Abstract: A device, kit, and method for aspirating graft tissue and delivering the graft tissue to a target delivery site. An injector comprises a cylinder and a plunger that is both linearly and rotatably advanceable and retractable within the cylinder. A kit comprises an injector, a cartridge, and a cartridge coupling element that connects the cartridge to the injector. The kit may also include a container that is configured to retain a cartridge and to facilitate connection between the injector and the cartridge. The container includes at least one fluid barrier that prevents spillage of storage solution from the container when the injector is at least partially inserted into the well of the container.
Type:
Grant
Filed:
September 1, 2021
Date of Patent:
September 17, 2024
Assignees:
TissueCor, LLC, University of Miami
Inventors:
Alfonso L. Sabater, William B. Buras, Alejandro M. Sabater, Daniel J. Duminuco, Michael A. Botta
Abstract: A device and method for aspirating graft tissue and delivering the graft tissue to a target delivery site (for example, when performing Descemet's membrane endothelial keratoplasty). In one embodiment, an injector comprises a cylinder and a plunger at least partially located within the cylinder, the plunger being rotatably advanceable and retractable within the cylinder. In one aspect of the embodiment, rotating the plunger in a first direction within the cylinder controllably aspirates a graft tissue into the injector and rotating the plunger in a second direction opposite the first direction controllably ejects the graft tissue from the injector.
Type:
Grant
Filed:
February 28, 2020
Date of Patent:
April 16, 2024
Assignees:
TissueCor, LLC, University of Miami
Inventors:
Alfonso L. Sabater, Abhishek Shah, William B. Buras, Alejandro M. Sabater
Abstract: A device and method for preserving corneal graft tissue. In one embodiment, a device for preserving corneal graft tissue comprises: a first chamber; a second chamber; and a corneal graft tissue suspension assembly that is configured to retain and suspend the corneal graft tissue between the first chamber and the second chamber, the first chamber being fluidly isolated from the second chamber when the corneal graft tissue is graft tissue is retained and suspended within the corneal graft tissue suspension assembly. In one embodiment, a method includes filling a first chamber of a device with a first preservation medium and filling a second chamber of the device with a second preservation medium different than or the same as the first, a corneal graft tissue being located between the first and second chambers.
Type:
Grant
Filed:
September 14, 2019
Date of Patent:
October 26, 2021
Assignees:
University of Miami, TissueCor, LLC
Inventors:
Alfonso L. Sabater, Alejandro M. Sabater, William B. Buras