Patents Assigned to Tokai University
  • Patent number: 7205519
    Abstract: A confocal microscope apparatus has a confocal scanner for scanning a sample with shifting a focal position of a light beam in a direction perpendicular to an optical axis, a moving mechanism for moving the focal position of the light beam in an optical axis direction, a camera for picking up an image of the sample with the light beam, and a movement control unit for controlling the moving mechanism to move the focal position of the light beam by a predetermined distance in the optical axis direction for every vertical synchronizing signal of the camera in synchronization with the vertical synchronizing signal. A high-speed three-dimensional image can be displayed in such that while measuring the sample, two or more slice images in such an arrangement on a common screen that their positions relative to the sample enables to be grasped.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: April 17, 2007
    Assignees: Tokai University Educational System, Yokogawa Electric Corporation
    Inventors: Hideyuki Ishida, Takeo Tanaami
  • Publication number: 20070073196
    Abstract: An apparatus generates a cutaneous sense stimulus to call a subject attention to a change in posture based on posture change information (the amount of change in the barycenter, a changing direction of the same, and the like) from a device for detecting a change in posture of the subject. The apparatus has stimulus generating means (a plurality of vibrators) for generating a cutaneous sense stimulus, and stimulus control means for driving the stimulus generating means based on the posture change information. The control means comprises means for selecting a plurality of vibrators arranged substantially parallel with the changing direction based on the changing direction of the barycenter, and sequentially driving the selected vibrators, for example, in a direction substantially opposite to the direction in which the barycenter changes. The control means also drives the vibrators to generate the tactile sense stimulus of a magnitude corresponding to a changing amount of the barycenter.
    Type: Application
    Filed: May 21, 2004
    Publication date: March 29, 2007
    Applicants: Hokkaido Technology Licensing Office Co., Ltd., Tokai University Educational System, Kyowa Electronic Instruments Co., Ltd.
    Inventors: Toshiaki Tanaka, Takashi Izumi, Takeshi Tsuruga, Akinori Omura
  • Patent number: 7169407
    Abstract: The present invention provides agents that decrease carbonyl stress comprising biguanides, such as metoformin. Through oral administration and such, the carbonyl stress-decreasing agents of the present invention are useful as drugs directly acting against carbonyl stress in vivo.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: January 30, 2007
    Assignees: Kiyoshi Kurokawa, Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 7132692
    Abstract: An object of the present invention is to allow the three primary colors of light (red, green, blue) to be emitted, and particularly to allow blue light to be emitted clearly and in a stable manner at a low voltage. An amorphous SiOx film 2 consisting of a mixture of silicon atoms and oxygen atoms is formed on a semiconductor substrate 1. The result is heat treated in an inert gas to form the silicon atoms into nanosilicon 4a of about 3.0 nm or less. The result is subjected to hydrofluoric acid aqueous solution treatment 5 and thermal oxidation treatment 6. Any of the three primary colors of light, particularly blue, can be emitted at a low operating voltage 7 at room temperature.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: November 7, 2006
    Assignee: Tokai University Educational System
    Inventors: Tomio Izumi, Keisuke Sato, Mitsuo Iwase
  • Publication number: 20060192076
    Abstract: A confocal microscope apparatus has a confocal scanner for scanning a sample with shifting a focal position of a light beam in a direction perpendicular to an optical axis, a moving mechanism for moving the focal position of the light beam in an optical axis direction, a camera for picking up an image of the sample with the light beam, and a movement control unit for controlling the moving mechanism to move the focal position of the light beam by a predetermined distance in the optical axis direction for every vertical synchronizing signal of the camera in synchronization with the vertical synchronizing signal. A high-speed three-dimensional image can be displayed in such that while measuring the sample, two or more slice images in such an arrangement on a common screen that their positions relative to the sample enables to be grasped.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 31, 2006
    Applicants: TOKAI UNIVERSITY EDUCATIONAL SYSTEM, JAPAN SCIENCE AND TECHNOLOGY AGENCY, YOKOGAWA ELECTRIC CORPORATION
    Inventors: Hideyuki Ishida, Takeo Tanaami
  • Publication number: 20060192075
    Abstract: A confocal microscope apparatus has a confocal scanner for scanning a sample with shifting a focal position of a light beam in a direction perpendicular to an optical axis, a moving mechanism for moving the focal position of the light beam in an optical axis direction, a camera for picking up an image of the sample with the light beam, and a movement control unit for controlling the moving mechanism to move the focal position of the light beam by a predetermined distance in the optical axis direction for every vertical synchronizing signal of the camera in synchronization with the vertical synchronizing signal. A high-speed three-dimensional image can be displayed in such that while measuring the sample, two or more slice images in such an arrangement on a common screen that their positions relative to the sample enables to be grasped.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 31, 2006
    Applicants: TOKAI UNIVERSITY EDUCATIONAL SYSTEM, JAPAN SCIENCE AND TECHNOLOGY AGENCY, YOKOGAWA ELECTRIC CORPORATION
    Inventors: Hideyuki Ishida, Takeo Tanaami
  • Patent number: 7072732
    Abstract: A computer solves an item-based one-dimensional sub-optimization problem independently of the other items. For the item-based solution found, the computer determines whether machine interference between the items is eliminated and whether a work-in-process inventory is sufficient. If machine interference is not eliminated or the work-in-process inventory is not insufficient, then the computer updates a corresponding Lagrange multiplier and reexecutes the solving of the problem.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: July 4, 2006
    Assignees: Tokai University Educational System, Information and Mathematical Science Laboratory
    Inventors: Kenji Muramatsu, Aditya Warman, Minoru Kobayashi, Takuya Yamaguchi
  • Patent number: 7029906
    Abstract: Carbonyl stress-ameliorating agents have been provided, which contain an enzyme having a glyoxalase I activity and a carbonyl compound-reducing agent as the active ingredients. The carbonyl stress-ameliorating agents of the present invention rapidly eliminate carbonyl compounds, and thus ameliorate carbonyl induced stress conditions.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: April 18, 2006
    Assignees: Tokai University Education System
    Inventor: Toshio Miyata
  • Patent number: 7026126
    Abstract: The present invention provides a method for evaluating renal functions by measuring megsin protein in a biological specimen. Moreover, the present invention provides immunological assay reagents, as well as kits useful for the measurement of megsin protein in the biological specimen.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 11, 2006
    Assignees: Tokai University Educational System, Fuso Pharmaceutical Industries, Ltd.
