Patents Assigned to TIBA BIOTECH LLC
  • NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS
    Publication number: 20240093238
    Abstract: Nanoparticle compositions for delivery of nucleic acids to subjects including carriers comprising sugar functionalized nucleic acid carriers, and therapeutic or immunogenic nucleic acid agents enclosed within the delivery molecules are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 21, 2024
    Applicant: TIBA Biotech LLC
    Inventors: Poulami Talukder, Jasdave Chahal
  • Nanoparticle compositions containing sugar functionalized nucleic acid carriers
    Patent number: 11859201
    Abstract: Nanoparticle compositions for delivery of nucleic acids to subjects including carriers comprising sugar functionalized nucleic acid carriers, and therapeutic or immunogenic nucleic acid agents enclosed within the delivery molecules are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: January 2, 2024
    Assignee: TIBA BIOTECH LLC
    Inventors: Poulami Talukder, Jasdave Chahal
  • NANOPARTICLE COMPOSITION FOR THE DELIVERY OF NUCLEIC ACID AGENTS
    Publication number: 20230310645
    Abstract: The present disclosure relates to nanoparticle compositions for delivery of nucleic acid agents. The nanoparticle composition disclosed includes a carrier containing a dendritic polymer skeleton, a PEG moiety, an amine, and a hydrophobic unit. The size of the PEG moiety may be limited, potentially reducing or avoiding anti-PEG antibody induction.
    Type: Application
    Filed: April 3, 2023
    Publication date: October 5, 2023
    Applicant: Tiba Biotech LLC
    Inventors: Poulami Talukder, Maria Varghese
  • CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY
    Publication number: 20230149562
    Abstract: Nanoparticle compositions for delivery of nucleic acids to subjects including carriers comprising polyester (PE) dendrimers or dendrons, and therapeutic or immunogenic nucleic acid agents enclosed within the PE are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided.
    Type: Application
    Filed: April 2, 2021
    Publication date: May 18, 2023
    Applicant: TIBA Biotech LLC
    Inventors: Poulami TALUKDER, Jasdave CHAHAL, Jin HUANG, Karl RUPING
  • NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS
    Publication number: 20230100837
    Abstract: Nanoparticle compositions for delivery of nucleic acids to subjects including carriers comprising sugar functionalized nucleic acid carriers, and therapeutic or immunogenic nucleic acid agents enclosed within the delivery molecules are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 30, 2023
    Applicant: TIBA Biotech LLC
    Inventors: Poulami Talukder, Jasdave Chahal
  • Artificial alphavirus-derived RNA replicon expression systems
    Patent number: 11613561
    Abstract: Synthetic alphavirus-derived replicon expression systems comprising nucleic acid sequences encoding at least one modified nonstructural protein, and synthetic nucleic acid sequences encoding at least one heterologous protein are described. Methods of producing at least one heterologous protein in a cell, or of inducing an immune response in a subject by administering and/or expressing the synthetic alphavirus-derived replicon expression systems are provided.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: March 28, 2023
    Assignee: TIBA BIOTECH, LLC
    Inventors: Jasdave S Chahal, Justine S McPartlan
  • NANOPARTICLE COMPOSITIONS FOR EFFICIENT NUCLEIC ACID DELIVERY AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20210330600
    Abstract: Nanoparticle compositions for delivery of nucleic acids to subjects including modified dendrimers comprising cores, one or more of homogeneous or heterogeneous intermediate and terminal layers, and therapeutic or immunogenic nucleic acid agents enclosed within nanop article compositions are described. Methods for treating or preventing diseases or conditions in a subject by administering the nanoparticle compositions that provide immune responses and synergistic therapeutic or preventive effects are provided.
    Type: Application
    Filed: December 19, 2019
    Publication date: October 28, 2021
    Applicant: TIBA BIOTECH LLC
    Inventors: Poulami TALUKDER, Jasdave CHAHAL, Justine McPARTLAN, Omar KHAN, Karl RUPING