Abstract: Methods for the treatment of cancer are described. In particular, methods for treatment of cancer comprising administration of glufosfamide alone or in combination with another anticancer agent are disclosed.
Abstract: Hypoxia activated drug compounds having a structure of formula (I) are useful in the treatment of cancer and other hyperproliferative diseases.
Type:
Grant
Filed:
May 14, 2009
Date of Patent:
November 13, 2012
Assignee:
Threshold Pharmaceuticals
Inventors:
Jason Lewis, Mark Matteucci, Tao Chen, Hailong Jiao