    Inventor: Toshio Miyata
  • Publication number: 20060041160
    Abstract: A compound of the invention is a specific compound having a phosphorylcholine group, and a polymer of the invention comprises at least 1 mol % of repeating units with a phosphorylcholine group and has a number-average molecular weight of 1,000 or more, the repeating units with a phosphorylcholine group being represented by the formula (II): wherein A is a bond selected from a single bond, —O—, —COO—, —OOC—, —CONH—, —NH—, —NHCO—, —NR2— and —CH2O— where R2 is an alkyl group having 1 to 6 carbon atoms; and m is an integer of 1 to 12.
    Type: Application
    Filed: February 18, 2004
    Publication date: February 23, 2006
    Applicant: Tokai University
    Inventors: Yu Nagase, Masataka Oku, Kazuhiko Ishihara, Yasuhiko Iwasaki
  • Patent number: 6987906
    Abstract: An optical connection device according to the invention is an optical connection device for optically coupling light propagated through an optical waveguide to an optical element arranged outside the optical waveguide and with the following configuration. Part of the optical waveguide is removed so as to be shaped like a groove. The optical waveguide and the optical element are arranged so that an optical axis of the optical waveguide intersects an optical axis of the optical element at a specified angle inside the groove. An optical unit is arranged at a position of intersection of the optical axes for turning light by reflection from one optical axis along the other optical axis.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: January 17, 2006
    Assignees: Nippon Sheet Glass Co., Ltd., Tokai University Educational System
    Inventors: Kenichi Nakama, Yukinari Sekiguchi, Osamu Mikami, Yoshikazu Murata, Kentarou Miyazato
  • Patent number: 6986412
    Abstract: A tuned cradle type damping deice which can be tuned with low-order (e.g., 1 Hz or lower) vibration, and exhibits higher performance for maintenance and inspection with a simple constitution than a conventional one. This tuned cradle type damping device comprises: a support having a circular-arc support surface which is at least a part of a circle; two swings positioned on both outsides of a center axis extending direction of the circular-arc support surface of the support; and two rollers which are rotatably supported on the circular-arc support surface to be rolled thereon and moved around the center axis thereof, and both ends of which are rotatably connected to the two swings to support the two swings.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: January 17, 2006
    Assignees: Tokai University Educational Systems, Nippon Comsys Corporation
    Inventors: Yoji Shimazaki, Morio Obata, Wataru Morijiri
  • Patent number: 6974309
    Abstract: A Straight blade type turbine has at least one two-dimensional blade positioned in parallel with and around a central axis of the turbine. The two-dimensional blade has a cross section with a blade chord turned around a center of the two-dimensional blade by an angle of 3° to ?2° relative to a line perpendicular to another imaginary line connecting the central axis with the center of the two-dimensional blade. A distance between a fore end and the center of the cross section is 15 to 40 percent of a chord length of the blade. NC/R, which is calculated by a radius R extending from the axis to the center of two-dimensional blade, the chord length C, and the number N of the two-dimensional blades, is between 0.5 and 2.2. A maximum thickness of the two-dimensional blade is between 20 and 25 percent of the chord length.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: December 13, 2005
    Assignee: Tokai University Educational System
    Inventor: Kazuichi Seki
  • Publication number: 20050232843
    Abstract: A method of producing an aggregate of hollow or solid carbon fibers is provided which comprises the step of (i) heating a solution comprising carbon, oxygen, hydrogen, and sulfur as components; or (ii) heating a vapor of a solution comprising carbon, oxygen, hydrogen, and sulfur as components in an atmosphere of a saturated vapor of the solution.
