Patents Assigned to The USA, as Repesented by the Secretary, Department of Health and Human Services
  • Methods for treating and preventing infectious disease
    Publication number: 20050101554
    Abstract: Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.
    Type: Application
    Filed: July 25, 2003
    Publication date: May 12, 2005
    Applicants: University of Iowa Research Foundation, The USA, as Repesented by the Secretary, Department of Health and Human Services, Coley Pharmaceutical Group, Inc.
    Inventors: Arthur Krieg, Dennis Klinman, Alfred Steinberg