Abstract: [Problem] To provide a cell bank for quickly producing regenerative T cells having an antigen-specific T cell receptor of an individual introduced hereinto, said cell bank containing hematopoietic stem cells differentiated and induced from iPS cells, immature T cells and/or mature T cells as intermediates in the production. [Solution] A cell bank, which contains iPS cells and one or more kinds of cells selected from the group consisting of hematopoietic stem cells differentiated from iPS cells, immature T cells, and mature T cells is constructed. The iPS cells are obtained by initializing peripheral blood mononuclear cells from which B cells and T cells have been removed, or by initializing T cells. The T cell receptor gene is introduced into the hematopoietic stem cells or the immature T cells with the use of a viral vector, a transposon vector, or genome editing techniques. The T cell receptor gene is introduced into the mature T cells with the use of genome editing techniques.

Abstract: Provided is a method for inducing T cells for a cell-based immunotherapy, comprising the steps of: (1) providing Rag 1 and/or Rag 2 gene knockout human pluripotent stem cells bearing genes encoding a T cell receptor specific for a desired antigen, and (2) inducing T cells from the pluripotent stem cells of step (1). Further provided are a cell-based immunotherapy method that uses the T cells for the cell-based immunotherapy and an iPS cell bank for the cell-based immunotherapy.