Abstract: Synthetic peptides containing the following specific sequence:Xaa-Pro-Val-Xbb-Xcc-Lys-Arg-W (wherein Xaa is absent or represents Cys or Ser, Xbb represents His or Asn, Xcc represents Leu or Ile and W represents a hydrophobic peptide portion.), an intermediate for producing the peptide, a process for producing the peptide, a lung surfactant comprising the peptide and a lipid mixture and a remedy for respiratory distress syndrome containing the surfactant as the active ingredient. The peptide is easy to isolate and purify and suitable for mass production. As it is highly soluble in methanol and the like, it can readily be blended with a lipid mixture and is suited for the preparation of a lung surfactant. As the lung surfactant has a good supensibility and a potent surface activity, it is useful as a remedy for respiratory distress syndrome.

Abstract: An aqueous preparation for the treatment of allergic diseases comprising 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt, dibasic potassium phosphate and monobasic potassium phosphate. The aqueous preparation has no local irritation yet has physicochemical stability during long-term storage.

Abstract: Imidazo[4,5-b]pyridine compounds of the general formula [I] are provided: ##STR1## where R.sup.1 is straight-chain or branched C.sub.1-8 alkoxy which may be substituted with cycloalkyl, or C.sub.2-4 fluoroalkyloxy, R.sup.2 is H, methyl or methoxy, and R.sup.3 and R.sup.4 are each H or methyl and may be the same or different. All these compounds have good activity of inhibiting potassium ion-dependent adenosine triphosphatase and excellent storage stability, so that they are usable for the treatment of gastric and/or duodenal ulcers.

Abstract: Benzimidazole derivatives of the general formula [I] are provided: ##STR1## wherein R.sup.1 is hydrogen, methyl or methoxy, and R.sup.2 and R.sup.3 each is hydrogen or methyl, at least one of R.sup.1, R.sup.2 and R.sup.3 being a member other than hydrogen. The benzimidazole derivatives exhibit an excellent activity of inhibiting the potassium ion-dependent adenosine triphosphatase, as well as a good stability during storage. Therefore, the benzimidazole derivatives are usable for the treatment of gastric and/or duodenal ulcers.

Abstract: N-(3,3-Diphenylpropyl)-N'-aralkyl-substituted piperazines which have a structure in which a hydrogen in the N'-benzene ring has been substituted for by --(OCH.sub.3).sub.n (in which n represents an integer from 0 - 3) were synthesized. These compounds are novel compounds that are not found in literature, and have a coronary blood flow increasing action in considerably lower amounts than do conventional piperazine compounds having similar effects.