Abstract: The ion trap comprises a multipole electrode assembly, a first confining electrode, and a second confining electrode. The multipole electrode assembly is configured to confine ions of the first polarity to an ion channel extending in an axial direction of the multipole electrode assembly. The first confining electrode is provided adjacent to the multipole electrode assembly and extends in the axial direction of the multipole electrode assembly. The second confining electrode is provided adjacent to the multipole electrode assembly and extends in the axial direction of the multipole electrode assembly aligned with the first confining electrode. The first and second confining electrodes are spaced apart in the axial direction in order to define an ion confining region of the ion channel between the first and second confining electrodes.

Abstract: An ion separation apparatus comprises: (a) first and second ion carpets, each comprising: a substrate having first and second faces; and a set of electrodes disposed on or beneath the first face, wherein a configuration of a first plurality of the set of electrodes defines at least one group of circle sectors; (b) an ion exit aperture passing through one ion carpet; and (c) one or more power supplies configured to provide radio frequency voltages to a first subset of the electrodes of each ion carpet, to provide electrical potential differences across electrodes of the first subset of electrodes of each ion carpet, and to provide time-varying voltages to the first plurality of electrodes of each ion carpet that migrate through the sectors as a traveling wave, wherein the ion carpets are disposed parallel to one another with a gap therebetween, the first faces facing one another across the gap.

Abstract: Packed-tip electrospray ionization (ESI) emitters for mass spectrometry are described. In one aspect an ESI emitter stores a first type of particle. A liquid chromatography (LC) column is coupled with the emitter via a junction. The LC column stores a different type of particle than the ESI emitter to facilitate better chromatographic and ESI performance.

Abstract: An ion mobility analyser is disclosed having a gas flow directed along the ion travel axis and a set of electrodes to which DC voltages are applied to establish a DC field. The opposing forces of the gas flow and DC field cause ions to be trapped within a separation region in axial regions determined by their ion mobilities. A gas recirculator, having inlet and outlet ends respectively located downstream and upstream of the separation region, supplies at least fifty percent of the gas flow within the separation region, thereby reducing vacuum pumping requirements.

Abstract: The present invention relates to a centrifuge, in particular a laboratory centrifuge, comprising a rotor which is rotatably mounted in an interior of a rotor chamber and is designed to accommodate sample vessels, a drive motor to set the rotor in rotation, and a cooling device which is designed to dissipate heat from the interior of the rotor chamber via a coolant, the cooling device being designed to use an elastocaloric effect and having at least one cooling unit which comprises an elastocaloric material arranged between a counter block and a punch, the punch being designed to periodically apply a force to the elastocaloric material and then to let the elastocaloric material relax again, the cooling device being designed to transfer both heat from the elastocaloric material to the coolant and from the coolant to the elastocaloric material. The present invention also relates to a method for cooling an interior of a rotor chamber of such a centrifuge.

Abstract: An ion guide comprising: an ion receiving portion configured to receive ions along a first axis and an ion outlet configured for ejection of ions from the ion guide along a second axis different from the first axis; a deflector electrode configured to receive a DC potential to deflect ions away from the first axis and towards the second axis; and a plurality of electrodes having a substantially planar surface parallel to the second axis and configured to receive RF voltages such that there is a voltage phase difference between adjacent electrodes to generate a RF field thereby, the RF field directing the deflected ions on to the second axis towards the ion outlet.

Abstract: A method for ion activation in an ion guide that comprises a first section and a second section, the second section having a longitudinal axis, the method comprising steps of: receiving ions into the first section of the ion guide at a trajectory that is offset from the longitudinal axis; applying a DC potential gradient in the first section along a dimension that is at a non-zero angle to the longitudinal axis to direct the ions towards the second section and to cause ion activation; and applying an RF field in the second section of the ion guide to confine the ions to the ion guide.

Abstract: A mass spectrometer support apparatus includes a peak shape logic to determine one or more peak shapes using a calibration mass spectrum and known peak locations; and a tuning logic to adjust instrument parameters to achieve a selected peak width. A method for tuning a quadrupole-based mass spectrometer includes determining one or more peak shapes using a calibration mass spectrum and known peak locations; and adjusting instrument parameters to achieve a selected peak width.

Abstract: A method for controlling a mass spectrometer comprising a mass analyser and a detector. A test specimen is supplied into the mass analyser, to travel through the mass analyser and towards the detector, the test specimen comprising a carrier gas and/or analyte ions, the test specimen being one of a series of test specimens to be analysed. An ion intensity is measured, the ion intensity representing the intensity of ions within the test specimen received at the detector. The method determines if at least one validity criterion of a group of validity criteria is complied with, the group of validity criteria including: identification of a valid peak in the ion intensity measured within a predetermined time interval; and identification of a user-specified flag associated with the predetermined time interval. If none of the validity criteria are complied with, then terminating supplying into the mass analyser the test specimen and any further test specimen of the series of test specimens.

Abstract: Determining a level of a liquid in a container is described. In one aspect, a container includes a calibrant liquid used for calibrating a mass spectrometer. A conductive layer is placed to float upon the calibrant liquid, and a circuit board with electrodes is arranged around the container. A controller circuit then drives and measures various electrodes to first identify which two electrodes the level of the calibrant liquid is between, and then subsequently identify a more precise location for the level between the two electrodes.

