Patents Assigned to The University of York
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Patent number: 12209241Abstract: The disclosure relates to the assembly of Virus Like Particles [VLPs] using packaging native and artificial packaging signals and their use in vaccines and immunological compositions and the methods of vaccination or immunisation against human and animal viral pathogens.Type: GrantFiled: May 31, 2018Date of Patent: January 28, 2025Assignees: The University of Leeds, The University of YorkInventors: German Leonov, Simon White, Peter Stockley, Nikesh Patel, Emma Wroblewski, Dan Maskell, Reidun Twarock, Richard Bingham, Eva Weiss, Eric Dykeman
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Publication number: 20240358043Abstract: The present disclosure relates to a method for cultivation of insect biomass, for example, larvae and/or eggs using a feed comprising lignocellulose incubated with lignocellulose digesting fungal cells; a feed comprising pre-treated lignocellulose for cultivation of insect biomass; and a livestock feed obtained through the cultivation method of insect biomass.Type: ApplicationFiled: April 21, 2022Publication date: October 31, 2024Applicant: The University of YorkInventors: Neil Bruce, Alexander Setchfield, Daniel Leadbeater
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Patent number: 11897917Abstract: Certain embodiments of the present invention relate to methods of forming and manipulating bioconjugates. Particularly, but not exclusively certain embodiments relate to methods of reversible carbon-carbon bond bioconjugation using aldol based chemical reactions at physiological conditions.Type: GrantFiled: September 27, 2017Date of Patent: February 13, 2024Assignee: The University of YorkInventors: Martin A. Fascione, Richard J. Spears, Robin Brabham, Darshita Budhadev, Tessa Keenan
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Publication number: 20230203461Abstract: The present application relates to nucleic acids encoding polypeptides with ?-etherase activity; polypeptides with ?-etherase activity; vectors comprising said nucleic acids for the production of recombinant ?-etherase; cells, for example microbial cells transformed with nucleic acids encoding ?-etherase activity and vectors, including nucleic acids encoding ?-etherases; a composition comprising ?-etherases suitable for processing lignocellulose and a method that uses ?-etherases or compositions comprising ?-etherases in the processing of lignocellulose and related polysaccharides.Type: ApplicationFiled: January 9, 2021Publication date: June 29, 2023Applicants: The University of York, Wisconsin Alumni Research FoundationInventors: Neil Bruce, Nicola Oates, John Ralph
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Patent number: 11598718Abstract: A method of analysing an aqueous fluid comprising obtaining a 2D-IR spectrum of a sample of the aqueous fluid using a 2D-IR spectrometer configured to apply a sequence of IR pulses to the sample, wherein the sequence comprises a pump process followed by a probe pulse, where the pump process is a single pump pulse or a sequence of a first pump pulse and a second pump pulse, and a waiting time Tw between applying the single pump pulse or the second pump pulse and applying the probe pulse is from 150 to 350 fs.Type: GrantFiled: June 7, 2019Date of Patent: March 7, 2023Assignee: The University of YorkInventors: Matthew Baker, Neil T. Hunt, Samantha Rutherford, Gordon Hithell
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Patent number: 11268101Abstract: The disclosure relates to recombinant protein expression systems comprising genetically modified cells wherein the cells are transformed or transfected with tRNA genes to reduce base mismatch due to genetic degeneracy in the genetic code.Type: GrantFiled: January 9, 2017Date of Patent: March 8, 2022Assignee: The University of YorkInventor: Robert White
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Publication number: 20200165613Abstract: The disclosure relates to the assembly of Virus Like Particles [VLPs] using packaging native and artificial packaging signals and their use in vaccines and immunological compositions and the methods of vaccination or immunisation against human and animal viral pathogens.Type: ApplicationFiled: May 31, 2018Publication date: May 28, 2020Applicants: The University of Leeds, The University of YorkInventors: German Leonov, Simon White, Peter Stockley, Nikesh Patel, Emma Wroblewski, Dan Maskell, Reidun Twarock, Richard Bingham, Eva Weiss, Eric Dykeman
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Patent number: 10400222Abstract: The disclosure relates to delta (12) and delta (15) desaturases and their use in the modification of oil content in hemp.Type: GrantFiled: December 8, 2014Date of Patent: September 3, 2019Assignee: The University of YorkInventors: Monika Bielecka, Filip Kaminski, Thilo Winzer, Ian Graham
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Publication number: 20190218529Abstract: The present disclosure relates to nucleic acids that encode polypeptides with cytochrome P450 activity involved in the biosynthesis of plant derived diterpenoids or diterpenes.Type: ApplicationFiled: March 28, 2019Publication date: July 18, 2019Applicant: The University of YorkInventors: Andrew King, Ian Graham
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Publication number: 20190106684Abstract: The present disclosure relates to nucleic acids that encode enzyme activities involved in the synthesis of lathyranes, intermediates in the synthesis of lathyranes and also compounds derived from lathyranes such as tiglianes, daphnanes and ingenanes; cells transformed with the nucleic acid molecules and vectors comprising the nucleic acid molecules.Type: ApplicationFiled: March 13, 2017Publication date: April 11, 2019Applicant: The University of YorkInventors: Ian Graham, Andrew King
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Patent number: 10246688Abstract: The present disclosure relates to nucleic acids that encode polypeptides with cytochrome P450 activity involved in the biosynthesis of plant derived diterpenoids or diterpenes.Type: GrantFiled: January 9, 2015Date of Patent: April 2, 2019Assignee: The University of YorkInventors: Andrew King, Ian Graham
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Publication number: 20180362992Abstract: The disclosure relates to recombinant protein expression systems comprising genetically modified cells wherein the cells are transformed or transfected with tRNA genes to reduce base mismatch due to genetic degeneracy in the genetic code.Type: ApplicationFiled: January 9, 2017Publication date: December 20, 2018Applicant: The University of YorkInventor: Robert White
