Patents Assigned to THERABIOPHARMA INC.
  • Drug composition for parenteral administration
    Patent number: 11986530
    Abstract: Provided is a curcumin pharmaceutical preparation that is highly water soluble, can maintain the concentration of free curcumin in the blood sufficiently high by being administered parenterally, can effectively obtain a pharmacological action of curcumin, and is highly safe. A pharmaceutical composition for parenteral administration, including a water-soluble substance conjugate of curcumin as an active component.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: May 21, 2024
    Assignees: THERABIOPHARMA INC., KYOTO UNIVERSITY
    Inventors: Hideaki Kakeya, Masashi Kanai, Nobuaki Takahashi, Tadashi Hashimoto, Atsushi Imaizumi, Hitomi Ozawa
  • NEUTROPHIL-TO-LYMPHOCYTE RATIO DECREASING AGENT
    Publication number: 20240000723
    Abstract: Provided is an agent or a food composition capable of decreasing a neutrophil-to-lymphocyte ratio. An agent for decreasing a neutrophil-to-lymphocyte ratio in blood contains a curcumin as an active ingredient.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 4, 2024
    Applicants: THERABIOPHARMA INC., NATIONAL HOSPITAL ORGANIZATION
    Inventors: Koji HASEGAWA, Tadashi HASHIMOTO, Atsushi IMAIZUMI, Tatsuya OGAWA, Hitomi UMETA, Atsuhiro KISHIMOTO
  • SALT OF CURCUMIN MONOGLUCURONIDE
    Publication number: 20230265118
    Abstract: Provided are a derivative of curcumin monoglucuronide excellent in solubility and chemical stability, which can be provided as pharmaceuticals, and a method for producing the same. A salt of curcumin monoglucuronide represented by Chemical Formula 1, wherein M represents a pharmaceutically acceptable cation, a hydrate thereof, or a solvate thereof.
    Type: Application
    Filed: July 2, 2021
    Publication date: August 24, 2023
    Applicant: THERABIOPHARMA INC.
    Inventors: Atsushi IMAIZUMI, Hitomi UMETA, Yasumichi FUKUDA
  • COMPOSITION CONTAINING CURCUMIN COMPOUND, AND METHOD FOR PRODUCING SAME
    Publication number: 20230084246
    Abstract: Provided are a novel amorphous curcumin compound powdery composition that is inexpensive, is improved in bioabsorbability and bioavailability of curcumin, and has long-term stability, and a method for producing the powdery composition. The present invention relates to a powdery composition containing an amorphous curcumin compound and a hydrophilic modified starch and having a Raman spectrum including one or more peaks at wavenumbers of 1630, 1599, 1428, and 1243 (expressed in ±2 cm?1) and a method for producing the powdery composition.
    Type: Application
    Filed: January 25, 2021
    Publication date: March 16, 2023
    Applicant: THERABIOPHARMA INC.
    Inventors: Masashi ITOH, Satoshi NISHIMURA, Tatsuya OGAWA, Tadashi HASHIMOTO
  • DRUG COMPOSITION FOR PARENTERAL ADMINISTRATION
    Publication number: 20200254105
    Abstract: Provided is a curcumin pharmaceutical preparation that is highly water soluble, can maintain the concentration of free curcumin in the blood sufficiently high by being administered parenterally, can effectively obtain a pharmacological action of curcumin, and is highly safe. A pharmaceutical composition for parenteral administration, including a water-soluble substance conjugate of curcumin as an active component.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Applicants: THERABIOPHARMA INC., KYOTO UNIVERSITY
    Inventors: Hideaki KAKEYA, Masashi Kanai, Nobuaki Takahashi, Tadashi Hashimoto, Atsushi Imaizumi, Hitomi Ozawa
  • DRUG COMPOSITION FOR PARENTERAL ADMINISTRATION
    Publication number: 20190224325
    Abstract: Provided is a curcumin pharmaceutical preparation that is highly water soluble, can maintain the concentration of free curcumin in the blood sufficiently high by being administered parenterally, can effectively obtain a pharmacological action of curcumin, and is highly safe. A pharmaceutical composition for parenteral administration, including a water-soluble substance conjugate of curcumin as an active component.
    Type: Application
    Filed: June 28, 2017
    Publication date: July 25, 2019
    Applicants: THERABIOPHARMA INC., KYOTO UNIVERSITY
    Inventors: Hideaki KAKEYA, Masashi KANAI, Nobuaki TAKAHASHI, Tadashi HASHIMOTO, Atsushi IMAIZUMI, Hitomi OZAWA
  • THERAPEUTIC AGENT FOR CANCER
    Publication number: 20170367997
    Abstract: To provide a therapeutic agent for cancer having a higher therapeutic effect. A therapeutic agent for cancer, containing: at least one selected from the group consisting of curcumin and a derivative thereof; and at least one selected from the group consisting of an anti-PD-1 antibody, an anti-PD-L1 antibody, and an anti-PD-L2 antibody in combination.
    Type: Application
    Filed: December 24, 2015
    Publication date: December 28, 2017
    Applicant: THERABIOPHARMA INC.
    Inventors: Yutaka KAWAKAMI, Tomonori YAGUCHI, Taeko HAYAKAWA, Atsushi IMAIZUMI