Abstract: A carbon nanotube composite is a carbon nanotube composite including one carbon nanotube and an amorphous carbon-containing layer that coats the carbon nanotube, the carbon nanotube having a D/G ratio of 0.1 or less, the D/G ratio being a ratio of a peak intensity of a D band to a peak intensity of a G band in Raman spectroscopic analysis with a wavelength of 532 nm, the carbon nanotube composite being fibrous and having a diameter of 0.1 ?m or more and 50 ?m or less.
Type:
Application
Filed:
August 29, 2019
Publication date:
July 15, 2021
Applicants:
SUMITOMO ELECTRIC INDUSTRIES, LTD., UNIVERSITY OF TSUKUBA
Abstract: The present invention provides a therapeutic agent and others for various tumors including angioimmunoblastic T-cell lymphoma (AITL), which is an orphan disease. The present invention relates to a therapeutic agent and others for tumors identified by phosphorylation of a proto-oncogene protein belonging to the VAV family, which comprises dasatinib or a prodrug thereof or a pharmacologically acceptable salt thereof or a hydrate or solvate thereof as an active ingredient.
Abstract: A physiological state evaluation apparatus contacts an external auditory pore when mounted in a subject's auricle. The evaluation apparatus: collects sound vibrations generated from a larynx and a pharynx via a cartilage region of the external auditory pore; optically detects a pulsatory motion of blood through blood vessels and measures pulse rate and blood oxygen saturation, on the basis of a change in optical intensity caused by the pulsatory motion; detects brain waves and eye movements using a pair of conductive electrodes for detecting electric potentials of right and left external auditory pore surfaces; detects, sound quality, number of times, tidal volume, and rhythm of the subject's breaths on the basis of the acoustic signal; and evaluates a health condition of the subject while sleeping on the basis of the respiratory condition, the pulse rate and the blood oxygen saturation, and the brain waves and the eye movements.
Abstract: A photoacoustic imaging apparatus comprises: a light emitting unit emitting pulsed light with a wavelength absorbed inside a subject; a thin, flexible film applied to a skin surface of the subject to make the pulsed light transmit it and reflects the light on its outer surface at the same time; a multi-directional light emitting unit emitting a plurality of visible light beams from multi-directions to the outer surface of the thin film; a micro-vibration detection unit detects, on the basis of diffraction and/or interference of a plurality of reflected light obtained from the outer surface of the thin film, a state of causing micro-vibrations of the thin film as the photoacoustic waves generated from the light absorber collide against an inner backside of the thin film; and a shape image transformation unit that produces the images of a shape of the light absorber as detected by the micro-vibration detection unit.
Abstract: Problem to be Solved A traverse that is percutaneously provided and a surgical instrument for percutaneously providing the transverse are provided. Solution A rod 10 is placed in each of two rod openings 113, 123 and a transverse bar 130 is inserted in two bar holes 111, 121. Set screws 140, 150 are screwed in screw holes 114, 124. The set screws 140, 150 press the transverse bar 130, thereby restraining the transverse bar 130 in the longitudinal direction. Since portions of the bar holes 111, 121 adjoin the rod openings 113, 123, the pressed transverse bar 130 contacts the rods 10 and pushes the rods 10 against the rod openings 113, 123. A protrusion 127 engages with the rods 10 to restrain hooks 110, 120 in the longitudinal direction and circumferential direction of the rods 10.
Abstract: Provided are a mobility and a mobility system which enable a person who requires nursing care with a deteriorated bodily function or cognitive function to lead a life with greater independence. The drive and travel of the mobility by the travel drive unit are controlled by adjusting the current travel state of the mobility to an optimal travel state for ensuring safety while reflecting the user's intention based on the current operation instruction detected by the operation unit, the command signal generated by the voluntary control unit, the travel environment sensed by the environment sensing unit, and the respective types of environmental information acquired by the information acquisition unit.
Abstract: A data creation method includes: an autofluorescence data generation step of placing a focus of light having a predetermined wavelength at one set of coordinates on a predetermined focal plane, irradiating a sample positioned at the set of coordinates with excitation light containing the light to obtain autofluorescence emitted from the sample, and generating autofluorescence data including intensity data and/or spectrum data of the autofluorescence; a reflected light data generation step of irradiating the set of coordinates on the predetermined focal plane with illumination light to obtain reflected light scattered by the sample, and generating intensity data of the reflected light; and a correspondence data creation step of creating correspondence data associating the autofluorescence data and the reflected light data on the set of coordinates on the predetermined focal plane.
Abstract: An expression system is provided, including a first nucleic acid fragment containing a long intergenic region (LIR) derived from geminivirus, a small intergenic region (SIR) derived from geminivirus, and an expression cassette of a target protein linked between the LIR and the SIR and a second nucleic acid fragment containing an expression cassette of a Rep/RepA protein derived from geminivirus, in which the expression cassette of the target protein includes a promoter, a nucleic acid fragment encoding the target protein, and two or more linked terminators in this order.
Type:
Application
Filed:
March 6, 2018
Publication date:
April 15, 2021
Applicant:
University of Tsukuba
Inventors:
Kenji MIURA, Hiroshi EZURA, Ken HOSHIKAWA
Abstract: A fluoride sintered body suitable for a moderator which moderates high-energy neutrons so as to generate neutrons for medical care with which an affected part of the deep part of the body is irradiated to make a tumor extinct comprises MgF2 of a compact polycrystalline structure having a bulk density of 2.90 g/cm3 or more and as regards mechanical strengths, a bending strength of 10 MPa or more and a Vickers hardness of 71 or more.