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Patent number: 10006010Abstract: This disclosure relates to the isolation of a nucleic acid molecule[s] that encode a novel cytochrome P450 and an oxidoreductase from a Papaver somniferum [P. somniferum] cultivar, transgenic cells transformed with said nucleic acid molecule and sequence variants thereof; and including methods for the production of intermediates in the production of morphinans.Type: GrantFiled: May 15, 2015Date of Patent: June 26, 2018Assignees: The University of York, Sun Pharmaceutical Industries (Australia) Pty LtdInventors: Thilo Winzer, Ian Graham, Tracy Carol Walker
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Publication number: 20180158962Abstract: A pulse generation device includes a substrate, a spin injector provided on the substrate and made of a ferromagnetic body, a spin rotor provided on the substrate, made of a ferromagnetic body, and having magnetic anisotropy in which a direction of a first axis becomes an easy axis of magnetization, a channel portion made of a nonmagnetic body, and joined with the spin injector and the spin rotor directly or via an insulating layer, and a generating portion configured to generate a pulse by detecting, when a magnetic moment of the spin rotor is reversed from a state in which the magnetic moment faces one side of the first axis to a state in which the magnetic moment faces the other side of the first axis, a state in which the magnetic moment of the spin rotor faces a direction along a second axis orthogonal to the first axis.Type: ApplicationFiled: May 20, 2016Publication date: June 7, 2018Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, THE UNIVERSITY OF YORKInventor: Atsufumi HIROHATA
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Patent number: 9882118Abstract: A spin control mechanism includes a spin portion and a first channel portion. The spin portion has a magnetic moment that can be reversed and rotated. The first channel portion is provided in contact with the spin portion, and is configured from ferromagnetic insulator. Then, the spin control mechanism controls a direction of the magnetic moment of the spin portion using a spin current generated by a temperature gradient provided to the first channel portion.Type: GrantFiled: October 29, 2014Date of Patent: January 30, 2018Assignees: JAPAN SCIENCE AND TECHNOLOGY AGENCY, THE UNIVERSITY OF YORKInventor: Atsufumi Hirohata
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Publication number: 20170058267Abstract: This disclosure relates to the isolation of a nucleic acid molecule[s] that encode a novel cytochrome P450 and an oxidoreductase from a Papaver somniferum [P. somniferum] cultivar, transgenic cells transformed with said nucleic acid molecule and sequence variants thereof; and including methods for the production of intermediates in the production of morphinans.Type: ApplicationFiled: May 15, 2015Publication date: March 2, 2017Applicants: The University of York, Sun Pharmaceutical Industries (Australia) Pty LtdInventors: Thilo Winzer, Ian Graham, Tracy Carol Walker
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Patent number: 9553256Abstract: A spin valve element 10 including a spin injector 12 made of a ferromagnetic material, a spin detector 16 made of a ferromagnetic material, and a channel part 14 made of a non-magnetic material. The spin detector 16 is arranged at a position separated from the spin injector 12, the channel part 14 is connected with the spin injector 12 and the spin detector 16 directly or through an insulating layer, and a plurality of spin diffusion portions 30 to 34 with enlarged cross section areas in a direction perpendicular to a spin current is formed in the channel part 14.Type: GrantFiled: October 31, 2013Date of Patent: January 24, 2017Assignees: Japan Science and Technology Agency, The University of YorkInventor: Atsufumi Hirohata
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Patent number: 9548634Abstract: A spin rotary member includes a substrate, a spin injector made of a ferromagnetic material magnetized in a substrate in-plane direction, and provided on the substrate, a spin rotor made of a ferromagnetic material having a magnetic moment rotatable in the substrate in-plane direction, and provided on the substrate, being separated from the spin injector, a channel part made of a non-magnetic material, arranged between the spin injector and the spin rotor, and bonded with the spin injector and the spin rotor directly or through an insulating layer, and a spin rotation control part configured to control a rotation direction of spin of the channel part.Type: GrantFiled: July 25, 2013Date of Patent: January 17, 2017Assignees: Japan Science and Technology Agency, The University of YorkInventor: Atsufumi Hirohata
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Publication number: 20160359104Abstract: A crystallisation method for an alloy film such as a Co-based ternary Heusler-alloy is described having the steps of: providing a substrate; depositing a layer of the alloy film to be crystallised onto the substrate using a physical vapour deposition process to a depth of up to a few hundred nm; optionally depositing a capping layer thereon; heating the deposited film at an annealing temperature below 300° C. and for example of around 200° C. to 300° C. to effect crystallisation of the alloy film layer. The method is in particular applied to the in the deposition and annealing in situ of an alloy film in or on a semiconductor device for example as a functional film in or on such a device and in particular to the deposition and annealing in situ of a highly-spin-polarised ferromagnetic thin film on a semiconductor or spintronic device.Type: ApplicationFiled: February 12, 2015Publication date: December 8, 2016Applicant: The University of YorkInventors: Luke Roger Fleet, Atsufumi Hirohata, James Thomas Sagar
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Publication number: 20160333324Abstract: The disclosure relates to delta (12) and delta (15) desaturases and their use in the modification of oil content in hemp.Type: ApplicationFiled: December 8, 2014Publication date: November 17, 2016Applicant: The University of YorkInventors: Monika Bielecka, Filip Kaminski, Thilo Winzer, Ian Graham