the output of the PFC full-bridge, thereby forming the TAB. The OBC full-bridge is adapted to convert an AC input into a high-voltage DC output for a high-voltage battery, and the APM full-bridge is adapted to convert an AC input into a low-voltage DC output for a low-voltage battery. The power conversion system can accept a single-phase AC input and a three-phase AC input, has a lower current stress as compared to prior art TPCs, and freely transfers power from among any ports.Type: GrantFiled: May 25, 2021Date of Patent: May 6, 2025Assignees: Hella Corporate Center USA, Inc., University of Tennessee Research FoundationInventors: Liyan Zhu, Alan W. Brown, Hua Bai, Lukas Michael Keuck
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Patent number: 12289872Abstract: Approaches, techniques, and mechanisms are disclosed for packaging electric power components. A power module comprises: a three-dimensional (3D) cooling structure that has a plurality of planar sides; a first set of mountable power components that are mounted on a first planar side in the plurality of planar sides of the 3D cooling structure; a second set of mountable power components that are mounted on a second planar side in the plurality of planar sides of the 3D cooling structure. The second planar side represents an opposing side, of the 3D cooling structure, to the first planar side. The 3D cooling structure includes an interior space containing one or more cooling channels in which cooling fluid is to flow. The interior space of the 3D cooling structure is spatially surrounded by other planar sides in the plurality of planar sides in combination with the first and second planar sides.Type: GrantFiled: July 13, 2022Date of Patent: April 29, 2025Assignees: VOLKSWAGEN AKTIENGESELLSCHAFT, University of Tennessee Research FoundationInventors: Rüdiger Kusch, Yue Sun, Hua Bai, Hendrik Gerth
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Publication number: 20250127160Abstract: Stable nanoemulsions of a terpene-rich cannabidiol by-product (TP) and/or its distillate (DTP) can be used to effectively make pesticides, herbicides, and other bioactive products. A terpene-rich by-product (TP) can be provided, suitably by isolation from a commercial cannabidiol production process. The enriched terpene distillate (DTP) can be obtained from steam distillation of some or all of the TP. The TP and/or DTP can be combined with a surfactant to form an emulsion, which can then be sonicated to form the stable nanoemulsion. It has been discovered that the formulation of stable nanoemulsions using the terpene by-products as the lipophilic phase can effectively deliver desired levels of bioactivity while overcoming or mitigating the known drawbacks of high lipophilicity, high volatility, and propensity to thermal and oxidative degradation, all of which can lead to reduced efficacy.Type: ApplicationFiled: October 15, 2024Publication date: April 24, 2025Applicant: University of Tennessee Research FoundationInventors: Tong Wang, Kimberly D. Gwinn, Tao Fei, Zachariah R. Hansen, Duy Trinh
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Publication number: 20250118481Abstract: A coil structure for near-field wireless power transfer, integrating the traditional inductor and external capacitor structure into one single coil and forming a series resonance. The series resonance is achieved by a terminal connection and layering method. The electric field is canceled via a distributed turn-to-turn interleaving structure. With the integrated capacitor, the costs and space of a resonant capacitor can be saved. With the canceled electric field, the interference with neighboring components, such as touch-screen, can be reduced. Other benefits can include low-profile and fabrication convenience based on RGB technology. This coil can be useful for both consumer electronics and electric vehicle wireless charging.Type: ApplicationFiled: May 2, 2023Publication date: April 10, 2025Applicant: University of Tennessee Research FoundationInventors: Daniel Jes Costinett, Jie Li, Ruiyang Qin
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Patent number: 12264195Abstract: Provided herein are modified immunoglobulins comprising an amyloid reactive peptide joined to an antibody, as well as humanized antibodies that bind to human amyloid fibrils and antibody-peptide fusion proteins. Also provided herein are methods of treating amyloid-based diseases by administering a modified immunoglobulin, humanized antibody, or antibody-peptide fusion protein.Type: GrantFiled: May 9, 2024Date of Patent: April 1, 2025Assignees: Attralus, Inc, University of Tennessee Research FoundationInventors: Jonathan S. Wall, James S. Foster, Spencer Guthrie
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Publication number: 20250102686Abstract: Codoped sodium-doped cesium iodide scintillators are described. The codoping can alter one or more optical and/or scintillation property of the scintillator material. For example, the codoping can increase scintillation light yield and/or decrease scintillation decay time. Radiation detectors comprising the scintillators, methods of detecting high energy radiation using the radiation detectors, and methods of altering one or more scintillation and/or optical properties of a cesium iodide scintillator are also described.Type: ApplicationFiled: March 31, 2023Publication date: March 27, 2025Applicant: University of Tennessee Research FoundationInventors: Everett Michael Cavanaugh, Charles L. Melcher, Kimberly Shay Pestovich, Luis Manuel Stand Stracuzzi