    Type: Application
    Filed: August 26, 2004
    Publication date: October 20, 2005
    Applicants: CANON KABUSHIKI KAISHA, TOKAI UNIVERSITY EDUCATIONAL SYSTEM
    Inventors: Teigo Sakakibara, Yoichi Hirose
  • Publication number: 20050214459
    Abstract: An object of the present invention is to provide methods of easily producing a diamond and an aggregated carbon fiber. The methods of the present invention are methods of producing a diamond and an aggregated carbon fiber used by heat treatment vapor of a carbon source in the absence of air, the methods including the following steps (i) and (iii) of, the following steps (ii) and (iii) of, or the following steps (i), (ii) and (iii) of: (i) heating a liquid containing at least carbon, oxygen and hydrogen as components in a vessel from an outside of the vessel to exhaust air in the vessel by means of vapor of the liquid; (ii) introducing a gas into a vessel storing the liquid containing at least carbon, oxygen and hydrogen as components to exhaust air in the vessel; and (iii) heating the vapor of the liquid containing at least carbon, oxygen and hydrogen as components in an atmosphere of the saturated vapor of the liquid.
    Type: Application
    Filed: March 17, 2005
    Publication date: September 29, 2005
    Applicants: CANON KABUSHIKI KAISHA, TOKAI UNIVERSITY EDUCATIONAL SYSTEM
    Inventors: Teigo Sakakibara, Yoichi Hirose
  • Patent number: 6919326
    Abstract: Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be eliminated by pre-contacting with the trapping agent. Further, it is possible to eliminate carbonyl compounds transferred from the blood to the peritoneal cavity of the patient during peritoneal dialysis treatment, by adding the trapping agent to the peritoneal dialysate or by circulating the fluid through a carbonyl compound-trapping cartridge. Intraperitoneal protein modification by carbonyl compounds is inhibited by the present invention, thereby sufficiently reducing peritoneal disorders associated with peritoneal dialysis treatment.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: July 19, 2005
    Assignees: Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 6913435
    Abstract: In an integrated vane 1 for use in wind or water, main blades 3 arranged around an axial shaft 2 of the vane and support blades 4 for joining the main blades to the axial shaft are integrally formed with light and high strength fiber material such as glass fibers and carbon fibers. The main blade is symmetrical or asymmetrical in its cross sectional view and the support blade is symmetrical in its cross sectional view. The upper support blade may be asymmetrical in its cross sectional view and the lower support blade may have an up-and-down reversed shape of that of the upper support blade. A mountain-shaped portion may be formed at the ends of the main blade for reducing noise. The strength of crossing portions between the main and support blade of the vertical axis vane for use in wind or water is thus improved.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: July 5, 2005
    Assignee: Tokai University Educational System
    Inventor: Kazuichi Seki
  • Patent number: 6899678
    Abstract: The present invention aims to provide a puncture difficulty evaluating device which can readily evaluate the difficulty of puncture in a measuring point. To this end, a puncture difficulty device receives the ultrasound backscattered at the measurement point, determines an integral of the power of the ultrasound over a predetermined angle range, and generates a parameter indicating the difficulty of puncture in the measurement point based on the determined integral.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: May 31, 2005
    Assignees: Tokai University Educational System, Medico's Hirata Inc.
    Inventors: Takaki Shimura, Yasuharu Nimura, Wataru Yoshioka
  • Publication number: 20050051401
    Abstract: There is disclosed a tuned cradle type damping deice which can be A, tuned with low-order (e.g., 1 Hz or lower) vibration, and exhibits higher performance for maintenance and inspection with a simple constitution than a conventional one. This tuned cradle type damping device comprises: a support having a circular-arc support surface which is at least a part of a circle; two swings positioned on both outsides of a center axis extending direction of the circular-arc support surface of the support; and two rollers which are rotatably supported on the circular-arc support surface to be rolled thereon and moved around the center axis thereof, and both ends of which are rotatably connected to the two swings to support the two swings.
    Type: Application
    Filed: March 9, 2004
    Publication date: March 10, 2005
    Applicants: TOKAI UNIVERSITY EDUCATIONAL SYSTEM, NIPPON COMSYS CORPORATION
    Inventors: Yoji Shimazaki, Morio Obata, Wataru Morijiri
  • Publication number: 20050050810
    Abstract: There is disclosed a prop-type damping deice which effectively consumes energy of up-and-down vibration on a main girder of a bridge caused by earthquakes, winds, passing vehicles or the like to prolong a life of the bridge and improve comfort for bridge users with a simple constitution. The prop-type damping device comprises: an inclined prop member having a higher end thereof connected to a lower part of a main girder of a bridge to be horizontally movable relative to the same, and a lower end thereof connected to a position below a main girder supporting point of a pier or abutment for supporting the main girder to permit up-and-down movement of the higher end; and a damper connected to the higher end of the prop member and the main girder lower part to brake relative horizontal movements therebetween.
    Type: Application
    Filed: March 9, 2004
    Publication date: March 10, 2005
    Applicants: TOKAI UNIVERSITY EDUCATIONAL SYSTEM, NIPPON COMSYS CORPORATION
    Inventors: Yoji Shimazaki, Morio Obata, Wataru Morijiri