Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.
Type:
Application
Filed:
June 26, 2008
Publication date:
December 30, 2010
Applicant:
ThERAPEUTIC COMPOSITONS AND USE THEREOF
Inventors:
Brian P. Kearney, Anita A. Mathias, Srinivasan Ramanathan