Patents Assigned to Tokyo Metropolitan Government
  • Publication number: 20230024068
    Abstract: The present invention provides a prophylactic or therapeutic composition for graft-versus-host disease (GVHD). There is provided a prophylactic or therapeutic composition for GVHD, which comprises bacteria belonging to any genus selected from the group consisting of the following genera: Blautia, Clostridium, unclassified Clostridiales, Actinomyces, Parabacteroides, Lachnoclostridium, Bacteroides, Faecalibacterium, unclassified Lachnospiraceae, Roseburia, Ruminococcus, unclassified Firmicutes, Dorea, Phascolarctobacterium, Sutterella, Megamonas, Collinsella, Eubacterium, and Coprococcus, etc., or any combination of bacteria belonging to these genera.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Applicants: JSR CORPORATION, TOKYO METROPOLITAN GOVERNMENT, KEIO UNIVERSITY
    Inventors: Kazuhiko KAKIHANA, Kyoko INAMOTO, Kenya HONDA, Kozue TAKESHITA, Yuuko KIRIDOOSHI
  • Patent number: 11371982
    Abstract: The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: June 28, 2022
    Assignees: TOSOH CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Yasuyuki Akiyama, Atsushi Morimoto, Toru Futami, Fumiaki Koizumi, Takeshi Sawada
  • Patent number: 10788447
    Abstract: A liquid analyzer is one that performs analysis in a state of being immersed in a flowing analysis target liquid, and in order to simply make a good/bad determination and increase reliability, includes: a sensor adapted to, in a state where a responsive membrane is immersed in the flowing analysis target liquid, sense a predetermined component contained in the analysis target liquid; an analysis mechanism adapted to analyze the analysis target liquid with use of voltage generated in the sensor; and a resistance measurement mechanism adapted to, in the state where the responsive membrane is immersed in the flowing analysis target liquid, apply DC voltage to the responsive membrane to measure the resistance of the responsive membrane.
    Type: Grant
    Filed: November 26, 2015
    Date of Patent: September 29, 2020
    Assignees: HORIBA ADVANCED TECHNO CO., LTD., HORIBA, LTD., TOKYO METROPOLITAN GOVERNMENT
    Inventors: Akio Nakayama, Rumiko Furuya, Akio Ishii, Yasuto Kaba, Yuichi Ito, Susumu Yamauchi, Hiroaki Murakami, Atsushi Senda
  • Publication number: 20190025282
    Abstract: The purpose of the present invention is to provide a method for accurately predicting a cancer patient prognosis based on a count of desired cells for which expression of a leukocyte marker and an epithelial marker is hardly exhibited by detecting those cells. Provided is a method for diagnosing an overall survival prognosis for a patient suffering from cancer, the method including: a step of obtaining a concentrated solution containing desired cells by pre-treating a biological sample obtained from the patient; a step of optically detecting the concentrated cells; and a step of detecting the desired cells from the detected image, wherein an association is made with the overall survival prognosis diagnosis by counting the detected desired cells, and wherein the desired cells are cells confirmed by the existence of a cell nucleus and in which expression of a leukocyte marker and an epithelial marker is hardly exhibited.
    Type: Application
    Filed: January 19, 2017
    Publication date: January 24, 2019
    Applicants: TOSOH CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Yasuyuki AKIYAMA, Atsushi MORIMOTO, Toru FUTAMI, Fumiaki KOIZUMI, Takeshi SAWADA
  • Patent number: 9850649
    Abstract: A control plate is provided at a preferred position in a storm overflow chamber. An inflow pipe, an intercepting pipe, and an outflow pipe are connected to the storm overflow chamber. A vortex flow type water surface control device for a draining device includes the overflow chamber, and a control plate arranged in front of an opening portion of the intercepting pipe opening to the storm overflow chamber. A relation (1) 0.5 D?X?0.7 D and 0.83 D?Y?1.5 D holds true, or a relation (2) 0.4 D?X?0.5 D and 1.0 D?Y?1.5 D holds true, where D represents an inner diameter of the opening portion, X represents a projection length of the control plate with respect to the opening portion, and Y represents a distance between the control plate and the opening portion. As a result, contaminants enter the intercepting pipe.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: December 26, 2017
    Assignees: NIPPON KOEI CO., LTD, TOKYO METROPOLITAN SEWERAGE SERVICE CORPORATION, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Hiromi Watanabe, Hiroshi Komatsu, Shigeki Nishimura, Shigeru Tsukada
  • Patent number: 9134313
    Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: September 15, 2015
    Assignees: Tokyo Metropolitan Organization For Medical Research, CRC Inc., Tokyo Metropolitan Government, Trans Genic Inc.
