Abstract: The present invention provides a method for purification of a recombinant protein, in particular to a recombinant human albumin; the method includes: (a) adding aminoguanidine and a medium-long chain fatty acid to a sample containing the recombinant protein; and (b) chromatographing the obtained sample, where the chromatography is optionally performed with a chromatographic buffer solution containing aminoguanidine.
Abstract: A preparation method of a human albumin-containing medical product comprises controlling a content of long-chain fatty acids in the medical product and adding poloxamer to the medical product. The long-chain fatty acid is one or more selected from myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid and arachidonic acid, and a molar ratio of the long-chain fatty acids and human albumin is 0.2-3.0. A content of the poloxamer is 10-500 ?g/g of human albumin. The human albumin-containing medical product prepared by the method has improved stability and does not contain particle of over 30 nm in diameter is formed from aggregation and/or fibrillation of human albumin.