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Publication number: 20250091254Abstract: A process of preparing carbon fiber reinforced polymer (CFRP) intermediate products is described wherein carbon fiber tows, such >50 K or 100K textile grade carbon fiber tows, are spread and contacted with a sheet of molten polymer resin. Also described is a system for preparing CFRP intermediate products, such as continuous tapes, and the CFRP intermediate products themselves.Type: ApplicationFiled: June 6, 2022Publication date: March 20, 2025Applicant: University of Tennessee Research FoundationInventors: Uday Kumar Vasant Vaidya, Joseph Michael Gauspohl, Saurabh Prakash Pethe, George Ervin Husman Ervin Husman
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Patent number: 12252826Abstract: A method of preparing an electret by saturating a nonwoven fabric with a liquid, such as water, and removing the liquid via suction to generate charges by friction between the fabric fibers and the liquid is described. The saturating can be carried out, for example, by impinging the bottom side of the fabric with a jet or jets of water while the fabric is being pulled under a solid roller. Excess water can also be applied during a water quenching step of a meltblowing or spunbonding process. An apparatus for preparing an electret according to the presently disclosed methods is also described.Type: GrantFiled: May 17, 2019Date of Patent: March 18, 2025Assignee: University of Tennessee Research FoundationInventor: Peter Ping-Yi Tsai
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Publication number: 20250051503Abstract: ?-Olefin maleic acid copolymers and ?-olefin-co-maleimide copolymers have the CH2—CH of the ?-olefin in the backbone of the copolymer with the maleic acid or maleimide and the remainder thereof extending from the backbone. The ?-olefin having the formula CH2— CH—(CH2)X-R1, and x being in the range of 1 to 19, y and z have a ratio in a range of 0.25: 1 to 8: 1, and n R1 yields a copolymer having an average molecular weight of less than 500 kg/mol. R1 (and R2 in the case of the ?-olefin-co-maleimide copolymers) is/are selected from a diverse group of moieties. The ?-olefin maleic acid copolymers and ?-olefin-co-maleimide copolymers each form lipid particles where the lipid can be from a galactolipid rich membrane of a cyanobacterium.Type: ApplicationFiled: December 8, 2022Publication date: February 13, 2025Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Brian LONG, Nathan G. BRADY, Barry D. BRUCE, Cameron Edward Workman
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Patent number: 12215086Abstract: This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors. R-isomers, and non-hydroxylated and/or non-chiral propenamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic to or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.Type: GrantFiled: January 24, 2022Date of Patent: February 4, 2025Assignee: University of Tennessee Research FoundationInventors: Ramesh Narayanan, Duane D. Miller, Thamarai Ponnusamy, Dong-Jin Hwang, Yali He
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Patent number: 12205739Abstract: A method for producing a bonded magnet, comprising: (i) low-shear compounding of a thermoplastic polymer and magnetic particles to form an initial homogeneous mixture thereof; (ii) feeding the initial homogeneous mixture into a plasticator comprising a low-shear single screw rotating unidirectionally toward a die orifice and housed within a heated barrel to result in heating of the initial homogeneous mixture until the thermoplastic polymer melts and forms a further homogeneous mixture, wherein said further homogeneous mixture is transported within threads of the single screw towards the die orifice and exits the die orifice as a solid pellet; (iii) conveying the solid pellet into a mold and compression molding the pellet in the mold, to form the bonded magnet, wherein the bonded magnet possesses a magnetic particle loading of at least 80 vol % and exhibits one or more magnetic properties varying by less than 5% throughout the bonded magnet.Type: GrantFiled: November 18, 2021Date of Patent: January 21, 2025Assignees: UT-Battelle, LLC, University of Tennessee Research FoundationInventors: Uday Kumar Vaidya, Mariappan Parans Paranthaman, Vlastimil Kunc, Ahmed A. Hassen
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Patent number: 12202815Abstract: This invention is directed to selective androgen receptor degrader (SARD) compounds including heterocyclic rings and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedys disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.Type: GrantFiled: September 5, 2019Date of Patent: January 21, 2025Assignee: University of Tennessee Research FoundationInventors: Ramesh Narayanan, Duane D. Miller, Yali He, Dong-Jin Hwang, Thamarai Ponnusamy
