Patents Assigned to Tianjin Tasly Pharmaceutical Co., Ltd.
  • Publication number: 20120041062
    Abstract: The present invention relates to a new compound of salvianolic acid L, its preparation method, a pharmaceutical composition containing the salvianolic acid L, and its use for preparing a medicament for treating cardio-cerebrovascular diseases.
    Type: Application
    Filed: March 29, 2010
    Publication date: February 16, 2012
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Shuiping Zhou, Wei Li, Yuanpeng Jin, Xiaohui Ma, Jianping Han, Hongfang Cui, Xuejun Luo, Xiaopeng Chen
  • Publication number: 20100136150
    Abstract: The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.
    Type: Application
    Filed: July 28, 2008
    Publication date: June 3, 2010
    Applicant: TIANJIN TASLY PHARMACEUTICAL CO., LTD.
    Inventors: Xiaolin Tong, Yonghong Zhu, Shuiping Zhou, Xiuhui E, Shuangming Wang, Zhongting Xia
  • Publication number: 20100009000
    Abstract: A pharmaceutical granule whose shape is spherical or sphere-like shape with a bulk density of 0.6-1.3 g/ml and a dissolution time of 0.5-5 minutes, which is prepared as follows: mother granules are filled into a fluidized-bed as bed charge; active pharmaceutical ingredients are prepared into a suspension or solution whose viscosity is adjusted to 6.0-9.8 Mpa·S with viscosity adjusting agent; then it is sprayed onto surface of said mother granule to obtain final granule.
    Type: Application
    Filed: June 22, 2007
    Publication date: January 14, 2010
    Applicant: TIANJIN TASLY PHARMACEUTICAL CO. LTD.
    Inventors: Shunnan Zhang, Jianhui Yang, Lina Dong, Hongbo Zhang, Xiaolin Bai, Yan Sun, Ting Li
  • Patent number: 7641922
    Abstract: A process for preparing tanshintotalphenolic acid and the use of the product are disclosed. The process comprises: tanshin is hot-extracted with water, the extract is separated and refined by polyamide column and macroporous adsorption resin column, and lyophilized to obtain tanshintotalphenolic acid. The yield of the final end product is more than 4 percent based on the amount of crude drug and the content of totalphenolic acid is more than 80 percent. The tanshintotalphenolic acid obtained can be used as the medicine for preventing and treating cerebrovascular and cardiovascular diseases and so on.
    Type: Grant
    Filed: May 21, 2003
    Date of Patent: January 5, 2010
    Assignee: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Feng Wei, Hongshui Yue, Dekun Li, Jiangxiao Sun, Zhengliang Ye, Xu Li
  • Publication number: 20090291154
    Abstract: The present invention discloses a pharmaceutical composition comprising Polygonum multiflorum Thunb, which comprises Polygonum multiflorum Thunb, Fructus Crataegi, Salvia miltiorrhiza Bunge and Radix Notoginseng. If needed, the pharmaceutical composition may comprise the pharmaceutically acceptable carriers. The weight ratio of Polygonum multiflorum Thunb, Salvia miltiorrhiza Bunge, Fructus Crataegi and Radix Notoginseng in the present composition is as follows: 10 to 20 parts of Polygonum multiflorum Thunb, 5 to 15 parts of Salvia miltiorrhiza Bunge, 10 to 20 parts of Fructus Crataegi and 1 to 10 parts of Radix Notoginseng. Also, the present invention discloses the methods for preparing the composition, including directly pulverizing the medicines into powder to produce the composition or preparing the medicines into the extracts and then make the extracts into drugs.
    Type: Application
    Filed: December 5, 2005
    Publication date: November 26, 2009
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Xijun Yan, Boli Zhang, Zhixin Guo, Guoguang Zhu, Zhengliang Ye, Feng Wei, Ruizhi Luo
  • Publication number: 20090130203
    Abstract: The present invention relates to plant extracts, specifically, the extracts of Chinese medicine Chenopodium ambrosioides L. and the composition comprising thereof. The extracts of Chinese medicine Chenopodium ambrosioides L. are prepared by conventional methods for the extraction of volatile oil, and can be used to treat Helicobacter Pylori-induced diseases of digestive system, such as gastritis, gastric ulcer, etc., with easy availability of raw materials, simple preparations, prominent effects, and less side-effect.
