Patents Assigned to Thorne, Smith, Astill Technologies, Inc.
  • Assay for determining analyte using mercury release followed by detection via interaction with aluminum
    Patent number: 5108889
    Abstract: An assay employing a tracer comprising a ligand having a mercury label wherein mercury label is released from at least one of a bound or free tracer phase and interacts with a metal. Analyte is determined by a change in at least one property of the metal caused by such interaction. The invention also relates to a device for such an assay wherein mercury ions released from a free or bound tracer are caused to eventually amalgamate with a metal, and the presence and/or amount of analyte is determined by changes in the metal resulting from the eventual amalgamation which may be measured electrically or by other means. The invention also relates to novel assay instruments, novel lancets, assay sensors, assay sensor packets, instrumentation and combinations of assay components, and related methods.
    Type: Grant
    Filed: October 12, 1988
    Date of Patent: April 28, 1992
    Assignee: Thorne, Smith, Astill Technologies, Inc.
    Inventors: Roger E. Smith, Mark E. Astill
  • Medical droplet whole blood and like monitoring
    Patent number: 5047044
    Abstract: An assay employing a tracer comprising a ligand having a mercury label wherein mercury label is released from at least one of a bound or free tracer phase and interacts with a metal. Analyte is determined by a change in at least one property of the metal caused by such interaction. The invention also relates to a device for such an assay wherein mercury ions released from a free or bound tracer are caused to eventually amalgamate with a metal, and the presence and/or amount of analyte is determined by changes in the metal resulting from the eventual amalgamation which may be measured electrically or by other means. The invention also relates to novel assay instruments, novel lancets, assay sensors, assay sensor packets, instrumentation and combinations of assay components, and related methods.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: September 10, 1991
    Assignee: Thorne, Smith, Astill Technologies, Inc.
    Inventors: Roger E. Smith, Mark E. Astill, Jay L. Smith, Gale H. Thorne
  • Medical droplet whole blood and like monitoring
    Patent number: 4995402
    Abstract: An assay employing a tracer comprising a ligand having a mercury label wherein mercury label is released from at least one of a bound or free tracer phase and iunteracts with a metal. Analyte is determined by a change in at least one property of the metal caused by such interaction. The invention also relates to a device for such an assay wherein mercury ions released from a free or bound tracer are caused to eventually amalgamate with a metal, and the presence and/or amount of analyte is determined by changes in the metal resulting from the eventual amalgamation which may be measured electrically or by other means. The invention also relates to novel assay instruments, novel lancets, assay sensors, assay sensor packets, instrumentation and combinations of assay components, and related methods.
    Type: Grant
    Filed: October 12, 1988
    Date of Patent: February 26, 1991
    Assignee: Thorne, Smith, Astill Technologies, Inc.
    Inventors: Roger E. Smith, Mark E. Astill, Jay L. Smith, Gale H. Thorne