Patents Assigned to Tisento Therapeutics Inc.
  • sGC stimulators
    Patent number: 11897887
    Abstract: The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts, pharmaceutical formulations comprising them as well as their phosphate ester prodrugs, and their uses alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or the upregulation of the NO pathway is desirable. The compounds are of Formula I.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: February 13, 2024
    Assignee: Tisento Therapeutics Inc.
    Inventors: Glen Robert Rennie, Paul Allan Renhowe, Takashi Nakai, Ara Mermerian, Helen Cumberbatch