    Type: Application
    Filed: December 29, 2006
    Publication date: May 21, 2009
    Applicant: Tianjin Tasly Pharmaceutical Co. Ltd.
    Inventors: Feng Wei, Zhengliang Ye, Ju Gao, Chongnian Luo, Dekun Li, Jiangming Chen, Yonghong Zhu, Junfeng Xiong, Xiaoli Zheng, Guangming Zhang, Ying Zhao
  • Publication number: 20080305189
    Abstract: The present invention relates to the treatment of aspirin resistant cardio-cerebrovascular diseases using RSM (RSM), its extract and composition comprising any or both of them, especially the formulation Dan Shen Drop Pills (Drop Pills of RSM).
    Type: Application
    Filed: August 20, 2008
    Publication date: December 11, 2008
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Xijun YAN, Naifeng WU, Zhengliang YE, Xu LI, Zhixin GUO, Na ZHAO
  • Patent number: 7438935
    Abstract: The present invention discloses a pharmaceutical composition for the treatment of cardiovascular and cerebrovascular diseases which comprises Radix Salviae Miltiorrhizae extract 5.0%-70.0%, Radix Notoginseng extract 10.0%-85.0%, Radix Astragali extract 5.0%-70.0%, and Bomeol or oil of Lignum Dalbergiae Odoriferae 1.0%-15.0%. The composition is active against cerebral ischemia and myocardial ischemia. The effects are superior to total phenic acid of Radix Salviae Miltiorrhizae or total saponin of Radix Notoginseng respectively, or the combination thereof. The composition of the invention can provide various kinds of preparations by the addition of various accessories. Thus the invention provides a more effective and convenient composition of TCM effective sections and its preparations.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 21, 2008
    Assignee: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Feng Wei, Dekun Li, Chongnian Luo, Hongshui Yue, Qingchuang Chen, Zhijuan Huang
  • Patent number: 7396545
    Abstract: The present invention discloses a traditional Chinese medicine preparation for cardio-cerebral blood vessel diseases, it is prepared through extracting danshen and Notoginseng by lye, precipitating with alcohol, concentrating, and adding other medicine and excipients. Then using the HAPLY-MS and HAPLY fingerprint Atlas to characterize its Physicochemical properties completely. Using the fingerprint Atlas analysis method of the present invention, the structure and comparative content of biologically active component can be known. Characterization of the physical chemical properties of danshen and Notoginseng of traditional Chinese medicine preparation with this way is better than other methods of the prior art.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: July 8, 2008
    Assignee: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Yiyu Cheng, Haijiang Zhang, Zhengliang Ye
  • Publication number: 20070071837
    Abstract: The present invention relates to the treatment of aspirin resistant cardio-cerebrovascular diseases using RSM (RSM), its extract and composition comprising any or both of them, especially the formulation Dan Shen Drop Pills (Drop Pills of RSM).
    Type: Application
    Filed: August 26, 2004
    Publication date: March 29, 2007
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhengliang Ye, Xu Li, Zhixin Guo, Na Zhao
  • Publication number: 20070059358
    Abstract: The present invention relates to the matrix adjuvants for drop pills and the preparation of the drop pills. The matrix adjuvants for drop pills of the present invention comprise new matrix adjuvants with or without the plastifying components, which are typically natural matrix adjuvants derived from plants and of safety and non-toxicity. The present invention decreases the toxicity caused by polyethylene glycol, alters the situation that adjuvants derived from animals is scarce, improves the quality of drop pills and accelerates the development of drop pills.
    Type: Application
    Filed: February 7, 2004
    Publication date: March 15, 2007
    Applicant: TIANJIN TASLY PHARMACEUTICAL CO., LTD., CHINA
    Inventors: Jianming Chen, Xijun Yan, Yuewu Yang, Wenliang Lu, Yonghong Zhu, Zhengliang Ye, Wei Wang, Guoguang Zhu, Zhigang Zheng, Shuangming Wang
  • Publication number: 20030152651
    Abstract: This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside R1 and ginsenoside Rg1 which are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.
    Type: Application
    Filed: July 31, 2002
    Publication date: August 14, 2003
    Applicant: Tianjin Tasly Pharmaceutical Co., Ltd., China
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu