Patents Assigned to Thrasos Therapeutics, Inc.
  • Compositions and methods for the treatment of cast nephropathy and related conditions
    Patent number: 9611297
    Abstract: Provided are novel peptides of Formula SEQ ID No. 1: J1CysX1X2X3X4X5X6ProX7ThrCysJ2J3(J4)s(J5)t;?? (SEQ ID No. 1) pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are effective inhibitors of light chains to uromodulin.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: April 4, 2017
    Assignee: Thrasos Therapeutics Inc.
    Inventors: Roger Leger, Gilles Dube, Marie-Elaine Caruso, Jerome Rossert
  • TDF-related compounds and analogs thereof, analogs and bioactive fragments
    Patent number: 8299212
    Abstract: The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing, identifying, and producing molecules, which act as functional modulators of TDF-like receptors. The invention further relates to methods of detecting, preventing, and treating TDF-associated disorders.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: October 30, 2012
    Assignee: Thrasos Therapeutics, Inc.
    Inventors: William D. Carlson, Peter C. Keck, Dattatreymurty Bosukonda, Philippe Bey
  • COMPUTER METHOD AND APPARATUS FOR CLASSIFYING OBJECTS
    Publication number: 20110144916
    Abstract: A computer classification method and apparatus employs statistical analysis of known objects in the class of interest. For each known object in the class, a respective vector of q bits is formed. Each bit indicates presence or absence of an activity or physical property in the object. The probability that a bit is equal to 1 in the class is then applied to vector representations of test objects and determines probability of the test object belonging, to the class.
    Type: Application
    Filed: December 14, 2010
    Publication date: June 16, 2011
    Applicant: THRASOS THERAPEUTICS, INC.
    Inventor: Peter Keck
  • SCREENING METHODS FOR BONE MORPHOGENETIC MIMETICS
    Publication number: 20110081662
    Abstract: Disclosed are methods for identifying agents which modulate the activity of bone morphogenetic protein-7. These methods for identifying agents utilize bone morphogenetic protein receptors, specifically the daf-4 receptor, and more specifically the extracellular domain of the daf-4 receptor. Agents identified by the methods are also described as well as compositions comprising the agents and methods of treating a subject using the agents or compositions.
    Type: Application
    Filed: September 3, 2010
    Publication date: April 7, 2011
    Applicant: THRASOS THERAPEUTICS, INC.
    Inventor: Dattatreymurty Bosukonda
  • TDF-RELATED COMPOUNDS AND ANALOGS THEREOF, ANALOGS AND BIOACTIVE FRAGMENTS
    Publication number: 20100209467
    Abstract: The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing, identifying, and producing molecules, which act as functional modulators of TDF-like receptors. The invention further relates to methods of detecting, preventing, and treating TDF-associated disorders.
    Type: Application
    Filed: September 20, 2006
    Publication date: August 19, 2010
    Applicant: Thrasos Therapeutics , Inc.
    Inventors: William D. Carlson, Peter C. Keck, Michael Sworin, Dattatreymurty Bosukonda, Kellie Watson, Philippe Bey, Romesh Subramanian
  • Tdf-related compounds and analogs thereof
    Publication number: 20100015150
    Abstract: The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing, identifying, and producing molecules which act as functional modulators of TDF-like receptors. The invention further relates to methods of detecting, preventing, and treating TDF-associated disorders.
    Type: Application
    Filed: June 17, 2005
    Publication date: January 21, 2010
    Applicant: Thrasos Therapeutics, Inc.
    Inventors: William D. Carlson, Peter C. Keck, Michael Sworin, Dattatreymurty Bosukonda