Patents Assigned to ThromboGenies NV
  • Plasminogen and plasmin variants
    Patent number: 9121014
    Abstract: The invention relates to variants of plasminogen and plasmin comprising one or more point mutations in the catalytic domain which reduce or prevent autocatylic destruction of the protease activity plasmin. Compositions, uses and methods of using said variants of plasminogen and plasmin are also disclosed.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: September 1, 2015
    Assignee: ThromboGenies NV
    Inventor: Richard Reinier Zwaal