Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies of humans. More specifically, the present invention relates to an oncolytic adenoviral vector encoding a bispecific monoclonal antibody. Furthermore, the present invention relates to methods and uses utilizing the oncolytic adenoviral vectors, also together with adoptive cell therapies.
Type:
Grant
Filed:
March 17, 2016
Date of Patent:
November 1, 2022
Assignee:
TILT Biotherapeutics Oy
Inventors:
Akseli Hemminki, Suvi Parviainen, Siri Tähtinen, Ilkka Liikanen, Mikko Siurala
Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies of humans. More specifically, the present invention relates to oncolytic adenoviral vectors alone or together with therapeutic compositions for therapeutic uses and therapeutic methods for cancer. In one aspect the present invention relates to separate administration of adoptive cell therapeutic composition and oncolytic adenoviral vectors. Furthermore, the present invention relates to a pharmaceutical kit and a pharmaceutical composition, both utilizing oncolytic adenoviral vectors.
Type:
Grant
Filed:
November 15, 2016
Date of Patent:
September 29, 2020
Assignee:
TILT Biotherapeutics Oy
Inventors:
Akseli Hemminki, Markus Vähä-Koskela, Siri Tähtinen, Vincenzo Cerullo
Abstract: The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies of humans. More specifically, the present invention relates to oncolytic adenoviral vectors alone or together with therapeutic compositions for therapeutic uses and therapeutic methods for cancer. In one aspect the present invention relates to separate administration of adoptive cell therapeutic composition and oncolytic adenoviral vectors. Furthermore, the present invention relates to a pharmaceutical kit and a pharmaceutical composition, both utilizing oncolytic adenoviral vectors.
Type:
Grant
Filed:
April 16, 2014
Date of Patent:
May 12, 2020
Assignee:
TILT BIOTHERAPEUTICS OY
Inventors:
Akseli Hemminki, Markus Vaha-Koskela, Siri Tahtinen, Vincenzo Cerullo