Abstract: A thermophilic microorganism comprising a modification that prevents sporulation, wherein the modification inactivates the native spo0A gene.
Type:
Grant
Filed:
February 26, 2013
Date of Patent:
October 18, 2016
Assignee:
TMO RENEWABLES LIMITED
Inventors:
Anthony Atkinson, Kirstin Eley, Roger Cripps
Abstract: A thermophilic microorganism is modified to permit the increased production of ethanol, wherein a first modification is the inactivation of the lactate dehydrogenase gene and a second modification upregulates the pyruvate dehydrogenase gene.
Type:
Grant
Filed:
September 28, 2007
Date of Patent:
January 13, 2015
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Brian Rudd, Kirstin Eley, Steve Martin, Paul Milner, Claire Mercier
Abstract: A thermophilic micro-organism comprising a modification that increases amylase expression and starch hydrolysis compared to wild-type, wherein the modification is insertion of a heterologous amylase gene.
Type:
Grant
Filed:
January 25, 2012
Date of Patent:
October 7, 2014
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley, Brian Rudd, Martin Todd
Abstract: Modified microorganisms are prepared by inactivation of the endogenous lactate dehydrogenase gene. The microorganisms are deposited under NCIMB Accession Nos. 41277, 41278, 41279, 41280 or 41281.
Type:
Grant
Filed:
June 7, 2006
Date of Patent:
September 24, 2013
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Ann Thompson, Kirstin Eley, Mark Taylor, David Leak, Brian Rudd, Simon Baker
Abstract: A thermophilic microorganism comprising a modification that prevents sporulation, wherein the modification inactivates the native spo0A gene.
Type:
Grant
Filed:
November 5, 2009
Date of Patent:
July 16, 2013
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley
Abstract: A thermophilic micro-organism comprising a modification that increases amylase expression and starch hydrolysis compared to wild-type, wherein the modification is insertion of a heterologous amylase gene.
Type:
Application
Filed:
January 25, 2012
Publication date:
March 7, 2013
Applicant:
TMO RENEWABLES LIMITED
Inventors:
ANTHONY ATKINSON, Roger Cripps, Kirstin Eley, Brian Rudd, Martin Todd
Abstract: A thermophilic micro-organism comprising a modification that increases amylase expression and starch hydrolysis compared to wild-type, wherein the modification is insertion of a heterologous amylase gene.
Type:
Grant
Filed:
July 26, 2011
Date of Patent:
March 27, 2012
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley, Brian Rudd, Martin Todd
Abstract: A thermophilic micro-organism comprising a modification that increases amylase expression and starch hydrolysis compared to wild-type, wherein the modification is insertion of a heterologous amylase gene.
Type:
Grant
Filed:
August 12, 2008
Date of Patent:
September 20, 2011
Assignee:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley, Brian Rudd, Martin Todd
Abstract: A thermophilic microorganism comprising a modification that prevents sporulation, wherein the modification inactivates the native spo0A gene.
Type:
Application
Filed:
November 5, 2009
Publication date:
September 8, 2011
Applicant:
TMO Renewables, Limited
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley
Abstract: A thermophilic micro-organism comprising a modification that increases amylase expression and starch hydrolysis compared to wild-type, wherein the modification is insertion of a heterologous amylase gene.
Type:
Application
Filed:
August 12, 2008
Publication date:
August 18, 2011
Applicant:
TMO RENEWABLES LIMITED
Inventors:
Anthony Atkinson, Roger Cripps, Kirstin Eley, Brian Rudd, Martin Todd
Abstract: A thermophilic microorganism is modified to permit the increased production of ethanol, wherein a first modification is the inactivation of the lactate dehydrogenase gene and a second modification upregulates the pyruvate dehydrogenase gene.
Type:
Application
Filed:
September 28, 2007
Publication date:
July 8, 2010
Applicant:
TMO Renewables Limited
Inventors:
Anthony Atkinson, Roger Cripps, Brian Rudd, Kirstin Eley, Steve Martin, Paul Milner, Claire Mercier