Abstract: A composition comprising a pre-polymer having activated and functionalized groups on a polymeric backbone is disclosed. The composition may be used in a method of adhering or sealing tissue, or for adhering a medical device to the surface of a tissue. The composition has improved adhesive and sealant properties and comprises a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n. A represents a substituted or unsubstituted polyol, B represents a substituted or unsubstituted polyacid, and n represents an integer greater than 1. Additionally, the composition has a zeta potential in the range of 0 to 45 mV.

Abstract: A composition with improved adhesive and sealant properties comprises a) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1; wherein the content of grafted anhydride in the composition is less than 0.05 mol/mol of polyacid.

Abstract: A composition with improved adhesive and sealant properties comprising a pre-polymer comprising a polymeric unit of the general formula (1A1B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1, wherein the compositions has a grafted anhydride content of less than about 0.05 mol/mol of polyacid.

Abstract: A composition with improved adhesive and sealant properties comprising a) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1, and b) an anhydride compound.

Abstract: A 3D printing resin composition for a biomaterial and method for 3D printing the composition are disclosed. The composition comprises: (i) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1, (ii) at least one photo-initiator, and (iii) at least one light blocker.