    Inventors: Masao Kawakita, Kyoko Hiramatsu, Keiichi Takahashi, Naotaka Hamasaki, Koji Yamaguchi, Tsunehisa Kaku, Koichiro Muta, Munechika Enjoji, Seiji Naito, Jun Hayashi, Shoshu Mitsuyama, Hiroyuki Yamashita, Toru Inoue, Masato Kato
  • Patent number: 8979432
    Abstract: In a conventional storm overflow chamber of a combined sewer system, inflowing floating debris do not flow into an intercepting pipe in a rainy weather, and flow out to a public water body, causing a water pollution in the public water body. According to a vortex flow type water surface control device for a draining device of the present invention, a control plate (6) higher than at least a separating weir (1) is provided between an opening of an inflow pipe (2) and an opening of an intercepting pipe (3) in a storm overflow chamber of a combined sewer system. Moreover, a guide wall (7) higher than at least the separating weir (1) is provided along the separating weir between the opening of the inflow pipe (2) and the separating weir (1).
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: March 17, 2015
    Assignees: Tokyo Metropolitan Government, Tokyo metropolitan Sewerage Service Corporation, Nippon Koei Co., Ltd.
    Inventors: Ikuo Uemura, Hirofumi Ishiwada, Shouichi Banba, Aya Uchino, Tsuneo Ochiai, Hiroshi Komatsu, Shigeki Nishimura, Shigeru Tukada
  • Patent number: 8792977
    Abstract: The system of the present invention includes (a) means for displaying image information including a target image and a cursor image for tracking the target image; (b) means used when the subject moves the cursor image; (c) means for detecting the state of tracking the target image by the cursor image; (d) means for detecting the muscle active state of the subject using the means (b); (e) means for analyzing the tracking state detected by the means (c) and the muscle active state detected by the means (d); and (f) means for evaluating the motor function of the subject by using results of analysis obtained by the means (e) as indexes.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: July 29, 2014
    Assignees: Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Government
    Inventors: Shinji Kakei, Jongho Lee, Yasuhiro Kagamihara
  • Patent number: 8660641
    Abstract: The present invention provides a system for evaluating motor control function in the brain.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: February 25, 2014
    Assignees: Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Government
    Inventors: Shinji Kakei, Jongho Lee, Yasuhiro Kagamihara
  • Patent number: 8632104
    Abstract: A lock member capable of contacting an engaging projection of an inserted pipe section from a direction of the pipe axis and relatively rotatably attachable between an annular wall portion of a receiving pipe section and the engaging projection of the inserted pipe section includes engaging stopper portions projecting therefrom for contacting an inward surface of the annular wall portion from the direction of the pipe axis. The annular wall portion has attachment/detachment recesses formed therein for allowing inserting and removing movements of the engaging stopper portions in the direction of the pipe axis. An elastic urging member is provided between an extending portion projecting from the lock member to the outside of the pipe through an inner peripheral surface of the annular wall portion and the outer peripheral surface of the inserted pipe section, and an outward surface of the annular wall portion.
    Type: Grant
    Filed: November 24, 2005
    Date of Patent: January 21, 2014
    Assignees: Tokyo Metropolitan Government, Taisei Kiko Co., Ltd.
    Inventors: Go Horikawa, Fumiyoshi Miyazaki
  • Publication number: 20130240421
    Abstract: A control plate is provided at a preferred position in a storm overflow chamber. An inflow pipe, an intercepting pipe, and an outflow pipe are connected to the storm overflow chamber. A vortex flow type water surface control device for a draining device includes the overflow chamber, and a control plate arranged in front of an opening portion of the intercepting pipe opening to the storm overflow chamber. A relation (1) 0.5D?X?0.7D and 0.83D?Y?1.5D holds true, or a relation (2) 0.4D?X?0.5D and 1.0D?Y?1.5D holds true, where D represents an inner diameter of the opening portion, X represents a projection length of the control plate with respect to the opening portion, and Y represents a distance between the control plate and the opening portion. As a result, contaminants enter the intercepting pipe.
