Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.
Type:
Grant
Filed:
January 17, 2017
Date of Patent:
September 10, 2019
Assignee:
Third Eye Diagnostics, Inc.
Inventors:
Terry A. Fuller, William Lai, Anthony Bellezza
Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea.
Abstract: Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods.
Abstract: Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject.
Type:
Grant
Filed:
December 2, 2011
Date of Patent:
July 14, 2015
Assignee:
Third Eye Diagnostics, Inc.
Inventors:
Terry A. Fuller, Yongping Wang, Anthony Bellezza, William Lai