Abstract: A method of treating cancer can include administering a therapeutically effective amount of a composition comprising a soluble protein fraction obtained from epidermal gel secretions of catfish to a patient in need thereof. The soluble protein fraction can include soluble proteins and lipids from the epidermal gel secretions of catfish. The soluble protein fraction can include about 87% of the soluble proteins and about 13% of the lipids. The cancer can include at least one of liver cancer and pancreatic cancer. The composition can be administered by intraperitoneal (IP) or sub-cutaneous (SC) injection.
Type:
Application
Filed:
March 5, 2019
Publication date:
September 10, 2020
Applicant:
THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER
Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
Type:
Application
Filed:
August 23, 2013
Publication date:
March 13, 2014
Applicant:
Institute For Applied Cancer Science/The University of Texas MD Anderson Cancer Center
Inventors:
Philip Jones, Maria Emilia DiFrancesco, Alessia Petrocchi, Joe Marszalek, Gang Liu, Zhijun Kang, Chris Carroll, Timothy McAfoos, Barbara Czako
Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
Type:
Application
Filed:
August 23, 2013
Publication date:
March 6, 2014
Applicant:
Institute For Applied Cancer Science/The University of Texas MD Anderson Cancer Center
Inventors:
Philip Jones, Maria Emilia DiFrancesco, Alessia Petrocchi, Christopher L. Carroll, Joe Marszalek, Barbara Czako, Ryan Johnson, Jay Theroff
Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of HIF pathway activity for the treatment or prevention of cancer and other hypoxia-mediated diseases.
Type:
Application
Filed:
August 23, 2013
Publication date:
February 27, 2014
Applicant:
Institute For Applied Cancer Science/The University of Texas MD Anderson Cancer Center
Inventors:
Philip Jones, Maria Emilia DiFrancesco, Alessia Petrocchi, Joe Marszalek, Gang Liu
Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
Type:
Application
Filed:
December 29, 2008
Publication date:
November 4, 2010
Applicants:
New Chapter Inc., The University of Texas MD Anderson Cancer Center
Inventors:
Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
Abstract: The inventive subject matter relates to methods for modulating an eicosanoid metabolic process in cells of an animal in need thereof, which comprises administering to the animal an amount of the inventive compositions effective for regulating the activity of an eicosanoid oxygenase. In particular, the inventive subject matter relates to methods for modulating arachadonic acid metabolism by administering an amount of the inventive compositions effective for regulating the activity of lipoxygenases and cyclooxygenases.
Type:
Grant
Filed:
June 14, 2006
Date of Patent:
July 21, 2009
Assignees:
The University of Texas MD Anderson Cancer Center, New Chapter Inc.
Inventors:
Thomas Newmark, Paul Schulick, Robert Newman, Bharat Aggarwal
Abstract: This invention provides compositions and methods for treating neoplasias in a mammal. In particular, the invention provides liposome-encapsulated vinca alkaloids, e.g., vinorelbine, and methods of treating a mammal using such compositions.
Type:
Application
Filed:
April 3, 2003
Publication date:
April 15, 2004
Applicants:
Inex Pharmaceuticals Corporation, The University of Texas, MD Anderson Cancer Center
Inventors:
Andreas H. Sarris, Fernando Cabanillas, Patricia M. Logan, Clive T. R. Burge, James H. Goldie, Murray S. Webb, Thomas D. Madden, Sean C. Semple, Quet F. Ahkong, Sandra K. Klimuk