Type:
Grant
Filed:
May 27, 2014
Date of Patent:
March 30, 2021
Assignees:
UNIVERSITY OF TSUKUBA, DAICO MFG CO., LTD.
Abstract: The present invention aims to provide a novel low-molecular-weight compound showing an orexin receptor agonist activity and expected to be useful as a prophylactic or therapeutic agent for narcolepsy and the like. The present invention provides a compound represented by the formula (I): wherein each symbol is as described in the description, or a pharmaceutically acceptable acid addition salt thereof, which has an orexin receptor agonist activity, and an orexin receptor agonist containing the compound or a pharmaceutically acceptable acid addition salt thereof.
Type:
Application
Filed:
December 11, 2018
Publication date:
March 18, 2021
Applicants:
University of Tsukuba, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Abstract: [Problem] Learning of object operation skills robust against variation of conditions is implemented. [Solution] A behavior estimation apparatus 100 includes a collection unit 200 configured to collect skill data obtained when a slave robot is operated under a plurality of different conditions by using a bilateral system capable of operating the slave robot via a master robot through bidirectional control between the master robot and the slave robot. The behavior estimation apparatus 100 further includes a behavior estimation device 300 configured to estimate a command value for causing the slave robot 520 to automatically behave, based on the skill data collected by the collection unit 200 and a response output from the slave robot 520.
Abstract: Problem to be Solved A traverse that is percutaneously provided and a surgical instrument for percutaneously providing the transverse are provided. Solution A rod 10 is placed in each of two rod openings 113, 123 and a transverse bar 130 is inserted in two bar holes 111, 121. Set screws 140, 150 are screwed in screw holes 114, 124. The set screws 140, 150 press the transverse bar 130, thereby restraining the transverse bar 130 in the longitudinal direction. Since portions of the bar holes 111, 121 adjoin the rod openings 113, 123, the pressed transverse bar 130 contacts the rods 10 and pushes the rods 10 against the rod openings 113, 123. A protrusion 127 engages with the rods 10 to restrain hooks 110, 120 in the longitudinal direction and circumferential direction of the rods 10.
Abstract: A data creation method includes: an autofluorescence data generation step of placing a focus of light having a predetermined wavelength at one set of coordinates on a predetermined focal plane, irradiating a sample positioned at the set of coordinates with excitation light containing the light to obtain autofluorescence emitted from the sample, and generating autofluorescence data including intensity data and/or spectrum data of the autofluorescence; a reflected light data generation step of irradiating the set of coordinates on the predetermined focal plane with illumination light to obtain reflected light scattered by the sample, and generating intensity data of the reflected light; and a correspondence data creation step of creating correspondence data associating the autofluorescence data and the reflected light data on the set of coordinates on the predetermined focal plane.
Abstract: A model of a body part, e.g., liver, of which the internal structure can be observed easily; and others. In a liver model according to the present invention, the liver parenchyma is formed in the form of a frame to make it possible to observe the portal, veins, a tumor and others in the inside of the frame 31a easily. In addition, the liver model can be handled easily by gripping a gripping part provided at the lower end surface of the inferior vena cava, and the tumor is integrated with the liver model by means of a joint part. The liver model can be manufactured from a model material using a 3D printer on the basis of three-dimensional shape data for model manufacturing purposes, which are produced using an information processing device.
Type:
Grant
Filed:
February 22, 2016
Date of Patent:
November 24, 2020
Assignees:
UNIVERSITY OF TSUKUBA, DAI NIPPON PRINTING CO., LTD.
Abstract: Biomarkers for detecting cognitive dysfunction diseases and methods for detecting cognitive dysfunction diseases using the biomarkers are provided. A method for detecting cognitive dysfunction diseases comprising measuring one or more biomarkers for detecting cognitive dysfunction diseases selected from the following (a), (b), and (c) in a biological sample simultaneously or separately: (a) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of apolipoprotein A1 comprising the amino acid sequence represented by SEQ ID NO:1 or a partial peptide thereof; (b) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of transthyretin comprising the amino acid sequence represented by SEQ ID NO:2 or a partial peptide thereof; and (c) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of complement C3 comprising the amino acid sequence represented by SEQ ID NO:3 or a partial peptide thereof.
Abstract: A carbon nanostructure producing method includes a growth step in which a plurality of catalyst particles in close contact with each other are separated in a flow of a carbon-containing gas so as to grow carbon nanotubes between the plurality of catalyst particles, and an elongation step in which the carbon nanotube is elongated by a wind pressure of the carbon-containing gas with at least one of the catalyst particles being retained.
Type:
Application
Filed:
June 29, 2018
Publication date:
September 17, 2020
Applicants:
SUMITOMO ELECTRIC INDUSTRIES, LTD., UNIVERSITY OF TSUKUBA
Abstract: A MgF2 system fluoride sintered body for a radiation moderator having a compact polycrystalline structure excellent in radiation moderation performance, especially neutron moderation performance, contains CaF2 of 90% by weight at the maximum and has a relative density of 95.2% or more.
Type:
Grant
Filed:
December 18, 2015
Date of Patent:
September 15, 2020
Assignees:
TECHNO EYE CORPORATION, DAICO MFG CO., LTD., UNIVERSITY OF TSUKUBA
Abstract: The present invention relates to a plant having an improved sugar content in fruit compared with its wild type plant, which has a mutant cyclin F-box gene comprising a nucleotide mutation that causes a non-conservative amino acid substitution in the cyclin F-box protein. The present invention also relates to a parthenocarpic plant having a mutant cyclin F-box gene comprising a nucleotide mutation that causes a non-conservative amino acid substitution in the cyclin F-box protein.