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Publication number: 20250023059Abstract: The presently disclosed subject matter relates to devices, systems, and methods for fabricating a solid polymer electrolyte electrode assembly are provided. One or more electrode for a solid polymer electrolyte electrode assembly includes a porous substrate configured as a liquid/gas diffusion layer and an ionomer-free catalyst coated on the substrate.Type: ApplicationFiled: August 16, 2022Publication date: January 16, 2025Applicant: University of Tennessee Research FoundationInventors: Feng Yuan Zhang, Lei Ding, Kui Li, Zhiqiang Xie, Weitian Wang, Shule Yu
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Patent number: 12187720Abstract: The present invention relates to novel compounds having anti-cancer activity, methods of making these compounds, and their use for treating cancer and drug-resistant tumors, e.g. melanoma, metastatic melanoma, drug resistant melanoma, prostate cancer and drug resistant prostate cancer.Type: GrantFiled: July 8, 2021Date of Patent: January 7, 2025Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Wei Li, Duane D Miller, Kinsie E. Arnst, Dong-Jin Hwang
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Publication number: 20240421599Abstract: In examples, provided are decentralized control methods and apparatus for controlling an output of an inverter. Also provided are decentralized control methods and apparatus for controlling demand in islanded microgrids operating with an insufficient distributed energy resource system (DER) power supply. The provided control methods and apparatus can include a power regulator and a voltage-frequency regulator configured to generate supplementary inputs to control the inverter. The power regulator can control an output of the inverter according to a real-time capacity constraint of the DER. The voltage-frequency regulator can control the output of the inverter in a manner that mitigates a voltage-frequency deviation, such as by leveraging load sensitivity.Type: ApplicationFiled: June 17, 2024Publication date: December 19, 2024Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Fangxing Li, Buxin She, Jinning Wang, Hantao Cui, Rui Bo
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Patent number: 12157845Abstract: A self-healing adhesive composition comprising a homogeneous mixture of: (i) a self-healing polymer containing hydrogen bonding groups or long-chain alkyl groups, wherein said hydrogen bonding groups comprise hydrogen bond donating groups and hydrogen bond accepting groups, and wherein said long-chain alkyl groups contain at least four carbon atoms; and (ii) an extrudable adhesive polymer base having a curable property and no self-healable property; wherein component (i) is present in the self-healing adhesive composition in an amount of at least 10 wt % and up to 70 wt % of the total of components (i) and (ii). Also described herein is a method of sealing a space (e.g., crack, gap, or pores) in a substrate material by at least partially filling the space with the self-healing adhesive composition described above and permitting the self-healing adhesive composition to harden over time without applying an external stimulus to induce hardening.Type: GrantFiled: December 10, 2020Date of Patent: December 3, 2024Assignees: UT-Battelle, LLC, University of Tennessee Research FoundationInventors: Diana Hun, Pengfei Cao, Tomonori Saito, Zhen Zhang, Bingrui Li, Natasha Ghezawi
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Patent number: 12157896Abstract: The invention relates to genes which may be utilized to induce resistance to soybean cyst nematode (SCN). More specifically the present disclosure provides genes that, when inactivated or overexpressed in a plant, particularly, a soybean plant, can confer upon the plant resistance to SCN. Methods of using these genes to obtain plants, particularly, soybean plants, that are resistant to SCN are also provided.Type: GrantFiled: September 27, 2019Date of Patent: December 3, 2024Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Tarek Abdelfattah Hewezi, Aditi Rambani, Vincent R. Pantalone, J. Hollis Rice
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Patent number: 12157765Abstract: Provided herein are modified immunoglobulins comprising an amyloid reactive peptide joined to an antibody, as well as humanized antibodies that bind to human amyloid fibrils and antibody-peptide fusion proteins. Also provided herein are methods of treating amyloid-based diseases by administering a modified immunoglobulin, humanized antibody, or antibody-peptide fusion protein.Type: GrantFiled: May 9, 2024Date of Patent: December 3, 2024Assignees: Attralus, Inc., UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONInventors: Jonathan S. Wall, James S. Foster, Spencer Guthrie
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Patent number: D1071046Type: GrantFiled: February 10, 2023Date of Patent: April 15, 2025Assignee: University of Tennessee Research FoundationInventor: Erkan Kaplanoglu