Patents Assigned to THE UNIVERSITY TOKYO
  • Patent number: 10261090
    Abstract: [Problem] To provide the following: a novel fluorescent probe for detecting a compound, such as glutathione, that contains a —SH group; a detection method using said fluorescent probe; and a detection kit containing said probe.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: April 16, 2019
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Yasuteru Urano, Mako Kamiya, Keitaro Umezawa, Masafumi Yoshida
  • Patent number: 10260173
    Abstract: The problem of the present invention is to provide a carbon fiber manufacturing device in which fiber to be carbonized is irradiated with microwaves and thereby heated, wherein the carbon fiber manufacturing device is compact and capable of performing carbonization at atmospheric pressure without requiring an electromagnetic wave absorber or other additives or preliminary carbonization through external heating. This carbon fiber manufacturing device (200) includes: a cylindrical furnace (27) comprising a cylindrical waveguide in which one end is closed, a fiber outlet (27b) being formed in the one end of the cylindrical waveguide and a fiber inlet (27a) being formed in the other end of the cylindrical waveguide; a microwave oscillator (21) for introducing microwaves into the cylindrical furnace (27); and a connection waveguide (22) having one end connected to the microwave oscillator (21) side and the other end connected to one end of the cylindrical furnace (27).
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: April 16, 2019
    Assignees: TEIJIN LIMITED, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO
    Inventors: Hiroaki Zushi, Takaya Suzuki, Jun-ichi Sugiyama
  • Patent number: 10262762
    Abstract: In a vascular data generation apparatus, a processor generates first vascular data based on anatomical statistics data about vessels of an organ. This first vascular data has a tree structure representing a vascular network in the organ. The processor further generates second vascular data representing a plurality of vessels that connect a plurality of nodes in a geometric model of the organ with the vascular network represented by the first vascular data.
    Type: Grant
    Filed: July 31, 2014
    Date of Patent: April 16, 2019
    Assignees: FUJITSU LIMITED, THE UNIVERSITY OF TOKYO
    Inventors: Takashi Iwamura, Toshiaki Hisada, Seiryo Sugiura, Takumi Washio, Jun-ichi Okada
  • Publication number: 20190106103
    Abstract: A driving assistance control device includes an active pedal configured to control a driving and braking force of a vehicle, an electronic control unit configured to detect a potential risk area in which an obstacle entering a scheduled traveling route of the vehicle is likely to be present, and determine a reference speed at which contact between the vehicle and the obstacle can be avoided even when the obstacle enters the scheduled traveling route of the vehicle from the detected potential risk area based on a positional relationship between the vehicle and the potential risk area, and a force feedback unit configured to apply an assistance reaction force in a direction in which the amount of manipulation is reduced, to the active pedal when a current speed of the vehicle exceeds the reference speed.
    Type: Application
    Filed: September 25, 2018
    Publication date: April 11, 2019
    Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, National University Corporation Tokyo University of Agriculture and Technology, THE UNIVERSITY OF TOKYO, SCHOOL JUDICIAL PERSON IKUTOKU GAKUEN
    Inventors: Shintaro INOUE, Pongsathorn RAKSINCHAROENSAK, Yuichi SAITO, Takuma ITO, Tsukasa SHIMIZU, Hideo INOUE
  • Publication number: 20190106104
    Abstract: A drive assist apparatus includes an electronic control unit configured to: compute, when an object that causes a blind spot is ahead of a host vehicle, a first reference velocity which is a velocity at which the host vehicle is able to run without colliding with a moving object assumed to be in the blind spot of the object; estimate a degree of risk associated with a road on which the host vehicle is running, based on environment information that indicates a running environment of the host vehicle; and compute a second reference velocity which is determined by correcting the first reference velocity based on the estimated degree of risk.
    Type: Application
    Filed: September 26, 2018
    Publication date: April 11, 2019
    Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY O F AGRICULTURE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO, SCHOOL JUDICIAL PERSON IKUTOKU GAKUEN
    Inventors: Shintaro INOUE, Toshiki KINOSHITA, Pongsathorn RAKSINCHAROENSAK, Yuichi SAITO, Takuma ITO, Tsukasa SHIMIZU, Hideo INOUE
  • Patent number: 10256164
    Abstract: The present invention provides a semiconductor film, a field effect transistor, and a method of fabricating the semiconductor film that has one or two or more semiconductor portions, which are formed from a semiconductor material, and one or two or more polymer portions, which are formed from a polymer material. The semiconductor portion and the polymer portion are adjacent to each other and are integrated.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: April 9, 2019
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Junichi Takeya, Junshi Soeda
  • Publication number: 20190100802
    Abstract: A marker for predicting pressure ulcer development, selected from the group consisting of interleukin (IL)-1?, vascular endothelial growth factor (VEGF)-C, plasminogen activator inhibitor (PAI)-1, and heat-shock protein (HSP) 90?.
