Abstract: Systems and methods are provided for regulating access to resources at application run-time. A permissions application is invoked. The permissions application accesses an information store comprising a plurality of permissions. Each such permission is associated with a corresponding resource in a plurality of device resources. The information store specifies which applications have permission to access which device resources. An application is executed on the device and makes a request for a resource while the application is executing. Responsive to the request, the permissions application determines whether the application has run-time access permission to use the resource. When the application has run-time access permission to use the resource, it is granted run-time access to the resource. When the application does not have run-time access permission to use the resource, it is not granted run-time access to the resource but is permitted to continue executing on the device without the requested resource.