Patents Assigned to Thermo Fisher Scientific Inc.
  • Patent number: 11674847
    Abstract: An embodiment of a system for measuring trace gas concentration is described that comprises a laser absorption spectrometer configured to detect an absorbance measure from a trace gas, as well as a temperature value and a pressure value that correspond to an environment in a gas cell; and a computer having executable code stored thereon configured to perform a method comprising: receiving the absorbance value, the temperature value, and the pressure value; defining a fitting range associated with the trace gas; applying a curve fitting model in the fitting range to the absorbance value using the temperature value and the pressure value as model parameters; and producing a concentration measure of the trace gas.
    Type: Grant
    Filed: November 19, 2019
    Date of Patent: June 13, 2023
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Yongquan Li, Corsino Lopes
  • Patent number: 11614849
    Abstract: A system including a display output device, a computer including instructions that when executed by the computer, cause the computer to generate a virtual environment, instantiate one or more virtual devices into the virtual environment, instantiate a user representation into the virtual environment, and display the virtual environment, the one or more virtual devices, and the user representation on the display output device, an input device to receive a movement input associated with movement by the user representation in the virtual environment, and the computer further configured with instructions to move or rotate the one or more virtual devices relative to a point of reference in the virtual environment in response to the movement input, while maintaining the user representation stationary.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: March 28, 2023
    Assignee: Thermo Fisher Scientific, Inc.
    Inventors: Mark Field, Daniel Garden
  • Publication number: 20220315922
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.
    Type: Application
    Filed: November 5, 2021
    Publication date: October 6, 2022
    Applicant: Thermo Fisher Scientific Inc.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 11198870
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: December 14, 2021
    Assignee: THERMO FISHER SCIENTIFIC INC.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 10920226
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for LDHA.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 16, 2021
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 10809392
    Abstract: An embodiment of a system is described that comprises an ionization chamber electrically coupled with a charge amplifier circuit by a reed switch. The reed switch of the embodiments described herein produces substantially no leakage current and electrically insulates the charge amplifier from the ionization chamber.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: October 20, 2020
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: King L. Poon, Alexander Joseph Esin, Alexei Kulik, Huichun Xing
  • Patent number: 10765695
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for AAT.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: September 8, 2020
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 10696968
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for HAO1.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: June 30, 2020
    Assignee: THERMO FISHER SCIENTIFIC INC.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 10421970
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. Be selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods compositions, and kits generated through rational design of siRNAs are disclosed, including those directed to the nucleotide sequences for COX-2.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: September 24, 2019
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: 10288555
    Abstract: A tamper seal detection system for detecting a sealing sticker on a packaging box includes a housing at least partially bounding an inspection zone, the inspection zone being configured to receive the packaging box. A first sensor is configured to detect the presence of the first sealing sticker located on the packaging box when the packaging box is received within the inspection zone. A push guide is movable relative to the inspection floor between a first position and a spaced apart second position and can be used to push the packaging box out of the inspection zone.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: May 14, 2019
    Assignee: Thermo Fisher Scientific, Inc.
    Inventors: Cody T. Kerschner, Christian S. Heaps, Justin J. Tomel, Shawn M. Regits
  • Patent number: 10233449
    Abstract: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for TTR.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: March 19, 2019
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Anastasia Khvorova, Angela Reynolds, Devin Leake, William Marshall, Steven Read, Stephen Scaringe
  • Patent number: D870739
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: December 24, 2019
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D980233
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: March 7, 2023
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D980234
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: March 7, 2023
    Assignee: Thermo Fisher Scientific, Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1007525
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: December 12, 2023
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1020784
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: April 2, 2024
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1020785
    Type: Grant
    Filed: January 19, 2023
    Date of Patent: April 2, 2024
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1054447
    Type: Grant
    Filed: December 11, 2023
    Date of Patent: December 17, 2024
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1054449
    Type: Grant
    Filed: March 19, 2024
    Date of Patent: December 17, 2024
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips
  • Patent number: D1054450
    Type: Grant
    Filed: March 19, 2024
    Date of Patent: December 17, 2024
    Assignee: Thermo Fisher Scientific Inc.
    Inventors: Krista Lyn Van Guilder, David Scott Phillips