Patents Assigned to The University of Texas System Cancer Center
  • Quadroma cells and trioma cells and methods for the production of same
    Patent number: 4714681
    Abstract: Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.
    Type: Grant
    Filed: June 18, 1984
    Date of Patent: December 22, 1987
    Assignee: The Board of Reagents, The University of Texas System Cancer Center
    Inventor: Christopher L. Reading
  • Recombinant monoclonal antibodies
    Patent number: 4474893
    Abstract: Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.
    Type: Grant
    Filed: July 1, 1981
    Date of Patent: October 2, 1984
    Assignee: The University of Texas System Cancer Center
    Inventor: Christopher L. Reading