Patents Assigned to thinXXS Microtechnology AG
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Patent number: 11453000Abstract: A flow cell and a method for connecting components of a microfluidic flow cell, in particular for integrating component parts into a carrier structure of the flow cell, in which a gap is formed between the components to be connected. The gap is filled with a solvent. The material of at least one component bordering the gap dissolves in the solvent and the material completely fills the width of the gap and partially fills the height thereof after evaporation of the solvent.Type: GrantFiled: May 24, 2019Date of Patent: September 27, 2022Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11364501Abstract: A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.Type: GrantFiled: December 10, 2018Date of Patent: June 21, 2022Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11364500Abstract: A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.Type: GrantFiled: December 10, 2018Date of Patent: June 21, 2022Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11291996Abstract: A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.Type: GrantFiled: December 10, 2018Date of Patent: April 5, 2022Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11071984Abstract: An arrangement including a plurality of carrier elements for a reagent, which is to be introduced into a microfluidic device, in particular a flow cell, via the carrier element, and a holder receiving the plurality of carrier elements. The carrier element is fixed by positive fit in all spatial directions by the holder, keeping at least one region of the carrier element which receives the reagent clear.Type: GrantFiled: December 5, 2017Date of Patent: July 27, 2021Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11045802Abstract: A sample carrier having a region for receiving a sample which is to be analyzed, the volume thereof being between 1-100 ?l, and having an area for handling the sample carrier. The sample carrier is characterized by devices for the fluid-tight placement of the sample carrier together with the sample in an analysis device. An analysis device, in particular a flow cell, includes the sample carrier.Type: GrantFiled: May 11, 2016Date of Patent: June 29, 2021Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 11045804Abstract: A microfluidic flow cell, which has a storage space, which holds liquid reagent material and/or sample material and which is connected to an inlet channel for a fluid that transports the reagent material and/or sample material out of the storage space and to an outlet channel for the reagent material and/or sample material and the fluid. The inlet channel and the outlet channel are connected by a bypass that bypasses the storage space.Type: GrantFiled: May 24, 2017Date of Patent: June 29, 2021Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 10946376Abstract: A carrier element for introducing a dry substance into a cavity of a microfluidic flow cell or a chamber or cavities for interacting with a fluid, including: a plug-like body figure to be insertable into a passage of the flow cell leading to the cavity; and, a carder surface for receiving the drive substance, the carder surface being at an end of the body facing the cavity when the body is inserted in the passage.Type: GrantFiled: February 1, 2019Date of Patent: March 16, 2021Assignee: THINXXS MICROTECHNOLOGY AGInventors: Lutz Weber, Tina Röser
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Patent number: 10898893Abstract: A method for forming a microchannel or microfluidic reservoir is described. Methods provided herein include applying a covering over a recess formed in a substrate and bonding the covering to the substrate along seams. Methods provided herein use a substrate having elevated edge regions bordering the recess that project from the surface of the substrate. Bonding seams nm a distance from the elevated edge regions of the recess such that the covering and the elevated edge regions are pressed against each other. Devices for bonding substrates and coverings to make microchannels and microfluidic reservoirs are also provided herein. Devices provided herein can include pressing elements for holding the substrate and the covering together. Pressing elements provided herein can include recesses and/or elastic layers positioned opposite to one or more recesses in a substrate.Type: GrantFiled: September 10, 2014Date of Patent: January 26, 2021Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 10343158Abstract: A flow cell and a method for connecting components of a microfluidic flow cell, in particular for integrating component parts into a carrier structure of the flow cell, in which a gap is formed between the components to be connected. The gap is filled with a solvent. The material of at least one component bordering the gap dissolves in the solvent and the material completely fills the width of the gap and partially fills the height thereof after evaporation of the solvent.Type: GrantFiled: December 5, 2013Date of Patent: July 9, 2019Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 10232367Abstract: A microfluidic flow cell having a dry substance arranged within the flow cell in a cavity for interaction with a fluid located in the cavity. A passage opens into the cavity and a carrier element that can be inserted into the passage is provided with a carrier surface for the dry substance, adjoining the cavity.Type: GrantFiled: July 4, 2014Date of Patent: March 19, 2019Assignee: THINXXS MICROTECHNOLOGY AGInventors: Lutz Weber, Tina Röser
