Abstract: The present invention relates to the use of a particular type of adipose tissue derived mesenchymal stem cells (AD-MSCs), which exert immunosuppressive properties, in the manufacture of a pharmaceutical composition for the prevention and treatment of the graft-versus-host disease (GVHD) produced after allogeneic hematopoietic stem cell transplantation.
Type:
Grant
Filed:
December 7, 2006
Date of Patent:
May 14, 2013
Assignees:
Centro de Investigaciones Energéticas, Medioambientales y Technológicas, TiGenix, SA
Inventors:
Manuel Angel González De La Peña, Dirk Büscher, Aitor Beraza Pérez, Juan Bueren Roncero, Rosa Maria Yanez González, Maria Lamana Luzuriaga