Abstract: The present application provides polynucleotides, compositions thereof and methods of treating feline herpes virus infections. In certain embodiments, the polynucleotides and compositions thereof can be used to reduce replication of feline herpes simplex virus 1 (FHV-1) in vivo and/or in vitro.
Type:
Application
Filed:
February 12, 2009
Publication date:
August 13, 2009
Applicant:
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC.
Abstract: Novel methods of synthesizing heteroatom-containing chiral porphyrins and chiral metalloporphyrins and the novel chiral porphyrins and chiral metalloporphyrins themselves are disclosed. Metal complexes of the chiral porphyrins are prepared in high yields and shown to be active catalysts for highly enantioselective and diastereoselective cyclopropanation, aziridination, and epoxidation of alkenes under a practical one-pot protocol.
Type:
Grant
Filed:
October 18, 2004
Date of Patent:
August 26, 2008
Assignee:
The University of Tennessee Research Foundation, Inc.
Inventors:
X. Peter Zhang, Ying Chen, Guang-yao Gao