    Type: Application
    Filed: January 13, 2017
    Publication date: April 4, 2019
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Hiromi SANADA, Gojiro NAKAGAMI, Takeo MINEMATSU
  • Publication number: 20190100621
    Abstract: The present invention relates to a high molecular weight polymer having an aldaric acid as a constitutional unit, and a method for producing the same, and more specifically, relates to a thermoplastic polymer which comprises at least one repeating unit derived from an aldaric acid, and has a weight average molecular weight of 3,800 or more.
    Type: Application
    Filed: March 29, 2017
    Publication date: April 4, 2019
    Applicants: THE UNIVERSITY OF TOKYO, ENSUIKO SUGAR REFINING CO., LTD.
    Inventors: Tadahisa IWATA, Yukiko ROGERS, Yuxin WU, Hisaharu MASAKI, Tetsuya ITO, Koji HARA
  • Publication number: 20190100518
    Abstract: The present invention relates to a cross-linking agent for cross-linking an indole-structure-containing molecule to a desired molecule, the cross-linking agent containing, as an effective component, a radical compound having an N-oxy radical group and a group capable of bonding to the desired molecule.
    Type: Application
    Filed: March 8, 2017
    Publication date: April 4, 2019
    Applicant: The University of Tokyo
    Inventors: Motomu KANAI, Kounosuke OISAKI, Yohei SEKI, Daisuke SASAKI, Takashi ISHIYAMA
  • Publication number: 20190101483
    Abstract: Disclosed is a method for assisting prediction of onset of cerebral infarction, based on the number of red blood cells contained in a blood sample collected from a subject, comprising the steps of: calculating an exponent value for the prediction from a first measured value indicating red blood cell count measured by electrical resistance measurement method and a second measured value indicating red blood cell count measured by optical measurement method, comparing the exponent value with a reference range, and suggesting that the subject develops cerebral infarction when the exponent value is outside the reference range.
    Type: Application
    Filed: September 28, 2018
    Publication date: April 4, 2019
    Applicants: KAWASAKI GAKUEN Educational Foundation, THE UNIVERSITY OF TOKYO, SYSMEX CORPORATION
    Inventors: Hiromi KATAOKA, Yutaka YATOMI, Akiko MASUDA, Hironori SHIMOSAKA, Hajimu KAWAKAMI
  • Patent number: 10246679
    Abstract: The present invention provides a method for putting a primed pluripotent stem cell in a less differentiated state, a method for producing a pluripotent stem cell having an improved chimera forming ability from a primed pluripotent stem cell, and a method for producing a chimeric animal by using the pluripotent stem cell obtained by any of these methods. The present invention also provides a composition containing a Wnt/? catenin signal inhibitor.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: April 2, 2019
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Hiromitsu Nakauchi, Hideki Masaki, Hideyuki Murayama
  • Publication number: 20190094248
    Abstract: A fluorescent probe for calcium ion detection that has an excellent photofading resistance and quick Ca2+ detection kinetics and can be localized at an arbitrary site in a cell is provided. The fluorescent probe contains a compound represented by the following general formula (I) or a salt thereof: A method for detecting intracellular calcium ions including (a) introducing the compound above or a salt thereof into a cell and (b) measuring the fluorescence emitted by the compound or a salt thereof in the cell is also provided.
