Abstract: Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation.

Abstract: Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation.

Abstract: Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation.

Abstract: A system and method for managing pain, configured to be worn by a patient, comprising an electrode array comprising a first electrode and a second electrode for providing a TENS treatment to the patient; a connector configured to couple at least one of the first electrode and the second electrode to an electronics subsystem; a muscle twitch sensor subsystem configured to detect a muscle twitch profile induced by the electrode array at the patient; and an electronics subsystem comprising a power module configured to power the system, a pulse generator coupled to the electrode array and configured to transmit the TENS treatment, and a control module configured to receive an input, from the muscle twitch sensor subsystem, characterizing the muscle twitch profile, wherein the electronics subsystem is configured to modulate a parameter of the TENS treatment based upon the input, until a threshold is satisfied.

Abstract: A system and method for managing pain, configured to be worn by a patient, comprising an electrode array comprising a first electrode and a second electrode for providing a TENS treatment to the patient; a connector configured to couple at least one of the first electrode and the second electrode to an electronics subsystem; a muscle twitch sensor subsystem configured to detect a muscle twitch profile induced by the electrode array at the patient; and an electronics subsystem comprising a power module configured to power the system, a pulse generator coupled to the electrode array and configured to transmit the TENS treatment, and a control module configured to receive an input, from the muscle twitch sensor subsystem, characterizing the muscle twitch profile, wherein the electronics subsystem is configured to modulate a parameter of the TENS treatment based upon the input, until a threshold is satisfied.

Abstract: A system and method for managing pain, configured to be worn by a patient, comprising an electrode array comprising a first electrode and a second electrode for providing a TENS treatment to the patient; a connector configured to couple at least one of the first electrode and the second electrode to an electronics subsystem; a muscle twitch sensor subsystem configured to detect a muscle twitch profile induced by the electrode array at the patient; and an electronics subsystem comprising a power module configured to power the system, a pulse generator coupled to the electrode array and configured to transmit the TENS treatment, and a control module configured to receive an input, from the muscle twitch sensor subsystem, characterizing the muscle twitch profile, wherein the electronics subsystem is configured to modulate a parameter of the TENS treatment based upon the input, until a threshold is satisfied.