Patents Assigned to The University of Toledo
  • Control system for bearingless motor-generator
    Patent number: 7667418
    Abstract: A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
    Type: Grant
    Filed: October 30, 2008
    Date of Patent: February 23, 2010
    Assignee: The University of Toledo
    Inventors: Peter E. Kascak, Ralph H. Jansen, Timothy P. Dever
  • Control system for bearingless motor-generator
    Patent number: 7456537
    Abstract: A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: November 25, 2008
    Assignee: The University of Toledo
    Inventors: Peter E. Kascak, Ralph H. Jansen, Timothy P. Dever
  • Circuit with a switch for charging a battery in a battery capacitor circuit
    Patent number: 7417407
    Abstract: A circuit for charging a battery combined with a capacitor includes a power supply adapted to be connected to the capacitor, and the battery. The circuit includes an electronic switch connected to the power supply. The electronic switch is responsive to switch between a conducting state to allow current and a non-conducting state to prevent current flow. The circuit includes a control device connected to the switch and is operable to generate a control signal to continuously switch the electronic switch between the conducting and non-conducting states to charge the battery.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: August 26, 2008
    Assignee: The University of Toledo
    Inventors: Thomas A. Stuart, Cyrus N. Ashtiani
  • Noninvasive birefringence compensated sensing polarimeter
    Patent number: 7245952
    Abstract: The present invention relates to a system and method for compensating for the effects of birefringence in a given sample and employs an optical birefringence analyzer to sense the real-time birefringence contributions and then provides a feedback signal to a compound electro-optical system that negates the birefringence contributions found in the given sample. The birefringence contribution vanishes, thus significantly reducing the main error component for polarimetric measurements.
    Type: Grant
    Filed: January 12, 2005
    Date of Patent: July 17, 2007
    Assignee: The University of Toledo
    Inventor: Brent D. Cameron
  • Aralkyl ester soft drugs
    Patent number: 7164027
    Abstract: The present invention describes a method for programming a specific course and rate of metabolism for a parent drug compound that leads to an inactive or very weakly active and nontoxic metabolite when the modified drug compound is administered.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: January 16, 2007
    Assignee: The University of Toledo
    Inventor: Paul W. Erhardt
  • Cyclic beta-sheet peptides useful as apoptotic/cytotoxic cancer agents
    Patent number: 7105635
    Abstract: Peptides and pharmaceutical compositions of matter useful as cytotoxic compositions particularly for, but not limited to, treatment of cancers, that includes a synthetic peptide whose amino acid sequence is different from an initial loop of cobra cardiotoxin.
    Type: Grant
    Filed: June 4, 2002
    Date of Patent: September 12, 2006
    Assignee: The University of Toledo
    Inventors: Channing L. Hinman, Charles A. Smith
  • Method and compositions for temporarily incapacitating subjects
    Patent number: 7049326
    Abstract: A method for modifying at least one non-ester-containing parent compound, and the compounds produced using such method, which compounds are deployed to temporarily incapacitate at least one subject are disclosed. The modified compounds are rapidly metabolized to inactive and non-toxic metabolites when exposure to the modified compounds is halted.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: May 23, 2006
    Assignee: The University of Toledo
    Inventor: Paul W. Erhardt
  • Bioartificial intervertebral disc
    Patent number: 6958078
    Abstract: A bioartificial nucleus pulposus is adapted for replacing at least a portion of a natural nucleus pulposus in an intervertebral disc. The bioartificial nucleus pulposus includes an artificial support structure made from a biodegradable material. The support structure has a plurality of pores. A carrier material is contained in the pores of the support structure. A plurality of nucleus pulposus cells are carried by the carrier material. A bioartificial intervertebral disc contains the bioartificial nucleus pulposus.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: October 25, 2005
    Assignee: The University of Toledo
    Inventors: Vijay K. Goel, Ronald L. Fournier
  • Method for the selective removal of acyl-functionality attached to the 2'-hydroxy-group of paclitaxel-related derivatives
    Patent number: 6846937
    Abstract: A method for removing acyl-groups appended by an ester linkage to the 2?-hydroxyl group present in paclitaxel-related molecules comprising treatment with alcohol under non-acidic conditions.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: January 25, 2005
    Assignee: The University of Toledo
    Inventors: Paul W. Erhardt, Wieslaw A. Klis, Jeffery G. Sarver
  • Hot-filament chemical vapor deposition chamber and process with multiple gas inlets
    Patent number: 6755151
    Abstract: A thin film deposition method uses a vacuum confinement cup that employs a dense hot filament and multiple gas inlets. At least one reactant gas is introduced into the confinement cup both near and spaced apart from the heated filament. An electrode inside the confinement cup is used to generate plasma for film deposition. The method is used to deposit advanced thin films (such as silicon based thin films) at a high quality and at a high deposition rate.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: June 29, 2004
    Assignee: The University of Toledo
    Inventors: Xunming Deng, Henry S. Povolny
  • Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
    Patent number: 6756047
    Abstract: A method and compositions for treating persistent pulmonary hypertension in human newborns that deploys an intravenous infusion of a modified drug formed by adding one or more of a predetermined chemical arrangement to an efficacious parent drug compound so as to retain efficacy while re-directing a preferred route and rate of the parent drug compound's metabolism to an inactive or very weakly active and non-toxic metabolite are disclosed.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: June 29, 2004
    Assignee: The University of Toledo