    Type: Application
    Filed: December 9, 2011
    Publication date: September 19, 2013
    Applicants: NIPPON KOEI CO., LTD., TOKYO METROPOLITAN GOVERNMENT, TOKYO METROPOLITAN SEWERAGE SERVICE CORPORATION
    Inventors: Hiromi Watanabe, Hiroshi Komatsu, Shigeki Nishimura, Shigeru Tsukada
  • Patent number: 8459900
    Abstract: A vortex flow type water surface control device for a draining device is provided. The vortex flow type water surface control device may include an inflow pipe, an outflow pipe, an intercepting pipe, and a separating weir that is disposed to block the intercepting pipe and the inflow pipe from the outflow pipe. The vortex flow type water surface control device may also include a control plate that is disposed between an opening of the inflow pipe and an opening of the intercepting pipe. A height of the control plate may be higher than at least a height of the separating weir. The control plate may be apart from the separating weir, and may approximately extend to a center axis of the intercepting pipe.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: June 11, 2013
    Assignees: Tokyo Metropolitan Government, Tokyo Metropolitan Sewerage Servce Corporation, Nippon Koei Co., Ltd.
    Inventors: Ikuo Uemura, Hirofumi Ishiwada, Shouichi Banba, Aya Uchino, Tsuneo Ochiai, Hiroshi Komatsu, Shigeki Nishimura, Shigeru Tukada
  • Publication number: 20110284441
    Abstract: A vortex flow type water surface control device for a draining device is provided. The vortex flow type water surface control device may include an inflow pipe, an outflow pipe, an intercepting pipe, and a separating weir that is disposed to block the intercepting pipe and the inflow pipe from the outflow pipe. The vortex flow type water surface control device may also include a control plate that is disposed between an opening of the inflow pipe and an opening of the intercepting pipe. A height of the control plate may be higher than at least a height of the separating weir. The control plate may be apart from the separating weir, and may approximately extend to a center axis of the intercepting pipe.
    Type: Application
    Filed: August 4, 2011
    Publication date: November 24, 2011
    Applicants: TOKYO METROPOLITAN GOVERNMENT, NIPPON KOEI CO. LTD., TOKYO METROPOLITAN SEWERAGE SERVICE CORPORATION
    Inventors: Ikuo UEMURA, Hirofumi ISHIWADA, Shouichi BANBA, Aya UCHINO, Tsuneo OCHIAI, Hiroshi KOMATSU, Shigeki NISHIMURA, Shigeru TUKADA
  • Publication number: 20110137196
    Abstract: The system of the present invention includes (a) means for displaying image information including a target image and a cursor image for tracking the target image; (b) means used when the subject moves the cursor image; (c) means for detecting the state of tracking the target image by the cursor image; (d) means for detecting the muscle active state of the subject using the means (b); (e) means for analyzing the tracking state detected by the means (c) and the muscle active state detected by the means (d); and (f) means for evaluating the motor function of the subject by using results of analysis obtained by the means (e) as indexes.
    Type: Application
    Filed: February 26, 2008
    Publication date: June 9, 2011
    Applicants: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, TOKYO METROPOLITAN GOVERNMENT
    Inventors: Shinji Kakei, Jongho Lee, Yasuhiro Kagamihara
  • Publication number: 20090298098
    Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 3, 2009
    Applicants: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, CRC Inc., Tokyo Metropolitan Government, Trans Genic Inc.
    Inventors: Masao KAWAKITA, Kyoko HIRAMATSU, Keiichi TAKAHASHI, Naotaka HAMASAKI, Koji YAMAGUCHI, Tsunehisa KAKU, Koichiro MUTA, Munechika ENJOJI, Seiji NAITO, Jun HAYASHI, Shoshu MITSUYAMA, Hiroyuki YAMASHITA, Toru INOUE, Masato KATO
  • Patent number: 7604263
    Abstract: A pipe joint construction comprising an elastic seal member (4) for hermetically sealing between an inner circumferential surface of a receiving pipe section (1) and an outer circumferential surface of an inserted pipe section (2) inserted into and connected to the receiving pipe section in a pipe axis direction (X), and a lock member (7) provided in the inner circumferential surface of the receiving pipe section (1) adjacent a receiving opening thereof for preventing separation of the pipe sections by contacting an engaging projection (5) protruding from the outer circumferential surface of the inserted pipe section (2) in the pipe axis direction, wherein the construction further comprises an attachment/detachment control device (A) for attaching and detaching the lock member (7) to/from the receiving pipe section (1) by rotating the lock member (7) about the pipe axis direction (X) relative to the receiving pipe section (1) and by moving, in the pipe axis direction (X), the lock member (7) placed in a speci
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: October 20, 2009
    Assignees: Tokyo Metropolitan Government, Taisei Kiko Co., Ltd.
