Patents Assigned to The Winstar Institute of Anatomy and Biology
  • Rotavirus reassortant vaccine
    Patent number: 6113910
    Abstract: The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: September 5, 2000
    Assignees: The Children's Hospital of Philadelphia, The Winstar Institute of Anatomy and Biology
    Inventors: H Fred Clark, Paul Offit, Stanley A. Plotkin