    Inventors: Paul W. Erhardt, Moustafa M. Aouthmany
  • Aralkyl ester soft drugs
    Patent number: 6750238
    Abstract: The present invention describes a method for programming a specific course and rate of metabolism for a parent drug compound that leads to an inactive or very weakly active and nontoxic metabolite when the modified drug compound is administered.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: June 15, 2004
    Assignee: The University of Toledo
    Inventor: Paul W. Erhardt
  • Method of measuring surface plasmon resonance using interference structure of reflected beam profile
    Patent number: 6731388
    Abstract: Changes in optical properties of layered materials are measured by directing an incident wave of finite transverse dimensions toward layered materials under conditions that will produce a propagating surface mode or a waveguide mode in the layered materials. The intensity distribution is measured within the transverse beam profile of the total reflected beam. The profile shows asymmetric structure associated with the excitation of the propagating surface mode or a wave-guide mode. The index of refraction of the layered materials is modified and the reshaped intensity distribution within the transverse beam profile of the total reflected beam is again measured under the same incidence conditions. The measured intensity distributions are compared to detect differences in the indexes of refraction in the layered materials.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: May 4, 2004
    Assignee: The University of Toledo
    Inventors: Henry J. Simon, Robert T. Deck, Richard V. Andaloro
  • Hot-filament chemical vapor deposition chamber and process with multiple gas inlets
    Patent number: 6638839
    Abstract: A thin film deposition method uses a vacuum confinement cup that employs a dense hot filament and multiple gas inlets. At least one reactant gas is introduced into the confinement cup both near and spaced apart from the heated filament. An electrode inside the confinement cup is used to generate plasma for film deposition. The method is used to deposit advanced thin films (such as silicon based thin films) at a high quality and at a high deposition rate.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: October 28, 2003
    Assignee: The University of Toledo
    Inventors: Xunming Deng, Henry S. Povolny
  • Muscarinic receptor agonists
    Patent number: 6602891
    Abstract: A compound of Formula (III): wherein X is a linkage independently selected from (CH2)12 or (CH2CH2)4O3 and wherein R3 is independently selected from H, CH2CH3, COCH3 or and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: August 5, 2003
    Assignee: The University of Toledo
    Inventors: William S. Messer, Yang Cao
  • Blast load simulation system
    Patent number: 6536258
    Abstract: A blast load simulation system includes a glass panel having two surfaces. The system also includes a membrane for covering at least one of the two surfaces of the glass panel. The system also includes means for delivering an impulse with a given characteristic to the glass panel through the membrane.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: March 25, 2003
    Assignee: The University of Toledo
    Inventor: Naser Mostaghel
  • Novel hot-filament chemical vapor deposition chamber and process with multiple gas inlets
    Publication number: 20030032265
    Abstract: A thin film deposition method uses a vacuum confinement cup that employs a dense hot filament and multiple gas inlets. At least one reactant gas is introduced into the confinement cup both near and spaced apart from the heated filament. An electrode inside the confinement cup is used to generate plasma for film deposition. The method is used to deposit advanced thin films (such as silicon based thin films) at a high quality and at a high deposition rate.
    Type: Application
    Filed: July 25, 2002
    Publication date: February 13, 2003
    Applicant: The University of Toledo
    Inventors: Xunming Deng, Henry S. Povolny
  • Method for measurement of physical characteristics of crystals
    Patent number: 6498829
    Abstract: A method and apparatus to simultaneously measure the diffraction resolution and mosaic spread of macromolecular crystals, are described. The method includes minimizing contributions of an x-ray beam to any reflection angular widths in the crystal, rapidly measuring multi reflection profiles in the crystal over a wide resolution range, evaluating and deconvoluting the Lorentz effect and beam contributions, and determining the direction in which the crystal is most perfect.
    Type: Grant
    Filed: June 28, 2001
    Date of Patent: December 24, 2002
    Assignee: The University of Toledo
    Inventors: Gloria E. O. Borgstahl, Jeffrey J. Lovelace, Edward H. Snell
  • Helices and nanotubes on folding compositions and method of making same
    Patent number: 6495680
    Abstract: Helical oligomer and polymer compositions that form nanotubes are described. The compositions comprise a plurality of aromatic substituents linked by at least one amide group. The compositions have a curved backbone due to intramolecular hydrogen bonds that rigidify the amide linkage of each amide group to each aromatic substituent and due to an interaction between the aromatic substituents such that the curved backbone is stabilized. The helical compositions are formed by ridigifying the amide group, which is flanked on each side by the aromatic substituents, by introducing intramolecular hydrogen bonds into a linkage between the amide group and each aromatic substituent such that the compositions fold into a helical shape when the amide linkages are meta to each other.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: December 17, 2002
    Assignee: The University of Toledo
    Inventor: Bing Gong
  • Muscarinic receptor agonists
    Patent number: 6376675
    Abstract: A compound of Formula (III): wherein X is a linkage independently selected from (CH2)12 or (CH2CH2)4O3 and wherein R3 is independently selected from H, CH2CH3, COCH3 or and acid addition salts, solvates and hydrates thereof. The compounds have unusually high affinity for muscarinic receptors, and exhibit agonist activity useful in the treatment of neurological and other disorders, in which stimulating cholinergic activity is desirable.
    Type: Grant
    Filed: January 29, 2001
    Date of Patent: April 23, 2002
    Assignee: The University of Toledo
    Inventors: William S. Messer, Yang Cao