    Type: Application
    Filed: January 13, 2017
    Publication date: March 28, 2019
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Kenzo HIROSE, Daisuke ASANUMA, Kohei MATSUI, Rieko TANAKA
  • Patent number: 10239884
    Abstract: There is provided a series of coelenterazine (CTZ) derivatives as a substrate with high luminescence intensity, which is optimal for maximum luminescence wavelengths at both 400 nm (blue-shifted RLuc luminescence system) and 500 nm (ALuc luminescence system) for bioassays which is more sensitive than known techniques. The novel CTZ derivatives are compounds in which a specific position(s) of the CTZ is/are substituted with a specific substituent(s) as shown, for example, by the Formula [I], and has a higher luminescence intensity than known CTZ derivatives in blue-shifted RLuc luminescence system or ALuc luminescence system.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: March 26, 2019
    Assignees: KEIO UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO
    Inventors: Koji Suzuki, Daniel Citterio, Ryo Nishihara, Sung-Bae Kim, Moritoshi Sato, Takahiro Nakajima
  • Patent number: 10242053
    Abstract: There is a storage apparatus which provides a storage area, comprises a cache memory, reads data into the cache memory from the storage area according to a read request and sends the data from the cache memory, and a computer is coupled to the storage apparatus. The computer receives a data processing request, determines an access usage based on the data processing request (or, the information relating to an access usage of the data processing request), selects a logical device corresponding to the determined access usage from a plurality of logical devices which are allocated to the storage area and issues a read request to the selected logical device.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: March 26, 2019
    Assignees: Hitachi, Ltd., The University of Tokyo
    Inventors: Hideomi Idei, Norifumi Nishikawa, Shinji Fujiwara, Kazuhiko Mogi, Kazuo Goda, Masaru Kitsuregawa
  • Patent number: 10238694
    Abstract: Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: March 26, 2019
    Assignees: The University of Tokyo, School Corporation, Azabu Veterinary Medicine Educational Institution
    Inventors: Kenya Honda, Koji Atarashi, Takeshi Tanoue, Masahira Hattori, Hidetoshi Morita
  • Patent number: 10236083
    Abstract: A visualization apparatus includes a memory unit and a computing unit. The memory unit stores a circulation model in which a vascular network, of an organ, having a diameter equal to or smaller than a predetermined value is defined on a two-dimensional plane, and a simulation result of a blood flow in the vascular network of the circulation model. The computing unit transforms the circulation model into a three-dimensional structure including the vascular network located on a cylindrical surface of a cylinder, and displays the simulation result on the three-dimensional structure.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: March 19, 2019
    Assignees: FUJITSU LIMITED, THE UNIVERSITY OF TOKYO
    Inventors: Masahiro Watanabe, Yoshimasa Kadooka, Toshiaki Hisada, Seiryo Sugiura, Takumi Washio, Jun-Ichi Okada
  • Patent number: 10232187
    Abstract: A coil device for transcranial magnetic stimulation treatment, that generates an overcurrent uniformly across a wide range inside the head of a patient. The coil device includes a winding frame and a coil. A cylindrical surface of the winding frame has: an inner surface section arranged near the cranial surface during use; and an outer surface section forming a convex curved surface protruding towards the outside of the cylindrical surface, relative to a first direction parallel to a neutral axis and a second direction orthogonal to the first direction. The neutral axis draws a convex curve.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: March 19, 2019
    Assignees: OSAKA UNIVERSITY, THE UNIVERSITY OF TOKYO
    Inventors: Youichi Saitoh, Masaki Sekino, Momoko Suyama, Keita Yamamoto
  • Patent number: 10234460
    Abstract: An object of the present invention is to provide a peptide excellent in resistance against metabolism, having a stable structure in vivo, and capable of penetrating a cell membrane and reaching in cells. The present invention provides a macrocyclic peptide having a macrocyclic structure comprised of four or more amino acids. At least two amino acids not adjacent to each other have a hydrophobic side chain and the hydrophobic side chains interact with each other inside the ring of the macrocyclic peptide in a hydrophilic environment.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: March 19, 2019
    Assignee: The University of Tokyo
    Inventor: Hiroaki Suga
  • Patent number: 10234429
    Abstract: According to embodiments, a sensor includes a structure body, a container, a liquid and a sensing unit. The structure body includes a supporter, and a film unit. The film unit includes a first region. The first region includes a first end portion supported by the supporter, and a first portion being displaceable. The film unit includes an opening. The container is connected to the structure body. A first space is defined between the film unit and the container. The liquid is provided inside the first space. The sensing unit senses a displacement of the first portion accompanying a displacement of the liquid.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: March 19, 2019
    Assignees: Kabushiki Kaisha Toshiba, The University of Tokyo
    Inventors: Isao Shimoyama, Kiyoshi Matsumoto, Binh Khiem Nguyen, Hidetoshi Takahashi, Minh Dung Nguyen, Hiroto Tamura, Quang Khang Pham, Takahiro Omori, Osamu Nishimura, Akihiro Kasahara
  • Publication number: 20190074452
    Abstract: Provided are a coating solution for a non-light-emitting organic semiconductor device having high carrier mobility that contains a compound represented by Formula (2) and a solvent having a boiling point of equal to or higher than 100° C., an organic transistor, a compound, an organic semiconductor material for a non-light-emitting organic semiconductor device, a material for an organic transistor, a method for manufacturing an organic transistor, and a method for manufacturing an organic semiconductor film. (In Formula (2), R11 and R12 each independently represent a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, or an alkoxy group and may have a substituent, and an aromatic portion in Formula (2) may be substituted with a halogen atom.
    Type: Application
    Filed: November 5, 2018
    Publication date: March 7, 2019
    Applicants: FUJIFILM Corporation, The University of Tokyo
    Inventors: Hiroaki TSUYAMA, Kimiatsu NOMURA, Yoshihisa USAMI, Masatoshi YUMOTO, Tetsu KITAMURA, Masashi KOYANAGI, Tetsuya WATANABE, Toshihiro OKAMOTO, Junichi TAKEYA