Patents Assigned to Throwleigh Technologies, L.L.C.
-
Publication number: 20080009443Abstract: The present invention provides a method for the separation of proteins on the basis of molecular weight by use of a multi-segment fractionation chamber based on the principles of diafiltration. In addition, the present invention provides an effective method for the concentration of plasma and recovery of fractions thereof that contain immune factors, clotting factors, and/or albumin. The present invention also provides a plasma diafiltration system and apparatus for the safe preparation of clotting factor concentrates that have broad and practical application to surgery or trauma patients, and patients lacking clotting factors due to inherited diseases or other complication.Type: ApplicationFiled: March 7, 2007Publication date: January 10, 2008Applicant: Throwleigh Technologies, L.L.C.Inventor: Howard Purdum
-
Publication number: 20070138095Abstract: A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels (20). Ultrasonic energy from ultrasonic drivers (42) is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated product. The ultrasonic energy prevents the growth of dendrites on the crystals, resulting in the formation and removal of small crystals of the component to be removed without damage to or removal of the remaining components. Methods and apparatuses for cryoprecipitation and chromatography are also disclosed.Type: ApplicationFiled: February 28, 2007Publication date: June 21, 2007Applicant: Throwleigh Technologies, L.L.C.Inventor: Howard Purdum
-
Patent number: 7118852Abstract: Fluids, such as protein-containing biological fluids, particularly plasma, may be effectively decontaminated by treatment with ultrasonic energy alone or in conjunction with either ozone or UV radiation. Suitable apparatus for decontaminating protein-containing biological fluids with such methods are disclosed.Type: GrantFiled: April 11, 2002Date of Patent: October 10, 2006Assignee: Throwleigh Technologies, L.L.C.Inventor: Howard E. Purdum
-
Publication number: 20050054839Abstract: A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels (20). Ultrasonic energy from ultrasonic drivers (42) is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated product. The ultrasonic energy prevents the growth of dendrites on the crystals, resulting in the formation and removal of small crystals of the component to be removed without damage to or removal of the remaining components. Methods and apparatuses for cryoprecipitation and chromatography are also disclosed.Type: ApplicationFiled: September 21, 2004Publication date: March 10, 2005Applicant: Throwleigh Technologies, L.L.C.Inventor: Howard Purdum
-
Patent number: 6808638Abstract: A method and system (10) for selectively removing one component of a material thereby concentrating other components of the material are disclosed. The material is cooled to below the melting temperature of the material to form a supercooled liquid phase with heat transfer plate with cooling channels (20). Ultrasonic energy from ultrasonic drivers (42) is applied to the material to form solid phase crystals of the component to be removed. These crystals are removed to leave the concentrated products. The ultrasonic energy prevents the growth of dendrites on the crystals, resulting in the formation and removal of small crystals of the component to be removed without damage to or removal of the remaining components. Methods and apparatuses for cryoprecipilation and chromatography are also disclosed.Type: GrantFiled: June 25, 2001Date of Patent: October 26, 2004Assignee: Throwleigh Technologies, L.L.C.Inventor: Howard E. Purdum
-
Publication number: 20030194692Abstract: Fluids, such as protein-containing biological fluids, particularly plasma, may be effectively decontaminated by treatment with ultrasonic energy alone or in conjunction with either ozone or UV radiation. Suitable apparatus for decontaminating protein-containing biological fluids with such methods are disclosed.Type: ApplicationFiled: April 11, 2002Publication date: October 16, 2003Applicant: Throwleigh Technologies, L.L.C.Inventor: Howard E. Purdum
-
Patent number: 5899088Abstract: A system and method for maintaining a temperature sensitive payload within a target temperature range, between a minimum temperature and a maximum temperature. Heat transfer devices are provided, having reservoirs for separately containing a first material and a second material, the materials having distinct and separate phase change temperatures which approximately bracket the target temperature range. The latent heats of transformation related to the respective phase changes of the first and second materials resist heating or cooling of the payload above or below the target temperature range.Type: GrantFiled: May 14, 1998Date of Patent: May 4, 1999Assignee: Throwleigh Technologies, L.L.C.Inventor: Howard E. Purdum