Patents Assigned to Theraclion
  • Patent number: 10004921
    Abstract: A device (1) and a method for therapeutic treatment comprising an acoustic treatment transducer (2) able to emit high intensity waves (HIFU) toward a target (3) in order to treat the target. The high intensity waves have a focal point. The device com-prises at least one detector (15) for detecting a change of tis-sue properties caused by the high intensity waves in the target (3). The device (1) further comprises at least one means for time measurement able to measure the time tmark from the beginning of the emission of a pulse of HIFU until a change of tissue properties is detected or means for detecting the frequency of appearance of changes of tissue properties.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 26, 2018
    Assignee: Theraclion
    Inventors: Sylvain Yon, Francois Lacoste
  • Patent number: 9433397
    Abstract: To determine the elastic modulus of biologic tissue, a sequence of elasticity images and a sequence of B-mode ultrasound images are acquired simultaneously. Then, at least one sub-sequence of the B-mode ultrasound images representing a resting state is generated from said sequence of B-mode ultrasound images. Based on the sub-sequence of the B-mode ultrasound images, a subsequence of the elasticity images is generated by selecting and/or modifying those elasticity images. Finally, the elastic modulus is determined based on the sub-sequence of the elasticity images. Also disclosed are a method for determining changes of the elastic modulus of a tissue, a method of identifying biological tissue based on the determined elastic modulus and a device for determining the elastic modulus of a biological tissue.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: September 6, 2016
    Assignee: THERACLION
    Inventors: Jérémy Anquez, Francois Lacoste, Sylvain Yon
  • Patent number: 9220659
    Abstract: This invention relates to a coupling liquid for ultrasound devices, preferably high intensity focused ultrasound (HIFU). The coupling liquid comprises a liquid aqueous solution of at least one hydrophilic polymer having an average molecular mass of between 30,000 and 70,000 and at least one alcohol with a carbon chain of 1 to 7 carbon atoms. Also disclosed is a container (10) for an ultrasound coupling liquid having a thin wall.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: December 29, 2015
    Assignee: Theraclion
    Inventors: Roberta Brocardo, Thierry Pechoux
  • Patent number: 8974391
    Abstract: A device for therapeutic treatment includes an acoustic transducer designed to emit power waves to treat a target, and an imaging probe designed to emit waves for providing an image representation of the target and its environment before, during and after the emission of the power waves issuing from the transducer. The probe and the transducer are integrally connected to one another other. The device also includes a display for displaying images taken by the probe, namely images at rest, taken before and/or after emission of the power waves, and interference images, taken during the emission of the power waves. The device additionally comprises a detector for detecting a change of structure of the interference images that is indicative of the efficacy of the power waves.
    Type: Grant
    Filed: August 18, 2009
    Date of Patent: March 10, 2015
    Assignee: Theraclion
    Inventors: Francois Lacoste, Thierry Pechoux
  • Patent number: 8608660
    Abstract: A method of tracing the likely contour of an anatomical element in a sectional image of an anatomical site, the image being composed of pixels having different intensities, the method including the steps of: a) forming columns of pixels passing through the anatomical element; b) assigning each pixel a pixel score representing the probability of the pixel being situated on the contour of the anatomical element; c) constituting a matrix of pixel scores from a plurality of columns of pixels and defining numerous continuous paths of pixels, each passing through a single pixel of each column; d) assigning each continuous path a path score that is a function of the scores of the pixels constituting the continuous path; e) selecting from a set of continuous paths the path that has the best path score, that path representing the likely contour of the anatomical element.
    Type: Grant
    Filed: July 3, 2009
    Date of Patent: December 17, 2013
    Assignees: Theraclion, Centre National de la Recherche Scientifique, Institut National des Sciences Appliquees de Lyon
    Inventors: Didier Vray, Thierry Pechoux
  • Patent number: 8568322
    Abstract: The invention relates to a head for imaging and treating an organ or tissue of a living organism, which is suitable for the treatment of thyroid or prostate tumors. The head comprises: an ultrasound probe for emitting waves or radiation in order to supply an image of the tissue or organ to be treated and a treatment mechanism for treating the tissue or organ locally, where the treatment mechanism emits waves or radiation to treat same. The ultrasonic probe divides the treatment mechanism into two parts that are substantially symmetrically identical in relation to the ultrasonic probe.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: October 29, 2013
    Assignee: Theraclion
    Inventor: François Lacoste
  • Patent number: 8517943
    Abstract: An imaging and treatment head for imaging and treating an organ or tissue of a living being, and usable in particular for treating tumors of the prostate or the thyroid. The head includes an ultrasonic probe suitable for emitting waves or radiation so as to provide an imaged representation of an organ or tissue for treatment. The head also includes a treatment mechanism suitable for treating the organ or tissue locally. The treatment mechanism is suitable for emitting waves or radiation so as to treat the organ or the tissue. The head is characterized in that the ultrasonic probe is mounted in a removable manner on an adapter that ensures positioning of the ultrasonic probe relative to the treatment mechanism.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: August 27, 2013
    Assignee: Theraclion
    Inventor: François Lacoste
  • Publication number: 20130211250
    Abstract: This invention relates to a coupling liquid for ultrasound devices, preferably high intensity focused ultrasound (HIFU). The coupling liquid comprises a liquid aqueous solution of at least one hydrophilic polymer having an average molecular mass of between 30,000 and 70,000 and at least one alcohol with a carbon chain of 1 to 7 carbon atoms. Also disclosed is a container (10) for an ultrasound coupling liquid having a thin wall.
