Abstract: A method of treating inflammation in a mammal, which comprises contacting the affected area with an amount sufficient to ameliorate the inflammatory condition, of a compound of the following formula ##STR1## in a pharmaceutically acceptable carrier containing a detergent, where Z is a substituted phenyl, R is a substituted or unsubstituted alkylsulfonyl group from 1 to 20 carbon atoms and X is --CN, --NO.sub.2, --H, halogen, lower alkyl or lower haloalkyl radical.
Type:
Grant
Filed:
November 4, 1997
Date of Patent:
September 28, 1999
Assignees:
The Research Foundation of State University of New York, Therex Technologies, Inc.
Inventors:
Richard T. Evans, Robert A. Coburn, Robert A. Genco, Joseph A. Dunn