Patents Assigned to TIGA TX, INC.
  • CD20 antibodies
    Patent number: 11414495
    Abstract: CD20 antibodies with improved characteristics. Some embodiments describe antibodies comprising a mouse IgG2; a human IgG1, IgA1 or IgA2 constant region and a variable domain that can bind the epitope “EPANpSEK” (SEQ ID NO:31) on human CD20 expressed on Ramos cells and which antibody has an increased PCD functionality when compared to Rituximab with a constant region of the same isotype.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: August 16, 2022
    Assignee: TIGA TX, INC.
    Inventors: Jeannette Henrica Wilhelmina Leusen, Peter Boross, Johannes Hendrik Marco Jansen, Saskia Meyer