    Inventors: Mitsuhiro Mori, Fumiyoshi Miyazaki
  • Publication number: 20080258463
    Abstract: A lock member 27 capable of contacting an engaging projection 22 of an inserted pipe section 8 from a direction of pipe axis X2 and relatively rotatably attachable between an annular wall portion 24 of a receiving pipe section 6 and the engaging projection of the inserted pipe section 8 includes engaging stopper portions 27a projecting therefrom for contacting an inward surface of the annular wall portion 24 from the direction of pipe axis X2. The annular wall portion 24 has attachment/detachment recesses 28 formed therein for allowing inserting and removing movements of the engaging stopper portions 27a in the direction of pipe axis X2.
    Type: Application
    Filed: November 24, 2005
    Publication date: October 23, 2008
    Applicants: TOKYO METROPOLITAN GOVERNMENT, TAISEI KIKO CO., LTD
    Inventors: Go Horikawa, Fumiyoshi Miyazaki
  • Publication number: 20080023074
    Abstract: In a conventional storm overflow chamber of a combined sewer system, inflowing floating debris do not flow into an intercepting pipe in a rainy weather, and flow out to a public water body, causing a water pollution in the public water body. According to a vortex flow type water surface control device for a draining device of the present invention, a control plate (6) higher than at least a separating weir (1) is provided between an opening of an inflow pipe (2) and an opening of an intercepting pipe (3) in a storm overflow chamber of a combined sewer system. Moreover, a guide wall (7) higher than at least the separating weir (1) is provided along the separating weir between the opening of the inflow pipe (2) and the separating weir (1).
    Type: Application
    Filed: August 2, 2004
    Publication date: January 31, 2008
    Applicants: TOKYO METROPOLITAN GOVERNMENT, TOKYO METROPOLITAN SEWERAGE SERVICE CORPORATION, NIPPON KOEI CO. LTD.
    Inventors: Ikuo Uemura, Hirofumi Ishiwada, Shouichi Banba, Aya Uchino, Tsuneo Ochiai, Hiroshi Komatsu, Shigeki Nishimura, Shigeru Tukada
  • Publication number: 20070158944
    Abstract: A pipe joint construction comprising an elastic seal member (4) for hermetically sealing between an inner circumferential surface of a receiving pipe section (1) and an outer circumferential surface of an inserted pipe section (2) inserted into and connected to the receiving pipe section in a pipe axis direction (X), and a lock member (7) provided in the inner circumferential surface of the receiving pipe section (1) adjacent a receiving opening thereof for preventing separation of the pipe sections by contacting an engaging projection (5) protruding from the outer circumferential surface of the inserted pipe section (2) in the pipe axis direction, wherein the construction further comprises an attachment/detachment control device (A) for attaching and detaching the lock member (7) to/from the receiving pipe section (1) by rotating the lock member (7) about the pipe axis direction (X) relative to the receiving pipe section (1) and by moving, in the pipe axis direction (X), the lock member (7) placed in a speci
    Type: Application
    Filed: December 15, 2004
    Publication date: July 12, 2007
    Applicants: TOKYO METROPOLITAN GOVERNMENT, TAISEI KIKO CO., LTD.
    Inventors: Mitsuhiro Mori, Fumiyoshi Miyazaki
  • Patent number: 5203901
    Abstract: A processing method is presented for treating sludges from municipal and waste materials. The ashes from such sludges, containing SiO.sub.2 as a primary constituent, are treated with additives to tailor the feed material composition. Thermal processing, including melting, rapid cooling and subsequent annealing, produces a crystallized glass microstructure in which needle-shaped shaped crystals of anorthite and .beta.-wollastnite are infiltrated with a vitreous material. Such crystallized glasses having superior mechanical and aesthetic properties are an attractive architectural material which can be utilized for interior finishing, exterior walls, flooring as well as for interior decorations.
    Type: Grant
    Filed: December 18, 1991
    Date of Patent: April 20, 1993
    Assignees: Tsukishima Kikai Co., Ltd., Tokyo Metropolitan Government
    Inventors: Shigeru Suzuki, Keiichiro Miyano, Takumi Kaneko, Yoshikazu Nagayoshi