Abstract: The present invention provides methods and materials for diagnosing cancer in an individual using a tissue, blood or urine sample from the patient. Specifically, the disclosed method comprises determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. The present invention also provides a method for determining the prognosis of a cancer patient by determining the level of one or more metabolite selected from the group consisting of creatine riboside, metabolite 561+, Cortisol sulfate and N-acetylneuraminic acid. Also provided are kits for detecting cancer or determining the prognosis of a cancer patient.
Type:
Grant
Filed:
July 11, 2014
Date of Patent:
August 27, 2019
Assignee:
The USA, as represented by the Secretary, Department of Heath and Human Services
Inventors:
Majda Haznadar, Ewy Mathe, Andrew D. Patterson, Curtis Craig Harris, Frank Gonzalez, Kristopher Krausz, Soumen Manna