Patents Assigned to The University of VA Patent Foundation
  • Production of adenoviral vectors using serum-free suspension cell culture in a hollow fiber system
    Patent number: 6342384
    Abstract: The present invention relates to methods for the production of high titers of serum-free lytic viruses in a hollow fiber cartridge capillary system. The invention further relates to methods of infecting target cells at high multiplicity and for producing high concentrations of transduced target cells.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: January 29, 2002
    Assignee: The University of VA Patent Foundation
    Inventors: Leland W. K. Chung, Thomas A. Gardner, Chinghai Kao, Song-Chu Ko