Patents Assigned to TM Innovation
  • Process for the preparation of human factor VIII and analogs of factor VIII
    Patent number: 5707832
    Abstract: The present invention relates to a process for the preparation of factor VIII or an analog of factor VIII by culture, in a culture medium, of cells which produce said factor VIII or analog of factor VIII and the separation of factor VIII or its analog, wherein the culture medium contains at least one derivative of a polycationic and/or polyanionic polymer.It also relates to factor VIII or analog of factor VIII and to the complex of factor VIII or analog of factor VIII with a derivative of a polycationic and/or polyanionic polymer obtained by using this process.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: January 13, 1998
    Assignee: TM Innovation
    Inventors: Gerard Mignot, Nicolas Bihoreau, Philippe Adamowicz
  • Process for the preparation of human factor VIII and analogs of factor VIII
    Patent number: 5422250
    Abstract: The present invention relates to a process for the preparation of factor VIII or an analog of factor VIII by culture, in a Culture medium, of cells which produce said factor VIII or analog of factor VIII and the separation of factor VIII or its analog, wherein the culture medium contains at least one derivative of a polycationic and/or polyanionic polymer.It also relates to factor VIII or analog of factor VIII and to the complex of factor VIII or analog of factor VIII with a derivative of a polycationic and/or polyanionic polymer obtained by using this process.
    Type: Grant
    Filed: November 3, 1992
    Date of Patent: June 6, 1995
    Assignee: TM Innovation
    Inventors: Gerard Mignot, Nicholas Bihoreau, Philippe Adamowicz