Patents Assigned to Theranos, Inc.
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Publication number: 20140234949Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.Type: ApplicationFiled: January 16, 2014Publication date: August 21, 2014Applicant: Theranos, Inc.Inventors: James Wasson, John Kent Frankovich, Elizabeth A. Holmes, Timothy Smith, Michael Chen, Daniel Young
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Publication number: 20140229955Abstract: Provided herein are medical testing devices, systems, and methods that integrate multiplex, multi-technology, multi-configuration, multisample, or multi-threading capabilities. These capabilities are achieved using one or more of a level operations and communications architecture, a protocol execution engine, and a machine vision and processing system, method, or device in order to make testing of biologic or other samples more efficient in terms of cost, time, energy, or by prioritizing at least one other objective.Type: ApplicationFiled: February 14, 2014Publication date: August 14, 2014Applicant: Theranos, Inc.Inventors: Elizabeth A. Holmes, Daniel Young
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Publication number: 20140222447Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: ApplicationFiled: November 14, 2013Publication date: August 7, 2014Applicant: Theranos, Inc.Inventors: ELIZABETH A. HOLMES, Ian Gibbons, John Howard, Shaunak Roy, Chengwang Wang, Tim Kemp
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Patent number: 8778665Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: GrantFiled: March 30, 2010Date of Patent: July 15, 2014Assignee: Theranos, Inc.Inventors: Ian Gibbons, Shaunak Roy, Edmond Ku
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Publication number: 20140193892Abstract: Methods, devices, apparatus, and systems are provided for image analysis. Methods of image analysis may include observation, measurement, and analysis of images of biological and other samples; devices, apparatus, and systems provided herein are useful for observation, measurement, and analysis of images of such samples. The methods, devices, apparatus, and systems disclosed herein provide advantages over other methods, devices, apparatus, and systems.Type: ApplicationFiled: January 29, 2014Publication date: July 10, 2014Applicant: Theranos, Inc.Inventors: Karan Mohan, Chinmay Pangarkar, James R. Wasson, Elizabeth A. Holmes, Timothy Smith, Samartha Anekal, Daniel L. Young
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Publication number: 20140193806Abstract: The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems and method for detection a plurality of analytes, at least two of which are indicative of an influenza viral infection in a sample of bodily fluid.Type: ApplicationFiled: January 14, 2014Publication date: July 10, 2014Applicant: Theranos, Inc.Inventors: Elizabeth A. Holmes, Ian Gibbons
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Publication number: 20140186238Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.Type: ApplicationFiled: July 1, 2013Publication date: July 3, 2014Applicant: Theranos, Inc.Inventors: Elizabeth Holmes, Joy Roy, John Kent Frankovich
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Publication number: 20140170688Abstract: Reagents, assays, methods, kits, devices, and systems for rapid measurement of cholesterol and cholesterol sub-fractions from a blood sample are provided. Total cholesterol, low density lipoprotein cholesterol, and high density lipoprotein cholesterol can be measured in a single assay using kinetic measurements, under conditions in which cholesterol sub-species are converted to a detectable product at distinct rates. The detectable product is measured at different times after assay initiation. A lipase, cholesterol esterase, cholesterol oxidase and a peroxidase may be used together to produce colored product in amounts directly proportional to the quantity of cholesterol converted. Methods for calculating very-low density lipoprotein cholesterol levels by further including triglyceride measurements are disclosed.Type: ApplicationFiled: December 9, 2013Publication date: June 19, 2014Applicant: Theranos, Inc.Inventors: Douglas Matje, Ian Gibbons, Paul Patel, Elizabeth A. Holmes
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Publication number: 20140171829Abstract: Bodily fluid sample transport systems, devices, and method are provided. In at least one embodiment described herein, methods are provided for the physical transport of small volumes of bodily fluid in liquid form from one location to another location. By way of nonlimiting example, the samples are collected in liquid form at a collection site, transported in liquid form, and arrive at an analysis site in liquid form. In many embodiments, the liquid form during transport is not held in a porous matrix, wicking material, webbing, or similar material that prevents sample for being extracted in liquid form at the destination site. In one embodiment, small volume of sample in each sample vessel is in the range of about 1 ml to about 1 microliter.Type: ApplicationFiled: December 5, 2013Publication date: June 19, 2014Applicant: Theranos, Inc.Inventors: Elizabeth A. Holmes, Clarissa Lui, Michael Chen, Daniel Young
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Publication number: 20140154708Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications. In particular, the medical device reduces interference with an optical signal which is indicative of the presence of an analyte in a bodily sample.Type: ApplicationFiled: June 11, 2013Publication date: June 5, 2014Applicant: Theranos, Inc.Inventors: Ian Gibbons, Michael O'Connell