    Type: Application
    Filed: May 16, 2011
    Publication date: August 15, 2013
    Applicant: THERACLION
    Inventors: Roberta Brocardo, Thierry Pechoux
  • Publication number: 20130144162
    Abstract: To determine the elastic modulus of biologic tissue, a sequence of elasticity images and a sequence of B-mode ultrasound images are acquired simultaneously. Then, at least one sub-sequence of the B-mode ultrasound images representing a resting state is generated from said sequence of B-mode ultrasound images. Based on the sub-sequence of the B-mode ultrasound images, a subsequence of the elasticity images is generated by selecting and/or modifying those elasticity images. Finally, the elastic modulus is determined based on the sub-sequence of the elasticity images. Also disclosed are a method for determining changes of the elastic modulus of a tissue, a method of identifying biological tissue based on the determined elastic modulus and a device for determining the elastic modulus of a biological tissue.
    Type: Application
    Filed: November 28, 2012
    Publication date: June 6, 2013
    Applicant: THERACLION
    Inventor: Theraclion
  • Patent number: 8353832
    Abstract: A treatment device and methods for HIFU treatment of thyroid and parathyroid disorders are provided. The treatment method includes steps of identifying a treatment zone and directing high intensity focused ultrasound energy towards the treatment zone. The treatment device has a first sensor for detecting swallowing motion and a second sensor for tracking the motion of the thyroid and parathyroid tissue with ultrasound imaging.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: January 15, 2013
    Assignee: Theraclion
    Inventor: Francois Lacoste
  • Patent number: 8221338
    Abstract: A therapeutic treatment head for treating living tissue (T), the head comprising a casing (1), an ultrasound therapeutic transducer (2) mounted on the casing, and a diaphragm (3) mounted on the casing (1), the diaphragm (3) being designed to come into contact with an application surface (S) of the tissue (T), such as skin; the diaphragm (3), the transducer (2), and the casing (1) together defining a chamber (4) that is filled with an acoustic coupling liquid (L) that flows through the chamber between an inlet (41) and an outlet (42); the transducer (2) being placed in such a manner as to emit ultrasound through a propagation zone (Z) of the chamber towards the diaphragm (3); the head being characterized in that a first temperature sensor (51) is placed close to the inlet (41) and a second temperature sensor (52) is placed close to the outlet (42), the sensors (51, 52) delivering signals that are representative of temperatures.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: July 17, 2012
    Assignee: Theraclion
    Inventors: Francois Lacoste, Thierry Pechoux
  • Publication number: 20110105899
    Abstract: A method of tracing the likely contour of an anatomical element (S, C) in a sectional image of an anatomical site, the image being composed of pixels (Pi) having different intensities, the method comprising the following steps: a) forming columns (K) of pixels (Pi) passing through the anatomical element (S, C), b) assigning each pixel (Pi) a pixel score representing the probability of the pixel being situated on the contour of the anatomical element (S, C), c) constituting a matrix of pixel scores from a plurality of columns (K) of pixels and defining numerous continuous paths of pixels, each passing through a single pixel of each column, d) assigning each continuous path a path score that is a function of the scores of the pixels constituting the continuous path, e) selecting from a set of continuous paths the path that has the best path score, that path representing the likely contour of the anatomical element.
    Type: Application
    Filed: July 3, 2009
    Publication date: May 5, 2011
    Applicants: THERACLION, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
    Inventors: Didier Vray, Thierry Pechoux
  • Publication number: 20100256534
    Abstract: A method for treating a varicose vein comprises heating a dehiscent portion of a wall of the vein so as to produce a localized retraction of collagen. Heating may be via application of high-intensity focused ultrasound energy.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 7, 2010
    Applicants: INSERM, THERACLION
    Inventors: Francois Lacoste, Jean-Yves Chapelon, Olivier Pichot, Réné Milleret, Samuel Pichardo
  • Publication number: 20090299180
    Abstract: A method of determining the real distance between an emitter/receiver face (212) of an imaging probe (2) and a target site, the probe emitting and receiving waves through a propagation medium and living tissue, the method comprising the following successive steps: determining the theoretical distance between the face and the target site when the face is separated from the target site only by the living tissue; determining a distance correction resulting from the fact that the emitted and received waves have passed through the propagation medium; and applying said correction to the theoretical distance so as to obtain the real distance.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 3, 2009
    Applicant: THERACLION
    Inventor: François Lacoste
  • Publication number: 20090216121
    Abstract: An imaging and treatment head for imaging and treating an organ or tissue of a living being, and usable in particular for treating tumors of the prostate or the thyroid, said head comprising: imaging means (2), such as an ultrasonic probe, that are suitable for emitting waves or radiation so as to provide an imaged representation of an organ or tissue for treatment; and treatment means (4) that are suitable for treating said organ or tissue locally, the treatment means being suitable for emitting waves or radiation so as to treat the organ or the tissue; said head being characterized in that the imaging means (2) are mounted in removable manner on an adapter (3; 3?) that ensures positioning of the imaging means (2) relative to the treatment means (4).
    Type: Application
    Filed: June 2, 2006
    Publication date: August 27, 2009
    Applicant: THERACLION
    Inventor: Francois Lacoste