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Patent number: 10183293Abstract: A reagent reservoir for fluids, including a storage chamber connected to a duct for conducting fluid out of, into and/or through the storage chamber. The duct includes a duct section delimited by a substrate and a film joined to the substrate. The duct is sealed and is openable at a predetermined breaking point by deflecting the film. The film also delimits the storage chamber and covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall, which is formed in the edge portion and runs parallel to the film, determine the surface area of the joining region.Type: GrantFiled: June 22, 2015Date of Patent: January 22, 2019Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 10173215Abstract: A flow cell having at least one storage zone connected to a duct for conducting fluid out of, into or/and through the storage zone. The duct includes a duct section which is delimited by a substrate and a film joined to the substrate and in which the duct is sealed and can be opened at a predetermined breaking point by deflecting the film. The film covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall which is formed in the edge portion and runs parallel to the film determine the surface area of the joining region.Type: GrantFiled: June 22, 2015Date of Patent: January 8, 2019Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Publication number: 20180185841Abstract: A sample carrier having a region for receiving a sample which is to be analyzed, the volume thereof being between 1-100 ?l, and having an area for handling the sample carrier. The sample carrier is characterized by devices for the fluid-tight placement of the sample carrier together with the sample in an analysis device. An analysis device, in particular a flow cell, includes the sample carrier.Type: ApplicationFiled: May 11, 2016Publication date: July 5, 2018Applicant: THINXXS MICROTECHNOLOGY AGInventor: Lutz WEBER
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Publication number: 20170157608Abstract: A flow cell having at least one storage zone connected to a duct for conducting fluid out of, into or/and through the storage zone. The duct includes a duct section which is delimited by a substrate and a film joined to the substrate and in which the duct is sealed and can be opened at a predetermined breaking point by deflecting the film. The film covers a recess in the substrate which forms the duct section. A sealing wall that seals the duct and is integrally joined to the substrate is placed in the recess. The predetermined breaking point is formed by a breakable joining region between the film and an edge portion of the sealing wall facing the film. The dimensions of a peripheral area of the sealing wall which is formed in the edge portion and runs parallel to the film determine the surface area of the joining region.Type: ApplicationFiled: June 22, 2015Publication date: June 8, 2017Applicant: Thinxxs Microtechnology AGInventor: Lutz WEBER
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Patent number: 9644794Abstract: An arrangement composed of a flow cell and an apparatus for operating the flow cell, wherein the flow cell has at least two layers, between which the operator device can produce a cavity structure or alter an existing cavity structure with curvature of at least one of the two layers.Type: GrantFiled: May 27, 2011Date of Patent: May 9, 2017Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 9211538Abstract: The invention relates to a microfluid storage device having at least one supply chamber (5) formed by bulging a film (7) or membrane (19), a target break point (10) for forming an opening in the supply chamber (5), and a transport path (9) leading from the supply chamber (5) to an opening (11) in the supply chamber, for example, an interface between the storage device and a microfluid processing unit (2). According to the invention, the initially closed transport path (9) may be opened to form a transport channel (15) corresponding to the fluid stream escaping from the supply chamber (5), preferably by the escaping fluid itself, which allows the fluid to be removed from the storage device in a bubble-free manner.Type: GrantFiled: December 5, 2008Date of Patent: December 15, 2015Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Publication number: 20150290642Abstract: A flow cell and a method for connecting components of a microfluidic flow cell, in particular for integrating component parts into a carrier structure of the flow cell, in which a gap is formed between the components to be connected. The gap is filled with a solvent. The material of at least one component bordering the gap dissolves in the solvent and the material completely fills the width of the gap and partially fills the height thereof after evaporation of the solvent.Type: ApplicationFiled: December 5, 2013Publication date: October 15, 2015Applicant: thinXXS Microtechnology AGInventor: Lutz Weber
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Patent number: 9149802Abstract: A flow cell with a temperature-control chamber for holding a fluid, the temperature of which is to be controlled, whose boundary wall is formed at least partially by a thin foil for transferring heat between a temperature-control element and the fluid. The foil has several layers joined with one another, such that the layer that faces the fluid is a plastic layer, and at least one other layer is of a metal.Type: GrantFiled: April 3, 2013Date of Patent: October 6, 2015Assignee: THINXXS MICROTECHNOLOGY AGInventor: Lutz Weber
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Patent number: 9108192Abstract: A micro reservoir, particularly for integration in a microfluidic flow cell, with a storage space for receiving a fluid and being in connection with an outlet duct for the fluid, wherein a cancelable lock for the fluid is formed. A mechanism is provided for canceling the lock without pressure of the fluid acting on the lock. The mechanism preferably mechanically destroys the lock.Type: GrantFiled: June 13, 2013Date of Patent: August 18, 2015Assignee: THINXXS MICROTECHNOLOGY AGInventors: Lutz Weber, Michel Neumeier, Stefan Keck