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Patent number: 8741230Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: GrantFiled: October 30, 2006Date of Patent: June 3, 2014Assignee: Theranos, Inc.Inventors: Elizabeth A. Holmes, Shaunak Roy, Ian Gibbons, Shize Daniel Qi, Edmond Ku, Chris Todd, Melissa Takahashi, Bruce Johnson, Jeff Fenton, Keith Moravick, Uwe Springborn, Anthony Delacruz
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Publication number: 20140114676Abstract: Systems and methods for monitoring and regulating the concentration of a drug in a subject are provided. A method may include administering to a subject a first dose of a pharmaceutical composition at a first time point. Next, a concentration of an active ingredient of the pharmaceutical composition or a metabolite thereof, or a biological marker indicative of the concentration of the pharmaceutical composition in the subject, may be determined from a biological sample of the subject with the aid of a point of care system. A second dose of the pharmaceutical composition may be administered to the subject at a second time point. The second dose and/or the interval between the first and second time points may be determined based on the concentration of the pharmaceutical composition in the subject.Type: ApplicationFiled: October 21, 2013Publication date: April 24, 2014Applicant: THERANOS, INC.Inventor: Elizabeth Holmes
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Publication number: 20140114677Abstract: Methods, systems, devices, and computer-readable media for generating a location-based physiological history of a subject are provided. Methods may include generating, with the aid of a processor, a location-based physiological history of the subject by correlating geolocation data of the subject with physiological data and exogenous data. The geolocation data may be obtained with the aid of a geolocation system on or associated with the subject. The exogenous data may be of or related to environmental conditions at a geographic location of the subject.Type: ApplicationFiled: October 21, 2013Publication date: April 24, 2014Applicant: THERANOS, INC.Inventor: Elizabeth Holmes
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Patent number: 8697377Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.Type: GrantFiled: June 12, 2013Date of Patent: April 15, 2014Assignee: Theranos, Inc.Inventors: Tammy Burd, Ian Gibbons, Elizabeth A. Holmes, Gary Frenzel, Anthony Joseph Nugent
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Publication number: 20140095189Abstract: The disclosure provides methods, systems, and computer readable media for calibrating user responses to questions. The method may comprise presenting, with the aid of a computer system and an interactive display operatively coupled to the computer system, a query to a user. The query may relate to the user's dietary consumption, exercise, health condition or mental condition. The system may receive from the user a response to the query. The system may interpret a user's response to a query based on a set of reference information. The set of reference information may comprise a pictorial depiction of portion size of the dietary consumption, exertion level of the exercise, existing state of the health condition or existing state of the mental condition.Type: ApplicationFiled: September 24, 2013Publication date: April 3, 2014Applicant: Theranos, Inc.Inventor: Elizabeth A. Holmes
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Publication number: 20140087403Abstract: Compositions and methods for measuring coagulation parameters using very small volumes of blood are provided. Advantageously, the methods described herein can be performed from a single drop of blood (about 20 ?L) while generally leaving enough sample to perform other measurements, optionally in a multiplexed format. The methods and devices do not require a skilled operator and can be performed at the point of service, which can be an important feature for managing blood coagulation disorders and treatments thereof.Type: ApplicationFiled: July 17, 2013Publication date: March 27, 2014Applicant: THERANOS, INC.Inventors: Mark Dayel, Samartha Anekal, Paul Patel, Ian Gibbons, Elizabeth Holmes
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Patent number: 8679407Abstract: This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.Type: GrantFiled: March 24, 2006Date of Patent: March 25, 2014Assignee: Theranos, Inc.Inventors: Elizabeth A. Holmes, Ian Gibbons, John Howard, Shaunak Roy, Chengwang Wang, Timothy M. Kemp
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Publication number: 20140081665Abstract: Systems and methods are provided for generating a biological signature such as a genetic signature and using such signature of an individual. The biological signature may be used to verify the identity of the individual. A verified individual may be granted access to a secured location, item, and/or service. Biological signatures may also be used to search or aggregate records for an individual.Type: ApplicationFiled: September 6, 2013Publication date: March 20, 2014Applicant: Theranos, Inc.Inventor: Elizabeth Holmes
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Publication number: 20140073043Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.Type: ApplicationFiled: February 18, 2013Publication date: March 13, 2014Applicant: Theranos, Inc.Inventor: Elizabeth A. Holmes
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Publication number: 20140073990Abstract: Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container.Type: ApplicationFiled: September 6, 2013Publication date: March 13, 2014Applicant: Theranos, Inc.Inventors: Elizabeth A. Holmes, Michael Chen, Pey-Jiun Ko, Tammy Burd, Adrit Lath, Patricia McHale