Abstract: A method of performing mass spectrometry includes obtaining, based on a series of mass spectra of detected ions derived from components eluting from a chromatography column, a plurality of extracted ion chromatograms (XICs), each XIC comprising a plurality of detection points representing detected intensity for a distinct selected m/z as a function of time; detecting, based on the series of mass spectra, precursor ions of each distinct selected m/z of the plurality of XICs; and determining, for each XIC based on a set of detection points of the XIC, a predicted next detection point to be obtained based on a next mass spectrum to be acquired.

Abstract: Methods for operating a mass spectrometer having a skimmer and a circuit configured to apply an electric potential to the skimmer comprise obtaining an initial mass spectrum of a sample and measuring a value indicating an ion beam intensity of one or more ion species. A varying DC electric potential is applied to the skimmer to identify an operational electric potential, wherein the DC electric potential is varied until the value indicating the ion beam intensity of the one or more ion species changes by a predetermined amount. The mass spectrum with the operational electric potential applied to the skimmer is output. In some examples, a pressure within the mass spectrometer is varied to identify an operational pressure, and the mass spectrum with the pressure within the mass spectrometer at the operational pressure is output.

Abstract: An interface system for connecting a vehicle and a transport climate control system (TCCS) is disclosed. The interface system includes a two-way communication interface that connects a vehicle electrical system (VES) controller and a TCCS controller. The interface system also includes a power interface that connects a vehicle energy source of the VES to the TCCS and a TCCS energy source of the TCCS to the VES. The two-way communication interface is configured to distribute a TCCS status from the TCCS controller to the VES controller, and is configured to distribute a VES status from the VES controller to the TCCS controller. The power interface is configured to distribute power from the vehicle energy source to the TCCS when a VES instruction is received, and distribute power from the TCCS energy source to the VES when a TCCS instruction is received.

Abstract: Technologies for enhancing performance of a clutch that is installed in connection with a transport climate control system is provided. Enhancing performance of the clutch can be performed by establishing engagement cycling parameters for the clutch, cycling the clutch through a repetition of engagement and disengagement in accordance with the established engagement cycling parameters, and terminating the cycling upon achievement of at least one predetermined criterion.

Abstract: A personal radiation and density meter system includes a housing, a radiation detection subsystem and a radiation emitting sub-system. The housing includes an interior portion configured as an interior space, and a slot. The radiation detection sub-system includes a personal radiation dosimeter positioned in the slot. The radiation emitting sub-system includes a shield assembly, a source, an actuator, a trigger, and an aperture.

Abstract: An ion mobility analyser comprising an ion guide is provided. The ion guide defines an ion drift channel extending in an axial direction an includes first and second electrode assemblies provided on opposing sides of the ion drift channel. Each of the first and second electrode assemblies extend in the axial direction and in a transverse direction which is transverse to the axial direction. The first and second electrode assemblies are spaced apart on opposing sides of the ion drift channel by a first distance at a narrowest point along the axial direction. Each of the first and second electrode assemblies comprises a set of first electrodes, and a set of second electrodes. The electrodes in the first and second sets are arranged in an alternating pattern in the transverse direction. The alternating pattern extends in the transverse direction a second distance that is greater than the first distance.

Abstract: A component of an ion optical device is manufactured. The component comprises aligned first and second electrode sets. A first material is machined to provide a part-machined first electrode set that comprises the first electrode set attached to a frame part of the first material. A second material is machined to provide a part-machined second electrode set that comprises the second electrode set attached to a frame part of the second material. The component of the ion optical device is assembled by aligning the part-machined first and second electrode sets. Subsequent to aligning the part-machined first and second electrode sets, the part-machined first electrode set is further machined to separate the first electrode set from the frame part of the first material and the part-machined second electrode set is further machined to separate the second electrode set from the frame part of the second material.

Abstract: A transport climate control system for providing climate control to a climate controlled space of a transport unit. The transport climate control circuit includes a compressor, an evaporator and at least two fans. The transport climate control circuit also includes a controller for controlling the transport climate control circuit and for defrosting the evaporator coil. When a defrost event is triggered, the controller instructs the transport climate control circuit to supply heat to or around one section of the evaporator coil, and independently controls each of the at least two fans to move the air around the evaporator coil in a controlled direction so that heat from the one section of the evaporator coil is used to convectively heat the inlet of the evaporator coil.

Abstract: A voltage supply for a mass analyser is provided. The voltage supply comprises a voltage source, a first voltage output, a second voltage output, and a voltage divider network. The first voltage output is configured to provide a first voltage to a first electrode of the mass analyser, wherein the first electrode of the mass analyser has a first mass shift per volt perturbation. The second voltage output is configured to provide a second voltage to a second electrode of the mass analyser, wherein the second electrode of the mass analyser has a second mass shift per volt perturbation. The second mass shift per volt perturbation opposes the first mass shift per volt perturbation. The voltage divider network comprises a first resistor and a second resistor.