Abstract: The present invention relates to surface modifications and linker attachments. For example, the present invention provides surface modification and linker chemistry that facilitates manufacture and use of microarrays, including nucleic acid and protein microarrays. The present invention also relates to array spotting through non-aqueous liquids.
Type:
Application
Filed:
May 15, 2008
Publication date:
January 29, 2009
Applicant:
Third Wave Technologies
Inventors:
Zbigniev Skrzypcznski, Raymond F. Cracauer, Jeff G. Hall
Abstract: The present invention relates to nucleic acid synthesizers and methods of using and modifying nucleic acid synthesizers. For example, the present invention provides highly efficient, reliable, and safe synthesizers that find use, for example, in high throughput and automated nucleic acid synthesis, as well as methods of modifying pre-existing synthesizers to improve efficiency, reliability, and safety.
Type:
Grant
Filed:
January 26, 2001
Date of Patent:
August 23, 2005
Assignee:
Third Wave Technologies
Inventors:
Raymond F. Cracauer, Zbigniev Skrzypczynski, Ned D. Reimer, Rocky Ganske