Patents Assigned to TIRMED PHARMA AB
  • Single stranded oligonucleotides inhibiting endocytosis
    Patent number: 11345916
    Abstract: The invention provides a single-stranded oligonucleotide (ssON) for use in preventing or treating an influenza virus infection in a subject, wherein the single-stranded oligonucleotide is one that inhibits endocytosis. The invention also provides a single-stranded oligonucleotide (ssON) that comprises or consists of a polynucleotide having a sequence sharing at least 60% sequence identity with a sequence of any one of SEQ ID NOs: 13-21 listed in Table 1, or a complementary sequence thereof.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: May 31, 2022
    Assignee: TIRMED PHARMA AB
    Inventors: Peter Järver, Anna-Lena Marie Spetz, Aleksandra Maria Dondalska
  • Single-stranded oligonucleotides for use in the medical treatment of skin disorders
    Patent number: 10626401
    Abstract: The invention relates to non-CpG single-stranded oligonucleotides (ssONs) for use in the treatment or prophylaxis of disorders of the skin and/or subcutaneous tissue, including pruritus, in a suitable formulation or in combination with other immunomodulatory treatments. The said ssONs have a length of at least 25 nucleotides and are stabilized by phosphorothioate internucleotide linkages and/or 2?-O-Methyl modifications.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: April 21, 2020
    Assignee: TIRMED PHARMA AB
    Inventors: Anna-Lena Spetz, Peter Jarver, Annette Skold